Clinical Research and Assay Support

临床研究和检测支持

• 批准号: 7734330
• 负责人: Mary Walter
• 金额: $ 42.55万
• 依托单位: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7734330
• 关键词: Aliquot; Biological Assay; Clinical Investigator; Clinical Research; Contracts; Core Facility; Databases; Diabetes Mellitus; Goals; Human; Institutes; Instruction; Intramural Research Program; Kidney Diseases; Label; Leptin; Measures; Methods; Nonesterified Fatty Acids; Numbers; Plasma; Principal Investigator; Process; Protocols documentation; Research Personnel; Running; Sampling; Services; Shipping; Ships; Site; Specimen; System; Testing; Week; des-n-octanoyl ghrelin; ghrelin; glucagon-like peptide 1

The Clinical Research Core is responsible for processing human samples from numerous clinical studies currently in progress. Once the samples are acquired we process it according to the instructions on the protocol, aliquot, label and store the samples for the various principal investigators as per their instructions. We are currently processing an average of 986 samples/week. All samples processed in the lab are set up with a tracking number and entered into a database which is maintained by the Core lab. Studies that have started since January 2008 are labeled using a 2D-barcode system developed in our lab. The Core lab has also set up a biorepository service with Fisher Bioservices for long term off-site storage of samples. In addition to the biorepository needs of the PIs, the Clinical Research Core also provides assay services for analyses which are currently not available at DLM. We have tested and validated numerous methods to measure Glucagon-like Peptide-1, Acyl Ghrelin, Desacyl Ghrelin, Leptin and Free fatty acid in human plasma.

临床研究核心负责处理目前正在进行的许多临床研究的人类样本。 获取样品后，我们根据协议的说明，等分试样，标记和存储各种主要研究人员的样品，按照其说明进行处理。 我们目前平均每周处理986个样本。 实验室中处理的所有样本均使用跟踪号进行设置，并输入由Core Lab维护的数据库。自2008年1月以来开始的研究使用我们实验室中开发的2D-Barcode系统标记。 核心实验室还使用Fisher Bioservices建立了生物座位服务，用于长期现场存储样品。 除了PIS的生物验证需求外，临床研究核心还为DLM目前尚不可用的分析提供了测定服务。 我们已经测试并验证了许多方法，用于测量人血浆中胰高血糖素样肽-1，酰基生长素蛋白，乙酰糖蛋白，瘦素和游离脂肪酸。