6th ASM Conference on Cell-Cell Communication in Bacteria

第六届 ASM 细菌细胞间通讯会议

• 批准号: 9398494
• 负责人: BETH ANN LAZAZZERA
• 金额: $ 0.5万
• 依托单位: AMERICAN SOCIETY FOR MICROBIOLOGY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-10 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9398494
• 关键词: American; Antibiotic Resistance; Area; Bacteria; Behavior; Biological; Biotechnology; Career Choice; Cell Communication; Cells; Chemistry; Collaborations; Communication; Communication Research; Complex; Computational Biology; Diffuse; Discipline; Disease; Ecology; Educational process of instructing; Evaluation; Event; Evolution; Faculty; Feedback; Financial Support; Fostering; Funding; Future; Goals; Government; Industry; Infection; Lead; Life; Medical; Mentors; Methods; Microbe; Microbiology; Molecular; Molecular Genetics; Monitor; Oral; Organism; Pathogenesis; Perception; Population Density; Postdoctoral Fellow; Process; Request for Applications; Research; Research Personnel; Role; Scientist; Signal Transduction; Societies; Structural Biologist; Structure; Students; Symbiosis; System; Time; Universities; career; career life balance; college; communication behavior; ethnic diversity; graduate student; interest; meetings; member; microbial; microbial community; multidisciplinary; pathogen; public health relevance; quorum sensing; structural biology; success; symposium; synthetic biology

PROJECT SUMARY Bacteria by definition are single-celled organisms, but they, like other forms of life, have evolved surprising complex methods to coordinated behaviors. Research over the past 25 years has revealed that a wide range of bacteria can communicate by diverse mechanisms. In most cases these microbial conversations occur through the exchange of diffusible signals, although there are also clear examples of contact-dependent communication. Many microbes use these signaling mechanisms to monitor and respond to population density, a process often described as quorum sensing. Much of this research has focused on single species communication, but a growing reseach area is the more complex behavior of communication between multiple species of bacteria or bacteria and other eukaryotic organisms. Interbacterial communication is not however restricted to quorum sensing mechanisms and there is mounting evidence that signaling can function in a range of different capacities. This communication has profound impacts on our understanding of how pathogens and commensals often regulate factors critical for interaction with each other and their hosts. This application requests financial support for the sixth American Society for Microbiology-sponsored conference on Cell-cell Communication in Bacteria, to be held from October 16 – 19, 2017, in Athens, GA. There are two main goals of the CCCB conference. The first is to have the meeting serve as a platform to promote and attract young and ethnically diverse investigators involved in bacterial communication research. Young and diverse researchers will be chosen to be speakers at this conference, and a mentoring lunch will provide students with the opportunity to explore the diversity of career options in the bacterial communication field. The second goal of this conference is to foster interactions between reseachers with diverse expertise. Thus, small groups of researchers will be created that are seated together during lunch, with each member of the group coming from from a different research area: structural biology, computational biology, synthetic biology, chemistry, bacterial molecular genetics, microbial ecology, and microbial pathogenesis. In these small groups scientists will discuss their most pressing research challenges in bacterial communication with the goal of creating new solutions, research ideas, and even future collaborations.

项目概要 根据定义，细菌是单细胞生物，但它们与其他生命形式一样，都是进化而来的 过去 25 年的研究发现了令人惊讶的复杂行为协调方法。 研究表明，在大多数情况下，多种细菌可以通过不同的机制进行交流。 这些微生物对话是通过可扩散信号的交换而发生的， 也是依赖接触进行交流的明显例子。 监测和响应人口密度的信号机制，这是一个经常被描述的过程 这项研究的大部分内容都集中在单一物种的交流上，但 不断增长的研究领域是多个物种之间更复杂的交流行为 细菌或细菌与其他真核生物之间的通讯不是。 然而仅限于群体感应机制，并且有越来越多的证据表明 信令可以以多种不同的方式发挥作用，这种通信具有深远的意义。 影响我们对病原体和共生体如何调节关键因素的理解 为了与彼此及其宿主进行交互，该应用程序请求财务支持。 第六届美国微生物学会主办的细胞-细胞会议 细菌交流，将于 2017 年 10 月 16 日至 19 日在佐治亚州雅典举行。 CCCB会议的两个主要目标一是让会议成为一个平台。 促进和吸引参与细菌研究的年轻和不同种族的研究人员 年轻且多元化的研究人员将被选为演讲嘉宾。 会议和指导午餐将为学生提供探索的机会 细菌通讯领域职业选择的多样性第二个目标。 会议的目的是促进具有不同专业知识的研究人员之间的互动，因此规模较小。 将创建研究人员小组，在午餐期间坐在一起，每个成员 该小组来自不同的研究领域：结构生物学、计算 生物学、合成生物学、化学、细菌分子遗传学、微生物生态学等 在这些小组中，科学家们将讨论最紧迫的微生物发病机制。 研究细菌通讯的挑战，目标是创造新的解决方案， 研究想法，甚至未来的合作。