The Mexican Health Aging Study (MHAS)

墨西哥健康老龄化研究 (MHAS)

• 批准号: 10656994
• 负责人: Rebeca Wong
• 金额: $ 149.85万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2028-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10656994
• 关键词: Address; Adult; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Ancillary Study; Blood; COVID-19; COVID-19 pandemic; COVID-19 pandemic effects; Cognitive; Cognitive aging; Cohort Analysis; Collaborations; Communities; Country; DNA Methylation; Data; Data Collection; Databases; Developing Countries; Dimensions; Discrimination; Documentation; Economics; Elderly; Environmental Risk Factor; Epigenetic Process; Equity; Family; Fostering; Funding; Genetic; Geography; Geriatrics; Goals; Health; Health Technology; Health and Retirement Study; Health behavior; Healthcare; Income; Individual; Inequity; Institution; Interdisciplinary Study; Knowledge; Language; Latin America; Lead; Length; Life Cycle Stages; Link; Longitudinal Studies; Mental Health; Mexican; Mexico; Participant; Peer Review; Physical Function; Population; Positioning Attribute; Protocols documentation; Research; Research Personnel; Research Support; Retirement; Running; Rural; Saliva; Sampling; Social Protection; Structure; Surveys; United States; United States National Institutes of Health; Venous; Work; aged; bilingualism; cognitive function; data enclave; design; empowerment; experience; family support; follow-up; health care availability; human old age (65+); improved; instrument; migration; mobile computing; mortality; outreach; perceived discrimination; physical conditioning; population based; preservation; programs; response; rural area; saliva sample; social; statistics; trend; usability; user-friendly; virtual; web platform; web site

The Mexican Health and Aging Study (MHAS) is a longitudinal study using a national sample of community-dwelling adults aged 50 and older in urban and rural Mexico. Six waves of data collection over 20 years have been completed. Since its inception, the protocols and survey instruments are highly comparable to the U.S. Health and Retirement Study (HRS), A key ancillary study of the MHAS is the Mex-Cog, part of the Harmonized Cognitive Aging Protocol (HCAP), conducted in several countries to study Alzheimer's disease and related dementias (ADRD) around the globe using population-based surveys like the MHAS. Two waves of the Mex-Cog have been completed. The long-term goal is to create new knowledge on aging and ADRD for Mexican older adults using a population-based life course perspective. The MHAS is uniquely positioned to sustain research on emerging themes such as COVID-19 and the related social inequities it revealed, providing a strong rationale for adding follow-ups of the MHAS and Mex-Cog, and incorporating new themes to address these knowledge gaps, The specific aims are to: 1) Support further research on the dynamics of aging in Mexico, by extending and improving an existing national panel study, the MHAS. 2) Support further research on the dynamics of Alzheimer's disease and related dementias around the globe, by extending an existing panel of Mex-Cog, an ancillary study of the MHAS; and 3) Foster research on the dynamics of Mexican aging by expanding the knowledge about and promoting the use of the databases and its related products. We will carry out waves 7 and 8 of the MHAS and Wave 3 of the Mex-Cog, We will add a rural over-sample, and incorporate new themes: COVID-19, discrimination, use of languages, and use of technology for health care. We will collect saliva samples in Mex-Cog 3 to support research on genetics of Alzheimer's disease. We will continue the user-friendly web-based platforms and launch a new virtual data enclave to enhance global public access to the data and project documentation. The analytical significance of the new MHAS data will be exceptional, producing a national longitudinal study of aging that spans over twenty-six years, which is unique for a low or middle-income country, The data platform will enhance research on aging in general and ADRD more specifically, and related changes of physical and mental health; physical and cognitive functionality; COVID-19 and other environmental risks; health behaviors and health care use; family support; aging and the life course; wealth, income, labor and retirement; Mexico-U.S. migration; and mortality in a country aging fast with limited institutional support for individuals in old age, and with close social and economic ties to the United States. The data will enable cross-period and cross-cohort analyses, as well as short- and long-run effects on health and aging, and will continue to be highly comparable with similar studies in other countries.

墨西哥卫生和老化研究（MHAS）是一项纵向研究，使用了国家居住的国家样本 墨西哥城市和农村地区50岁及50岁的成年人。 20年来的六波数据收集浪潮 已完成。自成立以来，协议和调查工具与美国高度可比 健康与退休研究（HRS），MHA的主要辅助研究是MEX-COG，是其中一部分 在几个国家进行的研究阿尔茨海默氏病的协调认知老化方案（HCAP） 以及全球相关的痴呆症（ADRD），使用MHA等基于人群的调查。两波 Mex-cog已经完成。 长期目标是使用A 基于人群的生活课程的观点。 MHA的独特位置可以维持有关新兴的研究 诸如Covid-19之类的主题及其揭示的相关社会不平等，为添加的强烈理由提供了 MHA和MEX-COG的后续措施，并结合新主题来解决这些知识差距， 具体目的是：1）通过扩展和 改善现有的国家小组研究，即MHA。 2）支持对动态的进一步研究 阿尔茨海默氏病和全球相关痴呆症，通过扩展现有的Mex-Cog面板 MHA的辅助研究； 3）通过扩展墨西哥衰老动态的研究 了解和促进数据库及其相关产品的使用。我们将进行波浪7 以及Mex-cog的MHA和Wave 3中的8个 主题：COVID-19，歧视，使用语言以及对医疗保健技术的使用。我们将收集 MEX-COG 3中的唾液样品支持对阿尔茨海默氏病遗传学的研究。我们将继续 用户友好的基于网络的平台，并启动一个新的虚拟数据飞地，以增强全球公共访问 数据和项目文档。 新的MHA数据的分析意义将是异常的 跨越二十六年的衰老，对于低收入或中等收入国家来说是独一无二的，数据平台 将更具体地增强对衰老的研究，以及身体和相关的变化 心理健康；身体和认知功能； COVID-19和其他环境风险；健康行为 和医疗保健使用；家庭支持；衰老和生活过程；财富，收入，劳动和退休；墨西哥 - 美国。迁移；在一个迅速老化的国家的死亡率，对老年人的机构支持有限， 并与美国紧密的社会和经济联系。数据将启用跨周期和跨科罗特 分析以及对健康和衰老的短期和长期影响，并将继续很高 与其他国家的类似研究可比。