Identifying and Targeting Unique Physical Activity Determinants for Midlife Women

识别并针对中年女性独特的身体活动决定因素

基本信息

批准号：
10132374
负责人：
Danielle Arigo
金额：
$ 15.43万
依托单位：
ROWAN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-03-01 至 2023-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10132374
关键词：
Accelerometer Address Adult Adverse event Age Attention Behavioral Behavioral Research Behavioral Sciences Biological Body mass index Cardiovascular Diseases Cardiovascular Physiology Cardiovascular system Data Effectiveness Environment Event Female Goals Health Expenditures Hour Human Individual Intervention Light Exercise Manuscripts Menopause Mentored Patient-Oriented Research Career Development Award Moods National Heart, Lung, and Blood Institute Obesity Overweight Participant Patient Care Patient Self-Report Patients Peer Review Physical activity Physical assessment Physiology Primary Health Care Primary Prevention Psychology Reporting Research Research Design Research Personnel Resources Risk Risk Marker Risk Reduction Safety Scientific Advances and Accomplishments Scientist Statistical Methods Strategic Planning Symptoms Testing Time Training Training Programs Translating Translations Woman Women&apos s Health apprenticeship base cardiovascular disorder risk cardiovascular risk factor design disorder risk effectiveness evaluation evidence base experience gender difference group intervention improved innovation mHealth men middle age mobile application mortality multidisciplinary negative mood novel patient oriented peer physical inactivity post intervention programs psychosocial recruit satisfaction skills smartphone Application social statistics therapy development tool trait

项目摘要

Cardiovascular risk and mortality is uniquely elevated among midlife women due to factors such as menopause and gender differences in cardiovascular event symptom presentation. Physical activity (PA) is critical to reducing risk in midlife women; however, this group confronts distinctive psychosocial barriers to PA that rarely are addressed by existing interventions. Current evidence and the candidate’s pilot data indicate that these barriers are negative mood, body satisfaction, and social comparison (i.e., evaluating one’s PA relative to that of peers). Mobile health tools such as smartphone applications have the ability to intervene on these barriers in real time, but developing effective tools requires a sophisticated understanding of (1) when PA occurs and determinants of PA for particular individuals in their natural environments, and (2) the ability to optimize this information for mobile delivery. The proposed K23 training program will address these needs by focusing on the following training goals: ambulatory assessment of PA and its psychosocial determinants, advanced statistical methods, individual tailoring of PA programs (with an emphasis on mobile intervention development), women’s health, and cardiovascular physiology. Training will include apprenticeships and tutorials with experts in each of these topics, as well as coursework in intensive ambulatory assessment, mobile application design, and physiology. To support this plan, the proposed research will investigate PA and its determinants among midlife female primary care patients with cardiovascular risk markers. Aim 1 of this research is to examine relations between real-time psychosocial experiences (i.e., mood, body satisfaction, social comparison) and PA among at-risk midlife women (n=100, age 40-60; 27>BMI<50 with one additional cardiovascular risk marker). This will allow for further optimization of a mobile health tool tailored for midlife women. Aim 2 of this research is to refine and pilot test a novel mobile PA application tailored for at-risk midlife women (n=30, age 40-60; 27>BMI<50 with one additional CVD risk marker). Achieving these project aims will produce multiple peer-reviewed manuscripts and a strong R01 proposal focused on testing a well-informed, tailored mobile intervention for midlife women at risk for developing CVD. This research builds on the candidate’s training to date and introduces an innovative way to understand and promote PA in midlife women. The goals of this K23 program are directly responsive to NHLBI’s strategic plan, as they will allow for improved primary prevention through increased understanding of determinants of disease risk, and the proposed program will contribute to improving interventions tailored to patient needs and barriers. The excellent training, protected time, and project resources of the proposed K23 program will prepare the candidate to become a leading patient-oriented researcher with expertise in PA promotion for cardiovascular risk reduction among midlife women.

由于以下因素，中年女性的心血管风险和死亡率特别升高更年期和心血管事件症状表现的性别差异是体力活动（PA）的影响。对于降低中年女性的风险至关重要；然而，这一群体面临着独特的社会心理障碍目前的证据和候选人的试点数据很少能解决 PA 问题。表明这些障碍是消极情绪、身体满意度和社会比较（即评估一个人的 PA 相对于同龄人）。移动健康工具（例如智能手机应用程序）有能力做到这一点。实时干预这些障碍，但开发有效的工具需要复杂的技术了解 (1) PA 何时发生以及特定个体自然状态下 PA 的决定因素环境，以及 (2) 优化此信息以进行移动交付的能力。计划将通过重点关注以下培训目标来满足这些需求： PA 动态评估及其社会心理决定因素、先进的统计方法、个人定制的 PA 计划（包括强调移动干预的发展）、妇女健康和心血管生理学。将包括每个主题的专家的学徒和教程，以及以下课程：为了支持该计划，强化动态评估、移动应用程序设计和生理学。拟议的研究将调查中年女性初级保健患者的 PA 及其决定因素本研究的目标 1 是检查实时心理社会之间的关系。高危中年女性的经历（即情绪、身体满意度、社会比较）和 PA（n=100， 40-60 岁；27>BMI<50，并有一项额外的心血管风险标记）。本研究的目标 2 是优化和试点针对中年女性的移动健康工具。测试一款专为高危中年女性量身定制的新型移动 PA 应用程序（n=30，年龄 40-60；27>BMI<50，其中一个额外的 CVD 风险标记）。实现这些项目目标将产生多份经过同行评审的手稿。以及一项强有力的 R01 提案，重点是测试针对中年女性的消息灵通、量身定制的移动干预措施这项研究以候选人迄今为止的培训为基础，并引入了一项研究理解和促进中年女性 PA 的创新方式该 K23 计划的目标是直接的。响应 NHLBI 的战略计划，因为它们将通过增加了解疾病风险的决定因素，拟议的计划将有助于改善针对患者需求和障碍量身定制的干预措施出色的培训、受保护的时间和项目。拟议的 K23 计划的资源将使候选人做好准备，成为领先的以患者为导向的人研究员，在促进 PA 促进中年女性降低心血管风险方面拥有专业知识。