Role of Executive Control in Adolescent Substance Use and Co-occuring Problems

执行控制在青少年药物使用和同时发生的问题中的作用

基本信息

批准号：
10239267
负责人：
W Alex Mason
金额：
$ 55.17万
依托单位：
UNIVERSITY OF TENNESSEE HEALTH SCI CTR
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2022-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10239267
关键词：
Accidents Adolescence Adolescent Age Alcohol consumption Behavior Cause of Death Child Childhood Data Development Developmental Process Dimensions Family Gender Goals Growth Factor Health Homicide Individual Individual Differences Intervention Link Longitudinal Studies Marijuana Measurement Mediating Mediator of activation protein Methods Morbidity - disease rate National Institute of Drug Abuse Nursery Schools Outcome Parents Participant Performance Plant Roots Prevention Problem Solving Problem behavior Public Health Research Risk Risk Factors Role Sampling Schools Social Development Specific qualifier value Strategic Planning Suicide Teenagers Testing Time United States National Institutes of Health Youth adolescent substance use adverse outcome base cigarette smoke cognitive ability cognitive process critical developmental period design directed attention early onset elementary school executive function innovation insight intervention refinement longitudinal design marijuana use model development modifiable risk mortality neurodevelopment peer performance based measurement prevent preventive intervention psychosocial public health relevance social substance use substance use prevention young adult

项目摘要

Project Summary Adolescent substance use is a prevalent and significant public health concern. Although gains have been made in the development of effective substance use preventive interventions, there is room for improvement. Intervention refinements must be based on additional longitudinal research of developmental precursors that emerge well before substance use onset. Deficits in executive control (EC), a set of cognitive abilities for directing attention and behavior, have been proposed as important and modifiable contributors to adolescent problem behaviors, including substance use as well as co-occurring externalizing and internalizing problems. However, the early-emerging and dynamically-unfolding role of EC in the development of substance use and related problems is not well understood. Existing research lacks a long-term, developmentally-nuanced perspective, precluding an understanding of when and how poor EC impacts substance use risk. Preschool is a time of significant EC organization. Adolescence is a time of further EC development and differentiation, and the emergence of substance use. Yet, relevant studies spanning these critical developmental periods are lacking. This application proposes to extend an ongoing study of young children and their parents followed during preschool and the elementary school years with intensive, repeated, performance-based measures of EC (along with multi-rater, multi-method assessments of a broad array of additional factors) by collecting new data at ages 14, 15, 16, and 17. The long-term goal is to guide the development and refinement of substance use preventive interventions targeting EC as a modifiable risk factor at critical points in development. The objective of the proposed research is to explicate the long-term, dynamic impact of EC on the development of substance use and co-occurring problems. The central hypotheses are that poor EC in preschool, throughout childhood, and into adolescence will be related to the onset and growth of substance use and problem co- occurrence, and that these associations will be at least partially mediated by social developmental processes. The rationale is that a nuanced, longitudinal study of EC and substance use will richly inform the timing and targets of interventions focusing on EC to prevent adolescent substance use and related problems. The specific aims are to examine the long-term impact of EC in preschool (Aim 1) as well as the development of EC throughout childhood and adolescence (Aim 2) on adolescent substance use and co-occurring internalizing and externalizing problems, testing family, school, and peer mediating mechanisms (Aim 3) and exploring gender moderation (Exploratory Aim). The proposed project is innovative in its unique leveraging of early EC data from the sample and its rigorous and multifaceted measurement of EC over critical developmental periods. The significance of this research is that it will yield an unprecedented understanding of the impact of EC on substance use, affording new insights into when and how EC has its effects and providing information for designing optimally-timed, targeted interventions to bolster EC and prevent adolescent substance use.

项目概要青少年物质使用是一个普遍且重要的公共卫生问题。虽然已经有收获在制定有效的药物使用预防干预措施方面，还有改进的空间。干预措施的改进必须基于对发育前兆的额外纵向研究，在物质使用开始之前就出现。执行控制（EC）缺陷，这是一组认知能力引导注意力和行为，已被认为是青少年的重要且可改变的贡献者问题行为，包括物质使用以及同时发生的外化和内化问题。然而，电子商务在物质使用和滥用行为发展中的早期出现和动态展开的作用相关问题还没有得到很好的理解。现有的研究缺乏长期的、细致入微的发展研究的观点，妨碍了对不良 EC 何时以及如何影响物质使用风险的理解。学前班是重要的 EC 组织的时代。青春期是 EC 进一步发展和分化的时期，物质使用的出现。然而，跨越这些关键发展时期的相关研究是缺乏。该申请建议扩大对幼儿及其父母的持续研究在学前班和小学阶段，采用强化、重复、基于表现的措施 EC（以及对广泛的附加因素的多评估者、多方法评估）通过收集新的 14、15、16、17岁的数据。长期目标是指导实质内容的开发和完善在发展的关键时刻使用针对 EC 作为可改变风险因素的预防性干预措施。这拟议研究的目的是阐明电子商务对发展的长期动态影响物质使用和同时发生的问题。中心假设是，学前班、整个童年期和青春期将与物质使用和问题的发生和发展有关发生，并且这些关联至少部分是由社会发展过程调节的。其基本原理是，对 EC 和物质使用进行细致入微的纵向研究将丰富地提供时间和信息。重点关注预防青少年药物滥用和相关问题的 EC 干预措施的目标。这具体目标是研究学前教育的长期影响（目标 1）以及学前教育的发展整个童年和青春期（目标 2）关于青少年物质使用和同时发生的内化并将问题外化，测试家庭、学校和同伴调解机制（目标 3）并探索性别节制（探索性目标）。拟议项目的创新在于其对早期 EC 的独特利用来自样本的数据及其对关键发育阶段 EC 的严格和多方面的测量期间。这项研究的意义在于，它将对影响的影响产生前所未有的认识。关于物质使用的 EC，提供关于 EC 何时以及如何产生影响的新见解，并提供信息设计最佳时机、有针对性的干预措施，以加强 EC 并防止青少年物质使用。

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Childhood executive control and adolescent substance use initiation: the mediating roles of physical and relational aggression and prosocial behavior.

童年执行控制和青少年物质使用开始：身体和关系攻击以及亲社会行为的中介作用。

DOI：
10.1080/09297049.2022.2079615
发表时间：
2023
期刊：
Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
影响因子：
0
作者：
Patwardhan,Irina;Guo,Ying;Hamburger,EmilyR;Sarwar,Saira;Fleming,CharlesB;James,TiffanyD;Nelson,JenniferMize;Espy,KimberlyAndrews;Nelson,TimothyD;Mason,WAlex
通讯作者：
Mason,WAlex

Executive Control in Early Childhood as an Antecedent of Adolescent Problem Behaviors: A Longitudinal Study with Performance-based Measures of Early Childhood Cognitive Processes.

DOI：
10.1007/s10964-020-01316-9
发表时间：
2020-12
期刊：
Journal of youth and adolescence
影响因子：
4.9
作者：
Fleming CB;Stevens AL;Vivero M;Patwardhan I;Nelson TD;Nelson JM;James TD;Espy KA;Mason WA
通讯作者：
Mason WA

A Comparison of Task-Based and Questionnaire Assessments of Executive Control Aspects in Relation to Adolescent Marijuana Initiation.

DOI：
10.26828/cannabis/2023.01.006
发表时间：
2023-02-07
期刊：
Cannabis (Albuquerque, N.M.)
影响因子：
0
作者：
通讯作者：

Associations of Early Socio-familial Stress with Maladaptive and Adaptive Functioning in Middle Childhood: Roles of Executive Control and Foundational Cognitive Abilities.

早期社会家庭压力与童年中期适应不良和适应性功能的关联：执行控制和基础认知能力的作用。

DOI：
10.1007/s11121-020-01119-1
发表时间：
2020
期刊：
Prevention science : the official journal of the Society for Prevention Research
影响因子：
0
作者：
Mason,WAlex;Fleming,CharlesB;Tomaso,CaraC;James,TiffanyD;Nelson,JenniferMize;Espy,KimberlyAndrews;Nelson,TimothyD
通讯作者：
Nelson,TimothyD

Associations of childhood executive control with adolescent cigarette and E-cigarette use: Tests of moderation by poverty level.

DOI：
10.1016/j.addbeh.2021.106923
发表时间：
2021-08
期刊：
Addictive behaviors
影响因子：
4.4
作者：
Alex Mason W;Patwardhan I;Fleming CB;Stevens AL;James TD;Nelson JM;Espy KA;Nelson TD
通讯作者：
Nelson TD