ERC Einstein Rockefeller CUNY Center for AIDS Research

ERC 爱因斯坦洛克菲勒纽约市立大学艾滋病研究中心

• 批准号: 10605257
• 负责人: HARRIS GOLDSTEIN
• 金额: $ 54.93万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-05-01 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10605257
• 关键词: Acceleration; Acquired Immunodeficiency Syndrome; Advisory Committees; Behavioral; Clinical; Collaborations; Communication; Communities; County; Development; Education; Electronic Mail; Ensure; Epidemic; Epidemiology; Faculty; Fostering; Funding; Goals; Grant; Growth; HIV; HIV Infections; HIV diagnosis; Health; Infrastructure; Institution; Interdisciplinary Study; International; Lead; Leadership; Location; Medicine; Mental Health; Monitor; New York City; Newsletter; Occupational activity of managing finances; Outcome; Outcome Measure; Paper; Performance; Process; Productivity; Public Health Schools; Publications; Recommendation; Research; Research Personnel; Research Priority; Resources; Scientific Advances and Accomplishments; Strategic Planning; Structure; Surveys; Training; United States; United States National Institutes of Health; Universities; Update; career; college; implementation process; improved; meetings; member; multidisciplinary; novel strategies; novel therapeutics; prevent; programs; recruit; response; sound; success; synergism; uptake; web site; working group

PROJECT SUMMARY ERC-CFAR: ADMINISTRATIVE CORE (AC) The continued location of New York City (NYC) as an epicenters of the HIV epidemic, with four of the 48 counties with the highest number of new HIV diagnoses targeted by the Ending the HIV Epidemic in the U.S. (EHE) plan, makes NYC is an essential location for leveraging the capacity of a CFAR to mobilize, lead, and coordinate the multidisciplinary research response required to achieve the EHE goal of ending the HIV epidemic in the United States within 10 years. The Einstein/Rockefeller/CUNY (ERC)-CFAR, led by the Administrative Core (AC), brings together, synergizes and focuses researchers from the Albert Einstein College of Medicine (Einstein), Rockefeller University (Rockefeller), and CUNY School of Public Health/Hunter College (CUNY), as well as from the NYC Department of Health and Mental Hygiene (NYC DOHMH) on the overarching goal of stopping new HIV infections. The Administrative Core (AC) coordinates ERC- CFAR resources and activities to enable the collective ERC-CFAR research community to accelerate their research developing novel strategies to increase uptake of current treatments and discovering new approaches to prevent, treat, and functionally cure HIV. The AC guides the ERC-CFAR using a Strategic plan which is updated annually in a process that integrates input from our Executive, Steering, Internal and External Scientific Advisory Committees, and Community Participatory Partnership and an annual membership survey. An metric indicating our success during the previous funding period is a 30% increase in our OAR FRB from ~$34M to ~$44.7M and the publication by ERC-CFAR investigators of over 1,250 papers. We have obtained an increased annual institutional commitment of $620K ($3.1 million over five years) from the Einstein, Rockefeller, and CUNY leadership to further expand our activities. The AC provides sound and dynamic financial management of the ERC-CFAR with the agility to reallocate funds and realign Cores and Scientific Working Groups (SWGs) to support emerging high-priority research directions from OAR/NIH initiatives and recommendations from our Internal and External Scientific Advisory Boards. This is accomplished through the following four Specific Aims: 1) To develop and implement a strategic planning process that will quantitatively and qualitatively increase and improve collaborative, trans-institutional, interdisciplinary, and translational HIV research among Einstein, Rockefeller, and CUNY investigators; 2) To utilize a responsive and inclusive scientific leadership structure, Cores, and a SWG to drive synergism among Einstein, Rockefeller, and CUNY investigators, and to coordinate and expand the investigative and educational HIV activities at Einstein, Rockefeller, and CUNY; 3) To promote interactions of ERC- CFAR investigators with other inter-CFAR activities and with NYC; and 4) To utilize outcome measures to monitor success in meeting ERC-CFAR goals and programs.

项目概要 ERC-CFAR：管理核心 (AC) 纽约市 (NYC) 仍然是艾滋病毒流行的中心，其中四个城市 终结艾滋病毒目标的 48 个新发艾滋病毒确诊人数最多的县 美国疫情（EHE）计划使纽约成为发挥产能的重要地点 CFAR 的职责是动员、领导和协调多学科研究响应，以实现 实现在 10 年内结束美国艾滋病毒流行的 EHE 目标。这 爱因斯坦/洛克菲勒/纽约市立大学 (ERC)-CFAR，由行政核心 (AC) 领导，汇集了： 协同并集中来自阿尔伯特·爱因斯坦医学院（Einstein）的研究人员， 洛克菲勒大学（Rockefeller）和纽约市立大学公共卫生学院/亨特学院（CUNY）， 以及纽约市健康和心理卫生局 (NYC DOHMH) 的 阻止新的艾滋病毒感染的总体目标。行政核心 (AC) 协调 ERC- CFAR 资源和活动使 ERC-CFAR 研究社区能够 加速他们的研究，开发新策略以增加对当前治疗方法的采用 发现预防、治疗和功能性治愈艾滋病毒的新方法。 AC 引导 ERC-CFAR 使用战略计划，该计划每年在整合输入的过程中更新 来自我们的执行、指导、内部和外部科学咨询委员会，以及 社区参与伙伴关系和年度会员调查。表明我们的指标 上一个资助期间的成功是我们的 OAR FRB 增加了 30%，从约 3400 万美元增加到 约 4,470 万美元，以及 ERC-CFAR 研究人员发表的 1,250 多篇论文。我们已经获得了 年度机构承诺增加 62 万美元（五年 310 万美元） 爱因斯坦、洛克菲勒和纽约市立大学的领导进一步扩大了我们的活动。空调提供 对 ERC-CFAR 进行健全、动态的财务管理，并能够灵活地重新分配资金 并重新调整核心和科学工作组（SWG）以支持新兴的高优先级 OAR/NIH 倡议的研究方向以及我们内部和外部的建议 科学顾问委员会。这是通过以下四个具体目标来实现的： 1) 制定并实施战略规划流程，从数量和质量上 增加和改善协作、跨机构、跨学科和转化艾滋病毒 爱因斯坦、洛克菲勒和纽约市立大学研究人员之间的研究； 2）利用响应式和 包容性的科学领导结构、核心和 SWG 来推动爱因斯坦之间的协同作用， 洛克菲勒和纽约市立大学的调查人员，并协调和扩大调查范围 爱因斯坦、洛克菲勒和纽约市立大学的艾滋病毒教育活动； 3）促进ERC-的互动 CFAR 调查员与其他 CFAR 之间的活动以及与纽约市的合作； 4) 利用成果 监控 ERC-CFAR 目标和计划是否成功实现的措施。