Puerto Rico Antibiotic Resistance Surveillance in Retail Food (PR-ARS)

波多黎各零售食品抗生素耐药性监测 (PR-ARS)

• 批准号: 10693887
• 负责人: Yadira Malavez
• 金额: $ 18.2万
• 依托单位: UNIVERSITY OF PUERTO RICO AT AGUADILLA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10693887
• 关键词: Puerto; Rico; Antibiotic; Resistance; Surveillance

Antibiotic resistance, a threat to public health worldwide, is exacerbated by misuse and overuse of antibiotics for therapeutic purposes in human and veterinary medicine. National Antimicrobial Resistance Monitoring System (NARMS) is a multi-agency federal program that collaborates with public health and academic institutions in efforts to monitor antimicrobial resistance in bacteria from humans, retail meats, and food-producing animals. Our aim is to collaborate with the Food and Drug Administration to establish a NARMS site in Puerto Rico. The Puerto Rico Antibiotic Resistance Surveillance in Retail Food (PR-ARS) Program’s primary goal is to enhance, strengthen and sustain antibiotic resistance surveillance in retail food specimens as part of NARMS. The strategies of this project address four (4) specific aims: (i) Develop and implement a surveillance system to enhance, strengthen and sustain NARMS; (ii) Develop a trainee program; (iii) Develop a collaboration with the Puerto Rico Department of Health to build capacity for microbial resistance detection and improvement in outreach response; (iv) Develop an outreach program before the end of the third quarter of PY-1 aimed at providing support to public health organizations and empowering communities on antibiotic resistance and its impact on food supply. Through this project, we will establish a collaboration with the Pennsylvania Department of Health and the Pennsylvania State University, which will serve as models and provide training for the success of the PR-ARS. Analyses of integrated genomics data from food and human sources will also enhance surveillance for antimicrobial resistance in enteric bacteria. PR-ARS will generate baseline data about the antimicrobial resistance status of enteric pathogens isolated from retail meats of PR and will provide critical data to FDA for regulatory oversight, which is essential for policy-making and improvements in food safety.

抗生素抵抗是对全球公共卫生的威胁，滥用和过度使用会加剧 用于人类和兽医治疗目的的抗生素。国家抗微生物 阻力监控系统（NARMS）是一个多机构联邦计划，与 公共卫生和学术机构努力监测细菌的抗菌素耐药性 来自人类，零售肉和产生食物的动物。我们的目标是与食物合作 和药物管理局在波多黎各建立了NARMS地点。波多黎各抗生素 零售食品（PR-ARS）计划的主要目标是增强，增强， 加强零售食品标本中的抗生素耐药性监测作为一部分 纳姆斯。该项目的策略针对四（4）个具体目的：（i）开发和实施 一种监视系统，以增强，更强和维持NARMS； （ii）制定学员计划； （iii）与波多黎各卫生部建立合作，以建立能力 微生物抗性检测和外展反应的改善； （iv）发展宣传 PY-1第三季度结束之前的计划旨在为公共卫生提供支持 组织并赋予社区对抗生素耐药性及其对粮食供应的影响。 通过这个项目，我们将与宾夕法尼亚州卫生部建立合作 以及宾夕法尼亚州立大学，该大学将作为模型，并为 公关的成功。对来自食品和人类来源的综合基因组数据的分析将 还提高了肠细菌中抗菌素耐药性的监测。公关将产生 关于从零售中分离的肠道病原体的抗菌耐药性状态的基线数据 PR的肉，将向FDA提供关键数据以进行监管监督，这对于 政策制定和食品安全的改进。