Core A: Administrative Core

核心A：行政核心

基本信息

批准号：
10731277
负责人：
Kristina De Paris
金额：
$ 14.96万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-06-01 至 2028-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10731277
关键词：
Accounting Administrative Personnel Agreement Automobile Driving B-Lymphocytes Biometry Collaborations Communication Communities Computer Analysis Country Data Data Reporting Databases Decision Making Dedications Doctor of Philosophy Documentation Early identification Ensure Fostering Funding Goals Grant Guidelines HIV HIV vaccine Human Resources Individual Infant Infrastructure Institution International Leadership Macaca mulatta Monitor Occupational activity of managing finances Output Paris, France Physicians Policies Principal Investigator Productivity Regulation Reporting Research Research Activity Research Personnel Research Project Grants Resource Allocation Resource Sharing Resources Schedule Scientist Secure Site Strategic Planning United States National Institutes of Health Universities Vaccination Vaccine Design data management data sharing knowledge integration meetings multidisciplinary neutralizing antibody nonhuman primate operation programs success symposium synergism

Accounting Administrative Personnel Agreement Automobile Driving B-Lymphocytes Biometry Collaborations Communication Communities Computer Analysis Country Data Data Reporting Databases Decision Making Dedications Doctor of Philosophy Documentation Early identification Ensure Fostering Funding Goals Grant Guidelines HIV HIV vaccine Human Resources Individual Infant Infrastructure Institution International Leadership Macaca mulatta Monitor Occupational activity of managing finances Output Paris, France Physicians Policies Principal Investigator Productivity Regulation Reporting Research Research Activity Research Personnel Research Project Grants Resource Allocation Resource Sharing Resources Schedule Scientist Secure Site Strategic Planning United States National Institutes of Health Universities Vaccination Vaccine Design data management data sharing knowledge integration meetings multidisciplinary neutralizing antibody nonhuman primate operation programs success symposium synergism

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项目摘要

ABSTRACT - Administrative Core The Administrative Core (Admin Core) will serve to coordinate, direct, and integrate the Program’s operations, facilitate synergy, and provide the infrastructure and oversight required to achieve the Program’s key scientific goal of identifying the determinants of HIV broadly neutralizing antibody precursors in infant rhesus macaques. The successful implementation and completion of this Program and its scientific goals will require a highly efficient and responsive Admin Core. The Admin Core will be essential for the success of the Program because it will provide 1) management of scientific projects and goals through coordination, relevant resources allocation, and efficient data sharing and reporting; 2) coordination of financial management through close communication and oversight; and 3) documentation of compliance, and thereby reduce the administrative burden of the individual Program components, while guaranteeing efficiency and synergy across all Projects and Cores. In addition, the Admin Core, with the guidance of the External Advisory Board (EAB) and NIH Program, will provide scientific and managerial oversight over the Program’s activities to ensure that steady progress is made towards scientific milestones. Specifically, Aim 1 of the Admin Core will provide overall coordination, communications and data management with dedicated personnel to ensure seamless collaboration and scientific progress and integrity. Aim 2 will ensure timely financial accounting and regulatory oversight to ensure compliance with institutional, federal, and international guidelines. By successfully completing its Aims, this Admin Core will ensure a unified research effort and support for the Program’s overall goal to identify the early determinants of broadly neutralizing antibody precursor induction in infant rhesus macaques. The Admin Core will guarantee efficient and coordinated conduct of all research activities and ensure high relevance of research goals as the field evolves to achieve the Program goal of optimizing HIV vaccine design for the induction of broadly neutralizing antibodies.

摘要 - 行政核心行政核心（管理员核心）将有助于协调，指导和整合程序的操作，促进协同作用，并提供实现该计划的主要科学所需的基础架构和监督鉴定艾滋病毒的决定剂在婴儿恒河猕猴中广泛中和抗体前体的目标。该计划的成功实施和完成，其科学目标将需要高度高效且响应迅速的管理员核心。管理员核心对于该程序的成功至关重要，因为它将通过协调，相关资源分配，提供科学项目和目标的管理，以及有效的数据共享和报告； 2）通过密切沟通协调财务管理和监督； 3）合规文件，从而减少了行政管理单个程序组件，同时保证所有项目和核心的效率和协同作用。此外，在外部咨询委员会（EAB）和NIH计划的指导下，管理员核心将对该计划的活动提供科学和管理的监督，以确保取得稳定的进步走向科学里程碑。具体而言，管理员核心的目标1将提供总体协调，与专用人员的通信和数据管理，以确保无缝协作和科学进步与完整性。 AIM 2将确保及时财务会计和监管监督以确保遵守机构，联邦和国际准则。通过成功完成其目标，该管理员核心将确保统一的研究工作和支持程序的总体目标是确定及早确定广泛中和抗体前体诱导的确定婴儿恒河猕猴。管理员核心将保证所有研究的有效和协调的行为活动并确保随着领域的发展，研究目标的高度相关性，以实现计划目标优化HIV疫苗设计，以诱导广泛中和抗体。