TOXICOGENOMICS OF ACETAMINOPHEN HEPATOTOXICITY

对乙酰氨基酚肝毒性的毒理学

• 批准号: 7716810
• 负责人: PAUL B WATKINS
• 金额: $ 3.15万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-02 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7716810
• 关键词: Acetaminophen; Blood; Computer Retrieval of Information on Scientific Projects Database; Dose; Funding; Gene Expression; Grant; Hepatotoxicity; Human; Institution; Purpose; Research; Research Personnel; Resources; Source; Toxicogenomics; United States National Institutes of Health; day; research study; treatment duration

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to see if whether 7 days of treatment with the maximun recommended dose of acetaminophen (4g per day) will produce changes in gene expression in human blood.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究的目的是观察使用最大推荐剂量的对乙酰氨基酚（每天 4 克）治疗 7 天是否会产生人体血液中基因表达的变化。