Methods Core

方法核心

• 批准号: 10577119
• 负责人: CATARINA I. KIEFE
• 金额: $ 81.96万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-05 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10577119
• 关键词: Acceleration; Adoption; Applications Grants; Articulation; Artificial Intelligence; Award; Biometry; Caring; Cellular Phone; Clinical Research; Clinical Trials; Collaborations; Common Data Element; Complement; Computers; Data; Data Science; Dimensions; Discipline; Early Diagnosis; Effectiveness; Engineering; Ensure; Epidemiology; Evaluation; Extramural Activities; Faculty; Family; Fostering; Funding; Goals; Health Services Research; Health system; Healthcare; Incubators; Individual; Industrialization; Knowledge; Leadership; Learning; Logic; Machine Learning; Measurement; Methodology; Methods; Modeling; Monitor; Patients; Physicians; Pilot Projects; Predictive Analytics; Production; Psychometrics; Public Health; Quasi-experiment; Randomized, Controlled Trials; Reporting; Research; Research Activity; Research Design; Research Project Grants; Resources; Rest; Science; Scientist; Societies; Specialist; Statistical Computing; Suicide; Suicide prevention; Technology; Telephone; Testing; Training Activity; Translational Research; Translations; Vendor; Vision; Voice; Work; advanced analytics; clinical care; clinical practice; computerized; data acquisition; design; economic evaluation; effectiveness/implementation hybrid; efficacy study; health economics; implementation design; implementation framework; implementation research; implementation science; implementation study; improved; innovation; machine learning algorithm; member; novel; operation; person centered; statistical and machine learning; suicidal risk; synergism; technological innovation; technology development; translational approach

CAPES METHODS CORE: PROJECT SUMMARY/ABSTRACT Significance: The CAPES Methods Core has dual goals of: (1) supporting transdisciplinary team science for all CAPES research by providing methodological expertise and technical support, and (2) serving as an incubator for generating new methods in practice-based suicide prevention care technology and implementation research. The Core’s significance rests on a combination of: (a) state-of-the-art methods built into the four proposed projects that support their individual scientific and public health impact, (b) opportunities for the Methods Core to synthesize data and learnings across projects, and (c) advancement of methods for suicide research. Innovation: The Methods Core will innovate through: (1) building and applying innovative, highly efficient implementation study designs, (2) fostering a common implementation science framework and measurement, (3) exploring the synergy between classical statistical and machine learning analytic approaches, and (4) innovating suicide care technology development and user testing. Approach: The Methods Core will be co-led by a physician-scientist and methodologist (Kiefe, CAPES Co- Directors), a computer scientist and engineer (Agu), and a biostatistician and psychometrician (Yang). Core faculty have expertise in implementation science, biostatistics, psychometrics, epidemiology, health economics, health services research, person-centered design, artificial intelligence, machine learning, and healthcare industrial engineering. The Core is organized into six Units, and Core scientists are embedded into each project team. The Core has the following Specific Aims: Aim 1. Provide methodological expertise and technical support to all CAPES projects. Aim 2. Advance analytic and implementation methods to study adoption of technologies and methods enabling improved practice-based suicide-related research and care. Example: Innovative design of the Signature Project, which will be an Efficacy/Effectiveness/Implementation hybrid. Aim 3. Create guidance on best practices in health system adoption of technologies that enable suicide care and operationalize how the technologies can facilitate adoption through cross-project knowledge aggregation. Example: production of the EHR Best Practice Guide to Implementing Zero Suicide for EHR vendors and health systems. Aim 4. Together with the Administrative Core, evaluate all CAPES research and training activities and broadly disseminate CAPES findings, methodological advances, and other resources based on a Logic Model for evaluation and multi-channel dissemination approaches to diverse stakeholders. Impact: CAPES in general, and the Methods Core in particular, will transform the way that technology is used to aid and augment suicide prevention clinical practice and research. The Methods Core will also become a national resource for the implementation of suicide prevention-related technology.

CAPES 方法核心：项目摘要/摘要 意义：CAPES 方法核心具有双重目标：(1) 支持所有人的跨学科团队科学 通过提供方法学专业知识和技术支持进行 CAPES 研究，以及 (2) 作为孵化器 产生基于实践的自杀预防护理技术和实施研究的新方法。 核心的重要性取决于以下方面的组合：(a) 四种提议中内置的最先进的方法 支持其个人科学和公共卫生影响的项目，(b) 方法核心的机会 综合各个项目的数据和经验教训，以及 (c) 自杀研究方法的进步。 创新：方法核心将通过以下方式进行创新：（1）构建和应用创新、高效 实施研究设计，(2) 建立共同的实施科学框架和衡量标准， (3) 探索经典统计和机器学习分析方法之间的协同作用，以及 (4) 创新自杀护理技术开发和用户测试。 方法：方法核心将由医师科学家和方法学家（Kiefe、CAPES Co- 董事）、计算机科学家和工程师（Agu）以及生物统计学家和心理测量学家（Yang Core）。 教师拥有科学、生物统计学、心理测量学、流行病学、卫生经济学、 健康服务研究、以人为本的设计、人工智能、机器学习和医疗保健 工业工程核心分为六个单位，每个项目都有核心科学家。 核心团队有以下具体目标： 目标 1. 为所有 CAPES 项目提供方法学专业知识和技术支持。 目标 2. 推进分析和实施方法，以研究技术和方法的采用，使 改进基于实践的自杀相关研究和护理示例：签名项目的创新设计， 这将是功效/效果/实施的混合体。 目标 3. 就卫生系统采用自杀护理技术的最佳实践制定指南 并具体化这些技术如何通过跨项目知识聚合来促进采用。 示例：为电子病历供应商和卫生部门制作实施零自杀的电子病历最佳实践指南 系统。 目标 4. 与行政核心一起评估所有 CAPES 研究和培训活动并广泛评估 传播 CAPES 的研究结果、方法论进展以及基于逻辑模型的其他资源 向不同利益相关者提供评估和多渠道传播方法。 影响：一般而言，CAPES，特别是方法核心，将改变技术的使用方式 帮助和加强自杀预防的临床实践和研究。方法核心也将成为一个。 实施自杀预防相关技术的国家资源。