Regenerative Engineering of Musculoskeletal Tissues- a Convergence Doctoral Training Program

肌肉骨骼组织再生工程-融合博士培训项目

基本信息

批准号：
10792362
负责人：
CATO T. LAURENCIN
金额：
$ 14.74万
依托单位：
UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-07-01 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10792362
关键词：
Musculoskeletal Regenerative engineering Tissues Training Programs

项目摘要

PROJECT SUMMARY / ABSTRACT We propose a novel NIAMS doctoral T32 Program, Regenerative Engineering of Musculoskeletal Tissues: A Convergence Doctoral Training Program, which offers inter-disciplinary research areas at the University of Connecticut (UConn) combining biomedical science and engineering faculties. Regenerative Engineering is defined as the Convergence of advanced materials science, stem cell science, physics, developmental biology and clinical translation for the regeneration of complex tissues and organ systems. The T32 Program will enroll 2 Ph.D. candidates per year and support each for 2 years of Graduate School. The students will be drawn from graduate programs at UConn (School of Medicine and School of Engineering). The students will then apply for T32 support at the end of Year 1 of graduate school to be supported for Years 2-3. They will all receive their Ph.D. from the Graduate School at UConn. The T32 Program will offer trainees a broad level of expertise in research and instruction based on the research, educational, and clinical experiences of the biomedical and engineering faculty who serve as preceptors. Trainees will become experts in regenerative engineering and its foundations to work towards the alleviation of human disease and musculoskeletal injuries by means of tissue regeneration. Musculoskeletal regeneration is a field ripe for an inventive approach based on convergence to address challenging issues, advance technology and further fundamental knowledge for therapeutic applications. At the center of the Convergence approach is the understanding that new solutions in regeneration will take place through an `un-siloed' approach. Thus, Regenerative Engineering welcomes ideas and research across a gamut of disciplines. The T32 Program has preceptorship commitments from 20 distinguished faculty at UConn (representing Biomedical Engineering, Cell Biology, Computer Science, Genetics and Genome Sciences, Materials Science, Mechanical Engineering, Molecular Biology and Biophysics, Oral Health, Orthopedic Surgery). This eminent group of investigators is well funded and published to provide the primary research training and serve as role models for doctoral trainees Our Program strengths include its interdisciplinary and collaborative research in biomedical science and engineering, interactions with diverse trainees and faculty, training in contemporary research methodologies, and successful preceptors. T32 Program administration through the Connecticut Convergence Institute for Translation in Regenerative Engineering will provide the experience to recruit diverse trainees, including minorities, implement the curriculum, and train a new cadre of convergence scientists.

项目概要/摘要我们提出了一个新的 NIAMS 博士 T32 项目，肌肉骨骼组织的再生工程：融合博士培训计划，在大学提供跨学科研究领域康涅狄格大学 (UConn) 结合了生物医学科学和工程学院。再生工程被定义为先进材料科学、干细胞科学、物理学、发育科学的融合复杂组织和器官系统再生的生物学和临床转化。 T32计划将招收博士2名每年的候选人，并支持每人 2 年的研究生院。学生们将来自康涅狄格大学（医学院和工程学院）的研究生课程。学生们然后将在研究生院第 1 年结束时申请 T32 支持，以便在第 2-3 年获得支持。他们都将获得博士学位。来自康涅狄格大学研究生院。 T32 计划将为学员提供广泛的基于研究、教育和临床经验的研究和指导专业水平担任导师的生物医学和工程教师。学员将成为以下领域的专家再生工程及其致力于减轻人类疾病和疾病的基础通过组织再生造成的肌肉骨骼损伤。肌肉骨骼再生是一个成熟的领域基于融合的创造性方法来解决具有挑战性的问题，推进技术并进一步治疗应用的基础知识。融合方法的核心是了解再生的新解决方案将通过“非孤立”方法实现。因此，再生工程欢迎跨学科的想法和研究。 T32计划康涅狄格大学 20 名杰出教师（代表生物医学工程学、细胞生物学、计算机科学、遗传学和基因组科学、材料科学、机械工程、分子生物学和生物物理学、口腔健康、骨科手术）。这位杰出的研究人员小组资金充足并发表论文，可提供主要研究培训并充当博士生的榜样我们的项目优势包括跨学科和协作生物医学科学与工程研究、与不同学员和教师的互动、培训当代的研究方法和成功的导师。 T32 计划管理通过康涅狄格州再生工程翻译融合研究所将提供经验招募包括少数族裔在内的多元化学员、实施课程并培养新的骨干人员趋同科学家。

项目成果

期刊论文数量（19）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Biodegradable Polyphosphazenes for Regenerative Engineering.

用于再生工程的可生物降解的聚磷腈。

DOI：
发表时间：
2022-04
期刊：
影响因子：
2.7
作者：
Chen, Feiyang;Teniola, O R;Laurencin, Cato T
通讯作者：
Laurencin, Cato T

The effect of metformin on influenza vaccine responses in nondiabetic older adults: a pilot trial.

二甲双胍对非糖尿病老年人流感疫苗反应的影响：一项试点试验。

DOI：
发表时间：
2023-05-02
期刊：
影响因子：
0
作者：
Martin, Dominique E;Cadar, Andreia N;Panier, Hunter;Torrance, Blake L;Kuchel, George A;Bartley, Jenna M
通讯作者：
Bartley, Jenna M

Old drug, new tricks: the utility of metformin in infection and vaccination responses to influenza and SARS-CoV-2 in older adults.

老药，新花样：二甲双胍在老年人流感和 SARS-CoV-2 感染和疫苗接种反应中的效用。