Harvard Systems Biology Graduate Program

哈佛系统生物学研究生项目

• 批准号: 10621381
• 负责人: Timothy J Mitchison
• 金额: $ 31.83万
• 依托单位: HARVARD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10621381
• 关键词: Systems Biology; programs

Project Summary/abstract This application requests support for the PhD Program in Systems Biology at Harvard University. This profoundly interdisciplinary program attracts top students with backgrounds ranging from pure mathematics to medicine, and offers them the resources and support to develop an independent and quantitative approach to important biological questions. The Systems Biology program integrates systems biology research across the whole of Harvard University, including Harvard's main (Cambridge) campus and the basic science departments of Harvard Medical School (HMS) and its teaching hospitals, creating a genuinely unified cross-Harvard program that encourages student creativity and choice of both research area and of future career. The behavior of biological systems is complex and often unpredictable, in ways that profoundly challenge our ability to diagnose and treat diseases or understand the behavior of the world around us. We believe that students who have a deep understanding of both quantitative measurement technologies and mathematical or computational approaches will develop creative new ways to grapple with the complexity of biological systems. The program is also a major vehicle for bringing quantitative and theoretical approaches into problems relevant to the clinic. Since the last submission of this grant, the program has made major strides towards a representative student population: this year, for the first time, female scientists are in the majority in the entering cohort of 8 women and 3 men and applications from underrepresented minorities doubled in 2017-18 compared to previous years. The average time to degree is 5.4 years. The previous grant supported 6 trainees. In this funding period we request support for 8 trainees. The Harvard Systems Biology PhD Program is a pioneering program and an ongoing experiment. The program aims to help students identify biological questions to which an interdisciplinary approach can provide uniquely satisfying answers, and to prepare them to identify and address such questions in their future careers. The program pays particular attention to rigor and reproducibility, training students in the physicochemical basis of the measurements they make and in appropriate techniques, and common pitfalls, in statistical analysis. Training for communication across disciplines and to the lay public is foundational for the Program and is emphasized throughout each student's career.

项目概要/摘要 此申请请求哈佛大学系统生物学博士项目的支持。这 深刻的跨学科课程吸引了具有从纯数学到数学背景的顶尖学生 医学，并为他们提供资源和支持，以开发独立和定量的方法 重要的生物学问题。系统生物学项目整合了整个系统生物学研究 整个哈佛大学，包括哈佛大学主校区（剑桥）和基础科学系 哈佛医学院 (HMS) 及其教学医院，创建真正统一的跨哈佛 鼓励学生创造力以及对研究领域和未来职业的选择的计划。 生物系统的行为是复杂且常常不可预测的，这深刻地挑战着我们的 诊断和治疗疾病或了解我们周围世界的行为的能力。我们相信 对定量测量技术和数学或数学有深刻理解的学生 计算方法将开发出创造性的新方法来应对生物系统的复杂性。 该计划也是将定量和理论方法引入相关问题的主要工具 到诊所。 自上次提交这笔补助金以来，该计划在成为代表性学生方面取得了重大进展 人口：今年，在 8 名女性科学家中，女性科学家首次占多数 与前几年相比，2017-18 年，男性和 3 名男性以及代表性不足的少数族裔的申请数量增加了一倍。 获得学位的平均时间为 5.4 年。先前的拨款资助了 6 名学员。在本次资助期间我们 请求为 8 名学员提供支持。 哈佛系统生物学博士项目是一项开创性项目，也是一项正在进行的实验。该计划 旨在帮助学生识别跨学科方法可以提供独特的生物学问题 令人满意的答案，并帮助他们在未来的职业生涯中识别和解决这些问题。这 该计划特别注重严谨性和可重复性，培训学生的物理化学基础 他们在统计分析中采用适当的技术进行测量，以及常见的陷阱。 跨学科和面向公众的沟通培训是该计划的基础， 在每个学生的职业生涯中都强调。