Scripps Translational Science Institute (UL1)

斯克里普斯转化科学研究所 (UL1)

• 批准号: 7920737
• 负责人: Eric Jeffrey Topol
• 金额: $ 59.71万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-24 至 2012-09-23
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7920737
• 关键词: Scripps; Translational; Science; Institute; UL1

With the excitement of the scientific landscape, in such areas as genomics, regenerative medicine, aging and the mind, there has never been a more favorable time to harness the opportunity to re-engineer a center, accelerate discoveries and foster education which will improve health. Scripps has responded to this backdrop and charge with a creative infrastructure that is intended to achieve transformation employing innovative strategies to hybridize the basic and clinical programs and unprecedented institutional commitments. The Scripps Translational Science Institute (STSI) will emphasize three dimensions of translation: (1) traditional , bench to bedside, (2) bedside to bench and back to bedside, and (3) bedside to the community and practice of medicine. STSI exploits the excitement of today's scientific advances to catapult tomorrow's preventions,. betterment of health, and the training of the future leaders of academic medicine. The vision of our program provides the appropriate amalgam of "integration and innovation," and the remarkable opportunity to capitalize on particular strengths at The Scripps Research Institute (TSRI), the largest biomedical research institute in the United States, and partnering institutions and faculty that have led to the development of 4 over-arching goals of the STSI (the 4 Ts").(1) Ignite the spirit of discovery of highlyrcharged interdisciplinary research, coupling translational, clinical and community-based investigation'(2) Inspire trainees . and young faculty through innovative curriculum and learning experiences, promoting not only scientific productivity but dedicated translational research and education career paths; (3) Integrate the efforts at TSRI and Scripps Health and partnering institutions in the community by building on existing programs, in the pursuit I of unprecedented engagement of the population of San Diego; and (4) Infrastructure and informatics buildup to ': potentiate and accelerate the ambitious needs of the program. Parallel to the outstanding NCRR and overall | NIH support to Scripps, the Scripps Health system has provided a massive, unprecedented investment that fully | certifies its priority and willingness to take on risk to promote heightened academic transformation. Building j upon and establishing genuine, specific collaborations with leading translational science investigators in a 0.5 mile hub on N, Torrey Pines Rd has greatly enriched the academic capabilities for STSI's success. Furthermore, collaborations with a large subset of the 550 life science companies in San Diego provide an , extraordinary advantage for accessing innovative technology and catalyzing patient benefit-San Diego's rich life science has truly been galvanized by STSI. By virtue of the re-engineered infrastructure and enhanced plasticity, STSI is perfectly poised to access the very large and diverse San Diego population through its dominant health care system and well established community education and research programs that have consistently focused on under-represented minorities. STSI will have a substantive impact on improving medicine and training physician-investigator leaders for the future..

随着科学景观的兴奋，在基因组学，再生医学，衰老和 思想，从来没有比较有利的时间来利用机会重新设计一个中心， 加速发现和促进教育，这将改善健康。斯克里普斯已经回应了这个背景 并通过旨在采用创新的创新基础设施来收费 融合基本和临床计划以及前所未有的机构承诺的策略。这 Scripps翻译科学研究所（STSI）将强调翻译的三个维度：（1）传统 ，长凳到床边，（2）床边到长凳，然后回到床边，（3）社区的床边和练习 药品。 STSI利用了当今科学进步明天的预防的兴奋。 改善健康，以及对学术医学未来领导者的培训。 我们计划的愿景提供了适当的“整合与创新”的融合，以及 在Scripps研究所（TSRI）上利用特定优势的巨大机会，最大的 美国的生物医学研究所，以及导致的机构和教职员工 开发STSI的4个超大目标（4 ts”）。（1）点燃发现高度收获的精神 跨学科研究，耦合翻译，临床和社区调查”（2）激发学员 。以及通过创新课程和学习经验的年轻教师，不仅促进科学 生产力，但专门的翻译研究和教育职业道路； （3）整合TSRI的努力 并通过构建现有计划，追求现有计划来确定社区中的健康和合作机构 圣地亚哥人口前所未有的i; （4）基础架构和信息学构建 '：增强和加速该计划的雄心勃勃的需求。与杰出的NCRR平行 | NIH对Scripps的支持，Scripps Health System提供了一项巨大的，前所未有的投资 |证明其优先考虑和愿意承担风险以促进发展的学术转变。建筑 j在0.5中与领先的转化科学研究者建立真正的，具体的合作 托里·派恩斯路（Torrey Pines Rd）在N上的Mile Hub极大地丰富了STSI成功的学术能力。 此外，与圣地亚哥的550家生命科学公司的大部分集合合作提供了 ，访问创新技术和催化患者福利 - 萨南迭戈的富人的巨大优势 生命科学确实被STSI镀锌。 凭借重新设计的基础设施和增强的可塑性，STSI完美地准备访问 通过其主导的医疗保健系统和良好的社区，大型和多样化的圣地亚哥人口 一直集中在代表性不足的少数群体上的教育和研究计划。 STSI会有 对未来改善医学和培训医师评估者领导者的实质性影响。