A randomized clinical trial: Examining a brief parent-intervention to reduce college student drinking and cannabis use

一项随机临床试验：检查简短的家长干预以减少大学生饮酒和吸食大麻

• 批准号: 10705167
• 负责人: Robert J Turrisi
• 金额: $ 59.46万
• 依托单位: PENNSYLVANIA STATE UNIVERSITY, THE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-15 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10705167
• 关键词: Acute; Address; Administrator; Air; Alcohol consumption; Alcohols; Anxiety; Attention; Behavior; Binding; Brain; Cannabis; Cardiovascular system; Cellular Phone; Cessation of life; Chronic; Cognition; Cognitive deficits; Communication; Communities; Computers; Control Groups; Data; Decision Making; Development; Evaluation; Family; Feedback; Health; Health Surveys; Heavy Drinking; Home; Individual; Injury; Intervention; Intervention Studies; Legal; Letters; Literature; Mediation; Mediator; Mental Depression; Mental Health; Methods; Military Personnel; Modeling; National Institute on Alcohol Abuse and Alcoholism; Parents; Perception; Performance; Population; Prevention; Prevention strategy; Preventive; Process; Psychoses; Public Health; Publishing; Readability; Reporting; Research; Resources; Review Literature; Risk; Sleep Disorders; Students; Subgroup; Surgeon; Surveys; Tablets; Teenagers; Testing; Universities; age group; alcohol consequences; alcohol measurement; assault; binge drinking; college; college drinking; cost; design; drinking; efficacy evaluation; endogenous cannabinoid system; evidence base; follow-up; high risk; high risk drinking; high school; interest; laptop; marijuana legalization; marijuana use; marijuana user; member; novel; parental influence; physical conditioning; post intervention; primary outcome; psychosocial; randomized, clinical trials; reduced alcohol use; respiratory; secondary outcome; sex; skills; trend; underage drinking; university student

Abstract College students’ risky drinking and cannabis use are major public health problems. Almost 80% of college students report consuming alcohol in the past year and more than 1 in 3 report heavy episodic drinking in the past month. Reports also show that college is a high-risk window for cannabis use. This is highly concerning considering that the potency of present-day cannabis has markedly increased, cannabis use and consequences have also risen, and availability continues to grow due to increased legalization across the U.S. Further, a number of studies have shown an increase in co-use of alcohol and cannabis (use of both substances in the same day), which results in significantly more problems compared to either alcohol-only or cannabis-only use. Our brief parent-based intervention for college students has shown efficacy in reducing risky drinking, but it does not currently have content to address cannabis use or co-use of alcohol and cannabis. Our review of the literature and research in progress reveals there are no studies examining the efficacy of parent interventions to reduce cannabis use in this age group. The proposed research will address this omission, curb the problematic trends noted above, and move the field forward by testing a modified version of our parent-intervention that includes content for parents to have broader discussions about alcohol and cannabis use (referred to as e-PBI+). To assess interest in the college-level cannabis parent-intervention materials, we conducted a pilot survey of 40 college health administrators and all 40 indicated that they have a need for and would implement a parent-intervention that included content on cannabis (see letters of support). We then conducted a pilot RCT study on the e-PBI+ (versus a control condition) and observed preliminary evidence that parents found the e-PBI+’s additional cannabis content interesting and useful, conversations with their students were well received, and more importantly, students were less likely to engage in cannabis use post-intervention. Taken together, these data provide support for further examination of the e-PBI+. Our proposed study will use a rigorous RCT design to examine: 1) The efficacy of the e-PBI+ at 3, 6, 9, and 12 months post-baseline relative to an active comparison condition (our evidence-based parent intervention, the e-PBI), and an attention-matched-control condition (e-AC), on reducing alcohol and cannabis use and consequences (efficacy; Aim 1); 2) Examine the process by which the e-PBI+ influences parents’ and college students’ behaviors (mediation; Aim 2); and 3) Examine subgroups for whom the e-PBI+ is more versus less effective (moderation; Aim 3). To the extent that the research is successful, it will provide an easy to implement and low-cost parent-intervention that provides new cannabis content for parents to have discussions with their college-bound teens about alcohol and cannabis.

抽象的 大学生的风险饮酒和大麻使用是主要的公共卫生问题。几乎80％的大学 学生报告在过去的一年中饮酒，三分之一以上报告了大量的情节性饮酒 过去一个月。报告还表明，大学是大麻使用的高风险窗口。这是非常关注的 考虑到当今大麻的效力已明显增加，大麻使用和 后果也在上升，由于美国合法化的增加，可用性继续增长 此外，许多研究表明，酒精和大麻的共同利用有所增加（两者都使用 同一天的物质），与仅酒精或 仅使用大麻。我们对大学生的简短干预表现出在降低的效率 有风险的饮酒，但目前尚不满足于解决大麻使用或共同使用酒精和 大麻。我们对正在进行的文献和研究的回顾表明，没有研究研究 父母干预措施减少该年龄段的大麻使用的功效。拟议的研究将解决 这种遗漏，遏制上述问题的问题趋势，并通过测试修改后的 我们的父母干预的版本，其中包括父母对酒精进行更广泛讨论的内容 和大麻使用（称为E-PBI+）。评估对大学水平的大麻父母干预的兴趣 材料，我们对40名大学卫生管理员进行了试点调查，所有40位表明他们有一个 需要并将实施父母干预，其中包括大麻上的内容（请参阅支持信）。 然后，我们对E-PBI+（相对于对照条件）进行了一项试验RCT研究，并观察到了初步 证据表明，父母发现E-PBI+的其他大麻含量有趣而有用 他们的学生受到了好评，更重要的是，从事大麻使用的可能性较小 干预后。综上所述，这些数据为进一步检查E-PBI+提供了支持。我们的 拟议的研究将使用严格的RCT设计来检查：1）在3、6、9和12时E-PBI+的效率 基线后相对于主动比较条件（我们的循证父母干预， E-PBI）以及匹配匹配的控制条件（E-AC），用于减少酒精和大麻的使用和 后果（功效；目标1）； 2）检查E-PBI+影响父母和大学的过程 学生的行为（调解；目标2）； 3）检查E-PBI+的亚组比 有效（适度；目标3）。在研究成功的范围内，它将提供易于实施的 和低成本的父母干预，为父母提供新的大麻内容，以便与他们的讨论 关于酒精和大麻的大学青少年。