Measuring Chronic Pain Impact

测量慢性疼痛的影响

基本信息

批准号：
10609108
负责人：
RONALD Dale HAYS
金额：
$ 16.85万
依托单位：
RAND CORPORATION
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-02-15 至 2024-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10609108
关键词：
Address Administrative Supplement Anxiety Area Clinical Clinical Research Clinical effectiveness Collaborations Collection Complex Coupled Data Data Collection Data Sources Ensure Evaluation Factor Analysis Fatigue Frequencies Future General Population Goals Grant Health Individual Information Systems Intervention Libraries Measurement Measures Mental Depression Mental Health Monitor National Center for Complementary and Integrative Health Outcome Pain Pain interference Patient Outcomes Assessments Patients Performance Persons Physical Function Psychometrics Research Personnel Sleep disturbances Social Role-Participation Standardization Statistical Data Interpretation Surveys Treatment Effectiveness Work base behavioral health chronic pain clinical care clinical practice cognitive function cost effectiveness expectation health care delivery health care service individual patient interest parent grant patient-clinician communication physical conditioning preference response shared decision making sound theories

项目摘要

Summary/Abstract Collection of individual patient-reported outcome (PRO) data in clinical contexts is increasing and has been shown to enhance clinician-patient communication. It can be used to identify patient priorities and preferences, set treatment expectations, and support shared decision-making. At an aggregate level, PROs can be used to examine the clinical- and cost-effectiveness of treatments, measure and monitor quality, and optimize planning and delivery of healthcare services. The Patient-Reported Outcome Measurement Information System (PROMIS®) measures are attractive for use in clinical settings because of their psychometric soundness, straightforward interpretation, and standardized metrics normed to the general population. However, the existing PROMIS Profile measures are burdensome for routine clinical use, leading many to opt for shorter more limited measures within or outside the PROMIS library. Our overarching goal is to plan and conduct complex statistical analyses, including item response theory analyses to fill this gap by identifying a brief and psychometrically sound measure that future researcher can use to examine impacts of their interventions on whole person health outcomes that matter most to patients. Specifically, we propose to develop a Short PROMIS Profile measure (SPP) that can: 1) efficiently produce scores for eight health domains (i.e., physical function, pain interference, fatigue, sleep disturbance, depression, anxiety, social role participation, cognitive function); 2) generate physical and mental health summary scores; and 3) calculate the PROMIS preference (PROPr) score. Our approach includes ongoing input from invested stakeholders who will work closely with the study to ensure broad buy-in for the resulting SPP. Through our work on the parent grant, our study team has identified 50 unique PROMIS items for possible inclusion in the SPP and has access to a data source that includes responses to all candidate items. We will conduct analyses using the existing data and arrive at an optimal SPP through completion of the following specific aims: 1. Construct several candidate SPPs by identifying and combining optimally performing two-item sets for each of the 8 PROMIS domains being considered for inclusion in the SPP; 2. Reduce and refine the number of candidate measures based on: a) performance of general physical and mental health summary scores derived from factor analysis; and b) evaluation of candidate profile measures’ estimated PROPr scores; and 3. Select the final SPP specification in collaboration with the stakeholder group based on results from Aim 2. At the completion of these three aims we will have a robust SPP that can be included in the PROMIS library and made available for general use. The availability of this measure has the potential to significantly impact the frequency and usefulness of routine PRO data collection in clinical care and will also enable behavioral health researchers and clinical trialists to include a robust PROMIS scale in their surveys without excessive burden or loss in precision.

摘要/摘要临床环境中个体患者报告结果 (PRO) 数据的收集正在增加，并且已经它可以用来增强临床医生与患者的沟通，以确定患者的优先事项和偏好， PRO 可用于设定治疗期望并支持共同决策。检查治疗的临床和成本效益，测量和监控质量，并优化计划和提供医疗服务。患者报告的结果测量信息系统。 (PROMIS®) 措施因其心理测量的可靠性而在临床环境中使用很有吸引力，简单的解释和针对一般人群的标准化指标。现有的 PROMIS Profile 测量对于常规临床使用来说是繁重的，导致许多人选择较短的测量 PROMIS 图书馆内外的措施更为有限。我们的总体目标是规划和实施。复杂的统计分析，包括项目反应理论分析，通过确定一个未来的研究人员可以使用简短且可靠的心理测量方法来检查其影响具体来说，我们建议对患者最重要的整体健康结果进行干预。开发一个简短的 PROMIS 概况测量 (SPP)，它可以：1) 有效地为八项健康状况生成分数领域（即身体功能、疼痛干扰、疲劳、睡眠障碍、抑郁、焦虑、社会角色参与、认知功能）；2）生成身心健康总结分数；3）计算 PROMIS 偏好 (PROPr) 评分我们的方法包括来自投资利益相关者的持续投入。通过我们在家长补助金方面的工作，与该研究密切合作，以确保获得广泛的支持。我们的研究团队已确定 50 个独特的 PROMIS 项目可能包含在 SPP 中，并且可以访问数据源，包括对所有候选项目的答复，我们将使用现有数据进行分析。并通过完成以下具体目标得出最佳 SPP： 1. 构造几个候选 SPP 通过识别和组合 8 个 PROMIS 域中每一个域的最佳性能两项集来实现考虑纳入 SPP； 2. 根据以下因素减少和细化候选措施的数量： a) 通过因子分析得出的一般身心健康总结分数；以及 b) 评估候选配置文件测量的估计 PROPr 分数；以及 3. 选择最终的 SPP 规范根据目标 2 的结果与利益相关者团体进行合作。在完成这三个目标后，我们将拥有一个强大的 SPP，可以包含在 PROMIS 库中并可供一般使用。这项措施的可用性有可能显着影响日常活动的频率和有效性临床护理中的 PRO 数据收集也将使行为健康研究人员和临床试验人员能够在他们的调查中包含强大的 PROMIS 量表，而不会造成过多的负担或精度损失。

项目成果

期刊论文数量（22）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Classifying patients with non-specific chronic low back pain using the impact stratification score in an online convenience sample.

DOI：
10.1186/s12891-023-06848-2
发表时间：
2023-09-09
期刊：
BMC MUSCULOSKELETAL DISORDERS
影响因子：
2.3
作者：
Rodriguez, Anthony;Herman, Patricia M.;Slaughter, Mary E.;Edelen, Maria Orlando;Hays, Ron D.
通讯作者：
Hays, Ron D.

Using Item Response Theory to Identify Responders to Treatment: Examples with the Patient-Reported Outcomes Measurement Information System (PROMIS®) Physical Function Scale and Emotional Distress Composite.

DOI：
10.1007/s11336-021-09774-1
发表时间：
2021-09
期刊：
Psychometrika
影响因子：
3
作者：
Hays RD;Spritzer KL;Reise SP
通讯作者：
Reise SP

Longitudinal Associations of PROMIS-29 Anxiety and Depression Symptoms With Low Back Pain Impact in a Sample of U.S. Military Service Members.

PROMIS-29 焦虑和抑郁症状与美国军人样本中腰痛影响的纵向关联。

DOI：
10.1093/milmed/usab339
发表时间：
2023
期刊：
Military medicine
影响因子：
1.2
作者：
Dunbar,MichaelS;Rodriguez,Anthony;Edelen,MariaO;Hays,RonD;Coulter,IanD;Siconolfi,Daniel;Herman,PatriciaM
通讯作者：
Herman,PatriciaM

Definitions of Chronic Low Back Pain From a Scoping Review, and Analyses of Narratives and Self-Reported Health of Adults With Low Back Pain.

DOI：
10.1016/j.jpain.2022.10.012
发表时间：
2023-03
期刊：
JOURNAL OF PAIN
影响因子：
4
作者：
Herman, Patricia M.;Qureshi, Nabeel;Arick, Susan D.;Edelen, Maria O.;Hays, Ron D.;Rodriguez, Anthony;Weir, Rebecca L.;Coulter, Ian D.
通讯作者：
Coulter, Ian D.

Estimating individual health-related quality of life changes in low back pain patients.