Developmental Research Program (DRP)

发展研究计划（DRP）

• 批准号: 10246337
• 负责人: Juan Fueyo
• 金额: $ 18.84万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10246337
• 关键词: Advocate; Award; Biology; Brain Neoplasms; Cells; Cellular biology; Central Nervous System Neoplasms; Clinical Research; Collaborations; Communication; Development; Disease; Ensure; Evolution; Extramural Activities; Fostering; Foundations; Funding; Goals; Guidelines; Incubators; Laboratory Research; Malignant neoplasm of brain; Molecular; Monitor; Nature; Patient-Focused Outcomes; Patients; Peer Review; Philanthropic Fund; Pilot Projects; Process; Prognosis; Program Research Project Grants; Progress Reports; Publications; Research; Research Personnel; Research Project Grants; Resources; Seeds; Selection Criteria; Source; Translational Research; Tumor Biology; United States National Institutes of Health; University of Texas M D Anderson Cancer Center; anticancer research; cancer cell; flexibility; improved; innovation; novel diagnostics; novel therapeutics; programs; recruit; success; translational approach

SUMMMARY: DEVELOPMENTAL RESEARCH PROGRAM (DRP) The specific aims of the Developmental Research Program are to: 1) Publicize the availability of start-up funds for pilot translational brain tumor research projects across a broad spectrum of available media sources. 2) Identify through this mechanism innovative projects that have significant potential for improving brain tumor therapy and prognosis, including through better understanding the biology of this disease. 3) Foster collaborative efforts among SPORE investigators and with other investigators to encourage the development of new and innovative ideas. 4) Enhance communications between SPORE leaders and outside investigators to encourage the development of innovative translational strategies in brain tumors. 5) Ensure program flexibility so that developmental projects that show promise can be: a) funded for a second or third year; b) encouraged to apply for extramural peer-reviewed funding c) expanded to become full SPORE projects. The Brain Cancer SPORE has established clear guidelines and processes for solicitation, selection, and monitoring of the Developmental Research Awards, including specific criteria for selection and funding through a peer review mechanism, and mechanisms for close monitoring of, and collaboration between the SPORE leaders and program awardees to enhance the quality of the translational research goals. In the last funding period, we initiated support of new ideas and recruited new investigators to study brain tumors, funding 31 awards, two of which contributed to the Projects of this resubmission application. The advances made by investigators in the DRP testify to the success of this program as implemented in this MDACC Brain Cancer SPORE, including publications in Nature Cell Biology, Cell, Cancer Cell, and Cancer Research, and the acquisition of additional NIH and other funding directly related to DRP projects. The DRP has become an incubator of new concepts and a cornerstone of our Brain cancer SPORE.

摘要：发展研究计划 (DRP) 发展研究计划的具体目标是： 1) 公开跨领域的转化脑肿瘤试点研究项目启动资金的可用性 广泛的可用媒体源。 2）通过这一机制识别对改善大脑具有重大潜力的创新项目 肿瘤治疗和预后，包括通过更好地了解这种疾病的生物学。 3) 促进 SPORE 研究人员之间以及与其他研究人员之间的合作，以鼓励 发展新的和创新的想法。 4) 加强 SPORE 领导和外部调查人员之间的沟通，以鼓励 开发脑肿瘤的创新转化策略。 5) 确保计划的灵活性，以便有希望的开发项目能够： a) 资助 第二年或第三年； b) 鼓励申请校外同行评审资金 c) 扩大到 成为完整的 SPORE 项目。 脑癌 SPORE 制定了明确的征集、选择和招募指南和流程 监督发展研究奖，包括通过以下方式选择和资助的具体标准 同行评审机制以及 SPORE 之间的密切监测和协作机制 领导者和项目获奖者提高转化研究目标的质量。在上一次融资中 在此期间，我们发起了对新想法的支持，并招募了新的研究人员来研究脑肿瘤，资助了 31 奖项，其中两个为本次重新提交申请的项目做出了贡献。所取得的进展 DRP 的研究人员证明该计划在本次 MDACC 脑癌中实施取得了成功 SPORE，包括《自然细胞生物学》、《细胞》、《癌细胞》和《癌症研究》中的出版物，以及 获得额外的 NIH 和其他与 DRP 项目直接相关的资金。 DRP 已成为 新概念的孵化器和我们脑癌 SPORE 的基石。