Biostatistics and Research Design Shared Resource

生物统计学和研究设计共享资源

基本信息

批准号：
10627042
负责人：
Sara Katherine Vesely
金额：
$ 13.94万
依托单位：
UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-05-01 至 2028-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10627042
关键词：
Accounting Area Basic Science Bioinformatics Biometry Biostatistical Methods Cancer Center Cancer Center Support Grant Centers of Research Excellence Charge Cherokee Indian Clinical Cancer Center Clinical Investigator Clinical Research Clinical Sciences Clinical Trials Clinical Trials Design Complex Conceptions Consultations Data Data Analyses Data Collection Databases Development Doctor of Philosophy Educational process of instructing Enrollment Ensure Epidemiology Faculty Funding Future Genetic Goals Grant Growth Knowledge Machine Learning Malignant Neoplasms Manuscripts Mentors Meta-Analysis Methods Monitor Observational Study Oklahoma Outcome Peer Review Phase Phase I Clinical Trials Pilot Projects Play Postdoctoral Fellow Preparation Productivity Protocols documentation Random Allocation Reporting Reproducibility Research Research Activity Research Design Research Personnel Resource Sharing Resources Retrospective Studies Review Committee Role Safety Sample Size Sampling Scheme Services Site Statistical Data Interpretation Statistical Methods Students Surveys Training and Education Translating Translational Research United States National Institutes of Health Work Writing anticancer research community based participatory research cost efficient data integration design doctoral student education research experimental study genetic analysis innovation investigator-initiated trial member multiple data sources novel phase I trial phase II trial pilot trial primary endpoint programs randomized, clinical trials recruit research to practice student training systematic review translational cancer research undergraduate student web page

项目摘要

BIOSTATISTICS AND RESEARCH DESIGN SHARED RESOURCE: ABSTRACT The Biostatistics and Research Design Shared Resource (BRD SR) plays a critical role in research activities at the Stephenson Cancer Center (SCC) through supporting biostatistical and research design needs for SCC members. The BRD SR is directed by Sara Vesely, PhD (CPC) and co-directed by Daniel Zhao, PhD (CT), and has seven PhD-level faculty and six staff. The BRD SR provides biostatistical and research design assistance for a variety of projects, including basic science experiments, meta-analyses, secondary data analysis, genetic data and bioinformatics analysis, observational studies, qualitative studies, community research, pilot trials, randomized clinical trials, and phase I investigator-initiated trials (IITs). Major consultative services provided by BRD SR faculty include assistance with refining aims and outcomes, appropriate study design selection, data collection planning, development of statistical analysis and data monitoring plans, creation of random allocation schemes, sample size calculations, and grant preparation. The BRD SR is a cost-efficient resource to assist SCC members in a timely manner, free of direct charge, through project conception, development, grant writing, implementation, analysis, and manuscript writing. Services can be accessed online via the SCC / BRD SR webpages, with an online service request form. BRD SR faculty and staff have a diverse set of expertise, including database creation and management, research design, biostatistical analysis, statistical genetics analysis, geo-spatial methods, sampling strategies and weighting, data monitoring, and grant writing. In 2021, 57 total SCC members utilized the BRD SR, accounting for 73% of BRD SR usage. SCC members with peer-reviewed support (n=41) accounted for 53% of the total usage. In 2021, the BRD SR supported over 140 cancer-focused SCC projects (ongoing grants, IITs, and other projects) and 105 grant submissions (submissions and resubmissions). From 2017 to 2021, the BRD SR provided biostatistical consultation services to 80 full and associate members across all three SCC programs. The number of SCC member users has steadily increased each year – 36 (2017), 44 (2018), 46 (2019), 50 (2020), 57 (2021) – a 58% increase in annual SR usage from the beginning to the end of the reporting period. Future plans are focused on the addition of faculty (2-4) and staff (2-4) biostatisticians over the next five years, expertise to be determined by SCC strategic growth and needs, and to be recruited in partnership with the Department of Biostatistics and Epidemiology.

生物统计学和研究设计共享资源：摘要生物统计学和研究设计共享资源（BRD SR）在研究活动中起着至关重要的作用斯蒂芬森癌症中心（SCC）通过支持SCC的生物统计和研究设计需求成员。并拥有七个博士学位和六名员工。帮助各种项目，包括基础科学实验，荟萃分析，次要数据分析，遗传数据和生物信息学分析，观察研究，定性研究，社区研究，试验试验，随机临床试验和I期研究者发起的试验（IIT）。 BRD SR教职员工提供的服务，以探讨目标和结果，适当的研究设计选择，数据收集计划，统计分析和数据监视计划的开发，创建随机分配方案，样本量计算和授予预备。 BRD SR是一种经济高效的资源，可及时协助SCC成员，免费收费，通过项目概念，发展，授予写作，实施，分析和手稿写作。可以通过在线服务请求表中通过SCC / BRD SR网页在线访问服务 SR教职员工拥有多种专业知识，包括数据库创建和管理，研究设计，生物统计分析，统计遗传学分析，地理空间方法，采样策略和加权，数据监视和授予写作。对于BRD SR使用的73％。使用。项目和105个赠款提交（提交和重新提交）。在所有三个SCC计划中为80名全面成员提供了生物统计咨询服务。 SCC用户的数量已稳步增加-36（2017），44（2018），46（2019），50 （2020），57（2021） - 从报告期开始到结束时，年度使用率增加了58％。未来计划的重点是增加教职员工（2-4）和工作人员（2-4）生物群体主义者五年由SCC的战略增长和需求确定的专业知识，并与该公司合作招募。生物统计学和流行病学系。