Biology Core

生物核心

• 批准号: 7756642
• 负责人: Eric A. Whitsel
• 金额: $ 77.72万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7756642
• 关键词: Adolescent; Archives; Biological; Biological Assay; Biological Markers; Biology; Collaborations; Collection; Consultations; Data; Data Collection; Data Quality; Documentation; Ensure; Equipment and supply inventories; Goals; Grant; Health; Hydrocortisone; Incentives; Interviewer; Laboratories; Leadership; Longitudinal Studies; Measurement; Measures; Monitor; Paper; Pharmaceutical Preparations; Preparation; Process; Protocols documentation; Research; Research Design; Research Methodology; Research Personnel; Sampling; Science; Specimen; System; Theoretical model; Training; Work; base; innovation; member; programs; research and development; research study; sample collection

In Year 13, the Biology Core will work closely with the Data Collection subproject and Dissemination Core to monitor all aspects of main study biological data collection and the resulting specimen archive. The Biology Core will have primary responsibility for monitoring the quality and reliability of biological specimens and data, including anthropometric measurements, medication inventory data, and assay results. The Core will also oversee systems for the tracking, storage and archiving of biological samples. By reviewing data distributions and value ranges, the Biology Core will assist the Dissemination Core in data cleaning and dissemination. The Biology Core will also provide documentation of data collection protocols, specimen collection and biological measures to the Dissemination Core for distribution to data users. To ensure that the science produced with the biological data from Add Health is consistent with the scientific goals of our project, the Biology Core will continue to evaluate proposals by researchers seeking to use archived biological specimens. Reviews will be submitted to the Project Director, who, in collaboration with the Deputy Director and Biology Core Pis, will decide whether to grant and/or recommend changes in the researcher's request. Throughout Year 13, the Biology core will continue to provide scientific guidance and advice for the integration of biological paradigms and data into subproject theoretical models and analysis plans. Scientific guidance and advice will occur through mutual work and collaboration among Biology Core members and Program Investigators. The Biology Core will also assist in the preparation of research methods papers based on the results of the cortisol and incentive experiments embedded in the Wave IV pretest.

在第13年中，生物学核心将与数据收集的副本和传播核心紧密合作 监视主要研究生物数据收集和由此产生的标本档案的所有方面。生物学 核心将负责监视生物标本和数据的质量和可靠性， 包括人体测量值，药物清单数据和测定结果。核心也将 监督用于跟踪，存储和归档生物样品的系统。 通过审查数据分布和价值范围，生物学核心将有助于数据中的传播核心 清洁和传播。生物核心还将提供数据收集协议的文档， 标本收集和生物学措施向传播核心分配给数据用户。 为了确保使用ADD健康生物数据产生的科学与科学一致 我们项目的目标，生物学核心将继续评估寻求使用的研究人员的建议 存档的生物标本。评论将提交给项目主任，后者与 副主任和生物学核心PIS将决定是否授予和/或建议更改 研究人员的要求。 在整个13年中，生物学核心将继续为整合提供科学指导和建议 生物学范例和数据中的研究理论模型和分析计划。科学指导 和建议将通过生物学核心成员和计划之间的共同工作和协作进行 调查人员。生物学核心还将协助根据基于 皮质醇和激励实验的结果嵌入了波IV预测中。