PATHOGENESIS AND GENE THERAPY IN GM2-GANGLIOSIDOSIS

GM2 神经节节病的发病机制和基因治疗

• 批准号: 3414164
• 负责人: EDWARD A. NEUWELT
• 金额: $ 20.62万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-04-01 至 1993-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3414164
• 关键词: DNA; Escherichia coli; Herpesviridae; Sandhoff disease; beta N acetylhexosaminidase; beta galactosidase; blood brain barrier; cats; chromosome deletion; chromosome disorders; complementary DNA; disease /disorder model; fibroblasts; gene expression; gene therapy; genetic library; genetic manipulation; genome; ligase; lysosomes; messenger RNA; molecular cloning; molecular genetics; molecular pathology; pathology; polymerase chain reaction; protein biosynthesis; protein sequence; transfection; transposon /insertion element; DNA; Escherichia coli; Herpesviridae; Sandhoff disease; beta N acetylhexosaminidase; beta galactosidase; blood brain barrier; cats; chromosome deletion; chromosome disorders; complementary DNA; disease /disorder model; fibroblasts; gene expression; gene therapy; genetic library; genetic manipulation; genome; ligase; lysosomes; messenger RNA; molecular cloning; molecular genetics; molecular pathology; pathology; polymerase chain reaction; protein biosynthesis; protein sequence; transfection; transposon /insertion element

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