Novel Static Screen Volumetric 3D Display for Medical Image Visualization

用于医学图像可视化的新型静态屏幕体积 3D 显示

• 批准号: 7663381
• 负责人: Jason Geng
• 金额: $ 15.76万
• 依托单位: XIGEN, LLC
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7663381
• 关键词: Address; Adoption; Affect; Anatomic structures; Anatomy; Arts; Breast; Caliber; Clinical; Collaborations; Color; Complex; Computational Science; Computer software; Cues; Development; Devices; Dimensions; Engravings; Eye; Eyeglasses; Feasibility Studies; Future; Glass; Head; Height; Human; Image; Imagery; Imaging technology; Institutes; Knowledge; Lasers; Life; Light; Magnetic Resonance Imaging; Maintenance; Medical; Medical Education; Medical Imaging; Medical Research; Monitor; Nature; Operative Surgical Procedures; Patients; Phase; Physiological; Positioning Attribute; Principal Investigator; Procedures; Production; Prostate; Radiation; Radiation Oncology; Radiation therapy; Research; Resolution; Resources; Retinal blind spot; Safety; Shapes; Small Business Innovation Research Grant; Solutions; Speed; Structure; Surface; System; Technology; Television; Testing; Three-Dimensional Image; Time; Training; Treatment Effectiveness; United States National Institutes of Health; Visual system structure; Work; base; clinical Diagnosis; cost; design; experience; flexibility; image processing; image visualization; imaging modality; innovation; millimeter; novel; oncology; programs; prototype; psychologic; public health relevance; response; success; treatment planning; two-dimensional; ultra high resolution

DESCRIPTION (provided by applicant): Novel Static Screen Volumetric 3D Display for Medical Image Visualization Phase I proposal in response to NIH SBIR PAR-07-160 "Innovations in Biomedical Computational Science and Technology Initiative", Submitted by Xigen LLC on 08/05/2008, in collaboration with Department of Radiation Oncology, Johns Hopkins Medical Institute Project Summary Recent advances in medical imaging technology have led to the availability of high resolution 3D and 4D images of patients. These images are inherently of 3D nature, yet all conventional displays use flat 2D screens that lack important depth cues. While rendering software using 2D display monitors are quite effective in presenting 3D aspects of the imaging modalities, they are often inadequate. This fundamental restriction greatly limits the capability of clinicians to perceive the complexity of the 3D anatomy and treatment plan, therefore affects the safety, speed, accuracy, and effectiveness of the treatment procedures. In contrast to conventional 2D display, the "volumetric 3D display" we proposed herein possesses a true 3D display volume, and places physically each 3D "voxel" in the displayed 3D images at the true 3D (x, y, z) spatial position. Each voxel, analogous to a pixel in a 2D image, emits light from that position to form a real 3D image in the eyes of viewers. The volumetric 3D display technology provides both physiological and psychological depth cues to human visual system to perceive 3D objects and is considered as the Holy Grail solution to true 3D visualization of medical image, as well as many other image display problems. For the past ten years, the principal investigator of this SBIR has been working on developing the state-of- the-art volumetric 3D display technologies. Although our previous development achieved a high success, one of the major limitation of this type of volumetric display systems is that its 3D display volume is generated by a large size moving screen that rotates constantly at the speed of 600~1800 RPM. The structure of a moving screen dramatically complicates the design, production, use, and maintenance of the display system, making it very delicate and fragile for daily uses and expensive for widespread adoption for medical image visualizations. Xigen LLC has recently made a technology breakthrough and developed a revolutionary new concept of volumetric 3D display, which totally eliminates any moving screen. The unique advantages of the proposed static screen volumetric 3D display technology include: z No moving screen; z Inherent parallel mechanism for 3D voxel addressing; z High spatial resolution; z Full color display is easy to implement z Fine voxel size (at a sub-millimeter level); z No blind spot on the display volume and the display volume can be of arbitrary shape. z Simple and elegant system structure design; z No special viewing glasses or any special eyewear is needed to view the 3D images; z No image jitter affect that is associated with moving screen; z Low-cost and low-maintenance. We have already performed considerable preliminary feasibility studies to verify the validity of the proposed concept and implementation strategy. We propose this SBIR program to build a high resolution version of prototype hardware and develop associated software platform. PUBLIC HEALTH RELEVANCE: The primary objective of this Phase I SBIR effort is to demonstrate the feasibility of a novel volumetric 3D display concept with the unprecedented static screen high resolution volumetric 3D display capability. We have already performed considerable preliminary feasibility studies to verify the validity of the proposed concept and implementation strategy. We propose this SBIR program to build a high resolution version of prototype hardware and develop associated software platform to demonstrate its application for medical image visualization. The major innovations of this SBIR effort include: z Introduction of the Laser Sub-surface Engraving technology into the dynamic volumetric 3D display; z The "voxel column" concept that converts the crystal block and a 2D image projection into an addressable dynamic volumetric 3D display device, with a static screen; z The "Time Division" and "Diffraction Wheel" concepts that facilitate the ultra-high-resolution image projection from single DMD projection system for the high-resolution volumetric 3D display. Specific aims of our Phase 1 program include: Aim 1: Working with clinical experts to define the 3D Crystal requirements; Aim 2: Design and build a high resolution prototype of the 3D-Crystal screen; Aim 3: Design and build a high resolution image projection engine; Aim 4: Develop image processing and control software for the 3D-Crystal volumetric 3D display system; Aim 5: Perform extensive tests on the volumetric 3D display prototype; Aim 6: Collaborate with imaging experts at Johns Hopkins to demonstrate advantages of volumetric 3D display for medical image visualization; Aim 7: Develop optimal design of "clinically-testable" version of 3D-Crystal display based on the Phase 1 prototype experience, and prepare for Phase 2 work plan. The Phase 2 follow-on program should afford us with sufficient resources to design, build and test a clinically-testable version of functional high resolution volumetric 3D display. The proposed true 3D display technology adds one more dimension (literally and figuratively) to many medical image visualization applications. It is not meant to replace traditional 2D display and 3D rendering visualization systems, but rather to augment them, giving the viewers the unique power and flexibility to unambiguously visualize 3D complex information. If succeed, this ground breaking effort will have a significant impact on medical research and will revolutionize many current practices in medical image visualization, clinical diagnosis, radiation therapy planning, reconstructive and corrective surgery, medical education, training, and medical research. . Key Words Medical imaging, image visualization, image processing, three dimensional display, volumetric, static screen.

DESCRIPTION (provided by applicant): Novel Static Sc​​reen Volumetric 3D Display for Medical Image Visualization Phase I proposal in response to NIH SBIR PAR-07-160 "Innovations in Biomedical Computational Science and Technology Initiative", Submitted by Xigen LLC on 08/05/2008, in collaboration with Department of Radiation Oncology, Johns Hopkins Medical Institute Project Summary Recent advances in medical imaging technology have led to the高分辨率3D和4D患者图像的可用性。这些图像本质上是3D性质，但是所有常规显示器都使用缺乏重要深度提示的平面2D屏幕。虽然使用2D显示监视器渲染软件在呈现成像方式的3D方面非常有效，但它们通常不足。因此，这种基本限制极大地限制了临床医生感知3D解剖和治疗计划的复杂性的能力，因此会影响治疗程序的安全性，速度，准确性和有效性。与传统的2D显示相反，我们在本文提出的“体积3D显示”具有真实的3D显示体积，并且在显示的3D（X，Y，Z）空间位置的显示的3D图像中，将每个3D“ Voxel”物理放置在显示的3D图像中。每个体素（类似于2D图像中的像素）从该位置发出光，以在观众眼中形成真实的3D图像。体积3D展示技术为人类视觉系统提供了生理和心理深度线索，以感知3D对象，并被视为医学图像真实3D可视化的圣杯解决方案，以及许多其他图像显示问题。在过去的十年中，该SBIR的主要研究人员一直致力于开发最新的体积3D展示技术。尽管我们以前的开发取得了很高的成功，但这种体积显示系统的主要局限性之一是其3D显示体积是由大型移动屏幕生成的，该屏幕以600至1800 rpm的速度不断旋转。移动屏幕的结构极大地使展示系统的设计，生产，使用和维护变得复杂，使其对于日常用途非常微妙而脆弱，并且对于医疗图像可视化的广泛采用而言，它非常昂贵。 Xigen LLC最近取得了技术突破，并开发了革命性的体积3D显示器概念，这完全消除了任何移动屏幕。提议的静态屏幕体积3D显示技术的独特优势包括：z无移动屏幕； z 3D素的固有平行机制； z高空间分辨率； z全彩色显示易于实现Z细素大小（在亚毫米级别上）； z显示量没有盲点，显示量可以是任意形状的。 z简单而优雅的系统结构设计； Z不需要特殊的观看眼镜或任何特殊的眼镜来查看3D图像； z没有与移动屏幕相关的图像抖动影响； Z低成本和低维护。我们已经进行了大量的初步可行性研究，以验证拟议的概念和实施策略的有效性。我们建议使用此SBIR程序来构建原型硬件的高分辨率版本并开发关联的软件平台。公共卫生相关性：这阶段I SBIR工作的主要目标是证明具有前所未有的静态屏幕高分辨率体积3D显示能力的新型体积3D显示概念的可行性。我们已经进行了大量的初步可行性研究，以验证拟议的概念和实施策略的有效性。我们建议使用此SBIR程序来构建原型硬件的高分辨率版本，并开发关联的软件平台，以展示其用于医疗图像可视化的应用。这项SBIR工作的主要创新包括：Z引入激光地下雕刻技术到动态体积3D显示屏中； z“ Voxel列”概念将Crystal块和2D图像投影转换为带有静态屏幕的可寻址动态体积3D显示器； z“时间划分”和“衍射轮”概念，可促进高分辨率体积3D显示器的单个DMD投影系统的超高分辨率图像投影。我们1阶段计划的具体目标包括：目标1：与临床专家合作定义3D晶体要求； AIM 2：设计并构建3D晶体屏幕的高分辨率原型； AIM 3：设计和建造高分辨率图像投影引擎； AIM 4：为3D晶体体积3D显示系统开发图像处理和控制软件； AIM 5：对体积3D显示原型进行广泛的测试；目标6：与约翰·霍普金斯（Johns Hopkins）的成像专家合作，以展示体积3D显示的优势，以进行医学图像可视化； AIM 7：根据第1阶段原型体验开发3D-晶体显示的“临床检验”版本的最佳设计，并为第二阶段的工作计划做准备。第2阶段后续计划应为我们提供足够的资源来设计，构建和测试功能性高分辨率体积3D显示屏的临床测试版本。提出的真实3D显示技术为许多医学图像可视化应用程序增加了一个（从字面上和形象上）增加一个维度。它并不是要替换传统的2D显示屏和3D渲染可视化系统，而是要增强它们，从而为观众提供独特的力量和灵活性，以明确可视化3D复杂信息。如果成功，这项破裂的工作将对医学研究产生重大影响，并将彻底改变医学图像可视化，临床诊断，放射治疗计划，重建性和纠正手术，医学教育，培训和医学研究的许多当前实践。 。关键单词医学成像，图像可视化，图像处理，三维显示，体积，静态屏幕。