Epidemiology - National Comorbidity Survey Replication

流行病学 - 全国合并症调查复制

• 批准号: 7871127
• 负责人: RONALD C KESSLER
• 金额: $ 51.01万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7871127
• 关键词: Accounting; Address; African American; Agreement; Algorithms; Archives; Asian Americans; Clinical; Cohort Effect; Collaborations; Communities; Comorbidity; Complex; Computers; Consult; DSM-IV; DSM-V; Data; Data Files; Data Set; Diagnosis; Diagnostic; Diagnostic and Statistical Manual; Disease; Economics; Educational workshop; Electronics; Epidemiology; Family; Funding; Grant; Health Alliance; Health Care Sector; Household; Impairment; Individual; Institutes; Internet; Interview; Interviewer; Joints; Latino; Letters; Life Cycle Stages; Medical; Mental Health; Mental disorders; Methodological Studies; Michigan; National Institute of Mental Health; Prevalence; Procedures; Psyche structure; Psychology; Reporting; Research; Research Personnel; Retrospective Studies; Role; Science; Services; Severities; Sociology; Survey Methodology; Surveys; System; Time; Time Study; Training; Universities; Update; Visit; Work; base; clinically significant; comparative; design; laptop; programs; prospective; social; trend

DESCRIPTION (provided by applicant): This application seeks support for continued analysis of the National Comorbidity Survey Replication (NCS-R), a nationally representative household survey of the prevalence and correlates of DSM-IV. The two original NCS-R specific aims were: to investigate time trends in the prevalence and correlates of mental disorders over the decade of the 1990s by comparing results in the results of the baseline NCS; and to expand the assessment of prevalence and correlates beyond the NCS. To these ends, the NCS-R repeated many NCS questions, updated diagnostic assessments to DSM-IV criteria (vs. DSM-III-R in the baseline NCS), expanded the number of disorders assessed, and included many new questions not in the NCS. The current application has four specific aims: (1) to disseminate and support a public use NCS-R dataset; (2) to complete analyses for the NCS-R aim of studying time trends in prevalence, treatment, treatment adequacy, and correlates compared to the baseline NCS; (3) to complete analyses for the NCS-R aim of addressing important substantive and methodological issues that were not covered in the baseline NCS; and (4) to continue our collaboration with NIMH and other colleagues in the larger U01 who are carrying out separate African-American and Latino/Asian-American surveys. The third aim is the most complex of the four, as it has six sub-aims. These include the following: (i) to estimate the prevalence, clinical severity, and correlates of individual DSM-IV disorders, expanding the number and variety of disorders assessed compared to the NCS; (ii) to evaluate disorder-specific nosological issues aimed at guiding revisions of the DSM-V system; (iii) to estimate the comparative effects of individual mental and physical disorders on role functioning and utilities; (iv) to analyze the ways in which comorbidity adds to the impairments associated with individual mental disorders; (v) to analyze the effects of mental vs. physical disorders on family burden; and (vi) to analyze the temporal unfolding of multivariate comorbid disorder profiles over the life course.

描述（由申请人提供）：本申请寻求支持对国家合并症调查复制（NCS-R）的持续分析，这是全国代表性的家庭调查DSM-IV的患病率和相关性。两个原始的NCS-R具体目的是：研究1990年代十年来，通过比较基线NC的结果，研究精神障碍的患病率和相关性的时间趋势；并扩大对患病率的评估并将其关联到NC之外。对于这些目的，NCS-R重复了许多NCS问题，更新了DSM-IV标准的诊断评估（与基线NCS中的DSM-III-R相比），扩大了评估的疾病数量，并包括许多NC中的许多新问题。当前的应用程序具有四个特定的目的：（1）传播和支持公共使用NCS-R数据集； （2）与基线NC相比，针对NCS-R的目的分析了患病率，治疗，适当性和相关性的时间趋势； （3）完成NCS-R目的的分析，以解决基线NC中未涵盖的重要实质性和方法论问题； （4）继续我们与NIMH和其他同事的合作，他们正在进行单独的非裔美国人和拉丁美洲/亚裔美国人的调查。第三个目标是这四个目标中最复杂的，因为它具有六个sub-aim。其中包括以下内容：（i）估计单个DSM-IV疾病的患病率，临床严重程度和相关性，从而扩大了与NCS相比评估的疾病的数量和种类； （ii）评估旨在指导DSM-V系统修订的障碍特异性问题； （iii）估计个人心理和身体障碍对角色功能和公用事业的比较影响； （iv）分析合并症增加与个人精神障碍相关的障碍的方式； （v）分析心理与身体障碍对家庭负担的影响； （vi）分析在生活过程中多元合并症概况的时间展开。