BUILDING INTERDISCIPLINARY RESEARCH CAREERS IN WOMEN'S HEALTH IN KENTUCKY

在肯塔基州建立女性健康跨学科研究事业

基本信息

批准号：
7677878
负责人：
Thomas E Curry
金额：
$ 50万
依托单位：
UNIVERSITY OF KENTUCKY
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
起止时间：
2000-09-30 至 2013-08-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): The primary goal of the proposed BIRCWH Program is to continue to provide Interdisciplinary Women's Health Research (IWHR) scholars with state-of-the-art multidisciplinary training in women's health research that will ensure that they successfully establish independent research careers in academic medicine. To achieve this goal, we have refined and adapted our already successful organizational structure to provide scholars with in-depth training in 4 focused and interacting areas of women's health: 1) drug abuse and its relationship to sex and gender differences, 2) cancer as it relates to women's health, 3) hormonal regulation across a woman's lifespan, and 4) oral health and its impact on cardiovascular and endocrine health and pregnancy outcomes. The 4 current focus areas were chosen as an extension of our previous research areas because research in these areas is of fundamental importance to improving the health of women. Also these 4 focus areas address the 4 overarching themes identified by NIH and ORWH as important for this proposal (interdisciplinary research, sex/gender determinants, lifespan, and health disparities/differences and diversity). We will establish an innovative Shared Resource Laboratory, called Advancing Research Through Support (ARTS), that will provide Scholars with skilled technical services that are unavailable elsewhere in the UK research environment. Finally, we will establish an innovative program whereby former BIRCWH Scholars ("graduates") will act as Coaches by serving as members of research teams and providing an extensive and interactive support network for the IWRH Scholars. A unique feature and an important strength of our BIRCWH Program is its multidisciplinary, cross departmental and interactive nature. This multidisciplinary structure allows us to address a broad range of issues related to public health including addictive behaviors, aging, cancer, diabetes, hormone action, obesity, oral health, and pregnancy. During the previous funding period, we used this interactive structure with considerable success. Therefore, we propose to expand the opportunities afforded to each IWHR Scholar for rich, concentrated, and multidisciplinary experiences with a primary mentor, a former BIRCWH Scholar (Coach), and many other faculty members that will enrich the IWHR Scholar's research experience and provide multiple role models to enhance the Scholar's career development.

描述（由申请人提供）：拟议的BIRCWH计划的主要目标是继续为妇女健康研究的最先进的多学科培训提供跨学科的妇女健康研究（IWHR）学者，以确保他们成功地在学术医学领域建立独立的研究职业。 To achieve this goal, we have refined and adapted our already successful organizational structure to provide scholars with in-depth training in 4 focused and interacting areas of women's health: 1) drug abuse and its relationship to sex and gender differences, 2) cancer as it relates to women's health, 3) hormonal regulation across a woman's lifespan, and 4) oral health and its impact on cardiovascular and endocrine health and pregnancy outcomes.当前的4个重点领域被选为我们以前的研究领域的扩展，因为这些领域的研究对于改善妇女的健康至关重要。同样，这四个重点领域介绍了NIH和ORWH确定的四个总体主题，这对于该提案（跨学科研究，性别/性别决定因素，寿命以及健康差异/差异和多样性）。我们将建立一个创新的共享资源实验室，称为通过支持（ARTS）进行进步研究，该实验室将为学者提供熟练的技术服务，而在英国研究环境中其他地方则无法提供。最后，我们将建立一个创新的计划，以此，前BIRCWH学者（“毕业生”）将通过担任研究团队的成员并为IWRH学者提供广泛而互动的支持网络。 Bircwh计划的独特功能和重要优势是其多学科，跨部门和互动性质。这种多学科结构使我们能够解决与公共卫生有关的广泛问题，包括成瘾行为，衰老，癌症，糖尿病，激素作用，肥胖，口腔健康和怀孕。在上一个资金期间，我们将这种交互结构取得了巨大成功。因此，我们建议将提供富裕，集中和多学科的每个IWHR学者提供的机会与主要导师，前BIRCWH学者（教练）以及许多其他教职员工，以及许多将丰富IWHR学者的研究经验并提供多个榜样，以增强学者的职业发展。

项目成果

期刊论文数量（44）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Physical and mental health status and health behaviors of childhood cancer survivors: findings from the 2009 BRFSS survey.

DOI：
10.1002/pbc.23359
发表时间：
2012-06
期刊：
PEDIATRIC BLOOD & CANCER
影响因子：
3.2
作者：
Phillips-Salimi, Celeste R.;Lommel, Karen;Andrykowski, Michael A.
通讯作者：
Andrykowski, Michael A.

PGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling, P450 activation and drug binding.

PGRMC1（黄体酮受体膜成分 1）：一种靶向蛋白，在类固醇信号传导、P450 激活和药物结合方面具有多种功能。

DOI：
10.1016/j.pharmthera.2008.09.006
发表时间：
2009-01
期刊：
Pharmacology & therapeutics
影响因子：
13.5
作者：
Rohe HJ;Ahmed IS;Twist KE;Craven RJ
通讯作者：
Craven RJ

Influence of estradiol on functional brain organization for working memory.

DOI：
10.1016/j.neuroimage.2011.09.067
发表时间：
2012-02-01
期刊：
NEUROIMAGE
影响因子：
5.7
作者：
Joseph, Jane E.;Swearingen, Joshua E.;Corbly, Christine R.;Curry, Thomas E., Jr.;Kelly, Thomas H.
通讯作者：
Kelly, Thomas H.

Cyclic regulation of apoptotic gene expression in the mouse oviduct.

小鼠输卵管中凋亡基因表达的循环调节。