Optimizing Bilateral and Single-Sided Deafness Cochlear Implants for Functioning in Complex Auditory Environments

优化双侧和单侧耳聋人工耳蜗植入物以在复杂的听觉环境中发挥作用

基本信息

  • 批准号:
    10065502
  • 负责人:
  • 金额:
    $ 36.75万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-12-01 至 2023-11-30
  • 项目状态:
    已结题

项目摘要

ABSTRACT: The vast majority of the roughly 100,000 cochlear-implant (CI) users have severe-to-profound hear- ing loss, but only receive a single CI in one ear. Yet, not having access to sound in two ears severely hampers the auditory systems' ability to overcome background noise, which has many consequences including increasing the amount of effort it takes to communicate. Even with access to sound in both ears, two-ear or “binaural” benefits for bilateral CI (BI-CI) and single-sided deaf CI (SSD-CI) users are small compared to normal-hearing listeners. Because of possible frequency mismatch between the two ears, it is unclear if the current standard approach of programming the CIs maximizes speech understanding for two ears, particularly in environments with multiple sound sources. Our long-term goal is to understand and maximize speech understanding and bin- aural benefits imparted by CIs by improving interaural frequency, level, and timing encoding. The next steps toward this goal and the objectives here are to evaluate interaural frequency mismatch and to develop novel CI programs (MAPs) to correct for mismatch. Our central hypothesis is that binaural function in BI-CI and SSD-CI users is suboptimal because of interaural frequency mismatch. Our approach will be to optimize the frequency- allocation in the poorer ear to minimize the mismatch and potentially improve speech understanding and spatial hearing. With strong preliminary data in hand, the central hypothesis will be tested by pursuing three specific aims: (1) Assess interaural frequency mismatch for individual electrodes in BI-CI and SSD-CI users. (2) Compare the acute functional benefits and limitations for the standard MAP and novel MAPs that minimize interaural fre- quency mismatch in BI-CI and SSD-CI users. (3) In a longitudinal study, evaluate the extent to which standard MAP and novel MAPs cause changes in pitch processing, binaural processing, and speech understanding in BI- CI and SSD-CI users. The expected outcome is improved binaural function for BI-CI and SSD-CI users, without sacrificing speech understanding. This research is significant because it will produce a positive impact in CI users' quality of life by improving communication in quiet and noisy environments. This proposal is innovative because it uses knowledge of binaural neural processing to provide a novel, non-invasive, and inexpensive method to reprogram CIs for bilateral hearing.
摘要:大多数大约100,000名人工耳蜗(CI)使用者中的绝大多数人都有严重的听觉 - 损失,但仅在一只耳朵中获得一个CI。但是,在两只耳朵中无法访问声音很大程度上会受伤 听觉系统能够克服背景噪声的能力,这有许多后果,包括增加 交流所需的努力。即使在两只耳朵,两口或“双耳”的耳朵中都可以使用声音 与正常听力相比,双边CI(BI-CI)和单面聋(SSD-CI)的好处很小 听众。由于两个耳朵之间可能的频率不匹配,因此尚不清楚当前标准是否是 编程CIS的方法最大化两只耳朵的语音理解,尤其是在环境中 具有多个声源。我们的长期目标是了解和最大化语音理解和bin- CI通过改善交互式频率,级别和定时编码所带来的听觉益处。下一步 朝着这个目标和这里的目标是评估交互式频率不匹配并发展新颖的CI 程序(地图)以纠正不匹配。我们的中心假设是BI-CI和SSD-CI中的双耳功能 由于交互式频率不匹配,用户是次优的。我们的方法是优化频率 - 在较贫穷的耳朵中分配以最大程度地减少不匹配并有可能提高语音理解和空间 听力。掌握了强大的初步数据,将通过追求三个特定的特定假设来检验中心假设 目的:(1)评估BI-CI和SSD-CI使用者中单个电极的手段间频率不匹配。 (2)比较 标准图和新型图的急性功能益处和局限 BI-CI和SSD-CI用户中的不匹配不匹配。 (3)在一项纵向研究中,评估标准的程度 地图和新型地图会导致音调处理,双耳处理和言语理解的变化 CI和SSD-CI用户。预期的结果是改善BI-CI和SSD-CI用户的双耳功能,没有 牺牲语音理解。这项研究很重要,因为它将对CI产生积极影响 用户通过在安静和噪音环境中改善沟通来改善生活质量。该建议是创新的 因为它使用二元神经处理的知识来提供一种新颖,无创和廉价的 重新编程为双边听力的方法。

项目成果

期刊论文数量(15)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Dichotic listening performance with cochlear-implant simulations of ear asymmetry is consistent with difficulty ignoring clearer speech.
  • DOI:
    10.3758/s13414-021-02244-x
  • 发表时间:
    2021-07
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Goupell MJ;Eisenberg D;DeRoy Milvae K
  • 通讯作者:
    DeRoy Milvae K
Counting or discriminating the number of voices to assess binaural fusion with single-sided vocoders.
计算或区分声音的数量,以评估单侧声码器的双耳融合。
Effect of experimentally introduced interaural frequency mismatch on sentence recognition in bilateral cochlear-implant listeners.
  • DOI:
    10.1121/10.0017705
  • 发表时间:
    2023-04-01
  • 期刊:
  • 影响因子:
    1
  • 作者:
    Cleary, Miranda;Milvae, Kristina DeRoy;Nguyen, Nicole;Bernstein, Joshua G. W.;Goupell, Matthew J.
  • 通讯作者:
    Goupell, Matthew J.
Binaural Optimization of Cochlear Implants: Discarding Frequency Content Without Sacrificing Head-Shadow Benefit.
人工耳蜗的双耳优化:在不牺牲头影效果的情况下丢弃频率内容。
  • DOI:
    10.1097/aud.0000000000000784
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    3.7
  • 作者:
    Sheffield,SterlingW;Goupell,MatthewJ;Spencer,NathanielJ;Stakhovskaya,OlgaA;Bernstein,JoshuaGW
  • 通讯作者:
    Bernstein,JoshuaGW
Computed-Tomography Estimates of Interaural Mismatch in Insertion Depth and Scalar Location in Bilateral Cochlear-Implant Users.
  • DOI:
    10.1097/mao.0000000000003538
  • 发表时间:
    2022-07-01
  • 期刊:
  • 影响因子:
    2.1
  • 作者:
    Goupell, Matthew J.;Noble, Jack H.;Phatak, Sandeep A.;Kolberg, Elizabeth;Cleary, Miranda;Stakhovskaya, Olga A.;Jensen, Kenneth K.;Hoa, Michael;Kim, Hung Jeffrey;Bernstein, Joshua G. W.
  • 通讯作者:
    Bernstein, Joshua G. W.
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Joshua Gary Bernstein其他文献

Joshua Gary Bernstein的其他文献

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{{ truncateString('Joshua Gary Bernstein', 18)}}的其他基金

Optimizing bilateral and single-sided-deafness cochlear implants for functioning in complex auditory environments
优化双侧和单侧耳聋人工耳蜗植入物以在复杂的听觉环境中发挥作用
  • 批准号:
    10654316
  • 财政年份:
    2023
  • 资助金额:
    $ 36.75万
  • 项目类别:
Optimizing Bilateral and Single-Sided Deafness Cochlear Implants for Functioning in Complex Auditory Environments
优化双侧和单侧耳聋人工耳蜗植入物以在复杂的听觉环境中发挥作用
  • 批准号:
    9216078
  • 财政年份:
    2016
  • 资助金额:
    $ 36.75万
  • 项目类别:
Modeling speech intelligibility in competing backgrounds by the hearing-impaired
对听障者在竞争背景下的语音清晰度进行建模
  • 批准号:
    8230749
  • 财政年份:
    2010
  • 资助金额:
    $ 36.75万
  • 项目类别:
Modeling speech intelligibility in competing backgrounds by the hearing-impaired
对听障者在竞争背景下的语音清晰度进行建模
  • 批准号:
    7884046
  • 财政年份:
    2010
  • 资助金额:
    $ 36.75万
  • 项目类别:
Modeling speech intelligibility in competing backgrounds by the hearing-impaired
对听障者在竞争背景下的语音清晰度进行建模
  • 批准号:
    8040914
  • 财政年份:
    2010
  • 资助金额:
    $ 36.75万
  • 项目类别:

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