ADOLESCENT DEVELOPMENT AND STD ACQUISITION IN FEMALES

女性青少年发展和性病感染

• 批准号: 2070467
• 负责人: Susan L Rosenthal
• 金额: $ 10.29万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-08-01 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2070467
• 关键词: adolescence (12-20); child physical development; child psychology; communicable disease diagnosis; communicable disease transmission; coping; female; female reproductive system disorder diagnosis; health behavior; human subject; interview; longitudinal human study; psychosexual development; sex behavior; sexually transmitted diseases; social behavior

Introduction: Sexually transmitted diseases (STUD) are a significant public health problem, especially among adolescents. In order to plan effective interventions for adolescents, longitudinal studies need to be conducted that will aid in the understanding of the psychological and behavioral issues that underlie the initial STD acquisition as well as the responses of the adolescent following acquisition. Aims: The first aim is to examine the complex relationships of the components of adolescent development to adolescent girl's sexual behavior and the consequences of sexual behavior on adolescent girls. Components of adolescent development include: cognitive, psychosexual, and biological maturation, knowledge and perceptions, sociocultural context, and the adolescent's ability to manage situations. The second aim is to examine, longitudinally, the relationship of the developmental changes in psychological development and sexual practices for adolescent girls. This aim will examine changes in adolescents' beliefs and behaviors after they acquire or do not acquire an STD. Methods: One hundred and seventy-five adolescent girls, ages 12-15, will be recruited from their source of primary care in an urban adolescent clinic. The sample will consist of a racially mixed cohort, with both sexually inexperienced and experienced girls. They will be evaluated every 6 months for three years. At each 6-month visit, psychological/behavioral data will be collected by interview and standardized assessment measures. The sexually experienced subjects will receive a pelvic exam and Pap smear, and standard procedures will be used for the diagnosis of trichomonas, gonorrhea, and Chlamydia infections. Once yearly, a polymerase chain reaction assay for human papillomavirus will be performed and blood will be obtained for syphilis serology and herpes simplex virus serotyping. Confidential testing for human immunodeficiency virus will occur at the beginning and the end of the study. Subjects with positive results will be referred to their primary care provider. Medical charts will be reviewed to document any STD that occurs between study appointments. Clinical Significance: Behavioral/psychological strategies will continue to be the fundamental approach to the prevention of sexually transmitted diseases in adolescents. This longitudinal study will provide data regarding adolescent development across the adolescent age span and levels of sexual experience. The adolescent's style of coping as it relates to her perception of sexually transmitted diseases will be characterized. This study will improve our understanding of adolescents who place themselves at risk for sexually transmitted diseases.

简介：性传播疾病（螺柱）是重要的 公共卫生问题，尤其是在青少年中。 为了计划 对青少年的有效干预措施，纵向研究必须是 进行的将有助于理解心理和 最初收购的行为问题以及 收购后青少年的反应。 目的：第一个目的是检查 青春期女孩的性行为的青少年发展的组成部分 以及性行为对青少年女孩的后果。 组件 青少年发展包括：认知，心理和生物学 成熟，知识和看法，社会文化背景以及 青少年管理情况的能力。 第二个目的是检查， 纵向地，发展变化的关系 青少年女孩的心理发展和性习俗。 这 AIM将检查青少年的信念和行为的变化之后 获取或不收购性病。 方法：12-15岁的一百七十五岁的青少年女孩将 在城市青少年的初级保健来源招募 诊所。 样本将由种族混合的队列组成，两者都 性不足和经验丰富的女孩。 他们将每次评估 三年6个月。 在每六个月的访问中，心理/行为 数据将通过访谈和标准化评估措施收集。 性经验丰富的学科将接受骨盆检查和子宫颈抹片检查， 和标准程序将用于诊断毛毛虫的诊断， 淋病和衣原体感染。 每年一次，聚合酶链 将进行人乳头瘤病毒的反应测定，血液将是 获得梅毒血清学和单纯疱疹病毒血清分型的获得。 人类免疫缺陷病毒的机密测试将发生在 开始和研究结束。带有积极结果的受试者将是 转交给其初级保健提供者。 医疗图表将进行审查 记录研究任命之间发生的任何性病。 临床意义：行为/心理策略将继续 成为预防性传播的基本方法 青少年疾病。 这项纵向研究将提供数据 关于整个青少年年龄跨度和水平的青少年发展 性经验。 青少年的应对方式与 她对性传播疾病的看法将被描述。 这项研究将提高我们对位置的青少年的理解 自己有性传播疾病的风险。