ShEEP Request for a Kubtec XPERT 80 Shielded Cabinet X-ray System

ShEEP 请求 Kubtec XPERT 80 屏蔽柜 X 射线系统

• 批准号: 9796215
• 负责人: Melissa A Kacena
• 金额: --
• 依托单位: RLR VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-01-01 至 2019-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9796215
• 关键词: Anesthesia procedures; Appointment; Area; Biology; Biomedical Research; Bone Resorption; Calibration; Collaborations; Computer software; Contracts; Core Facility; Devices; Diagnostic radiologic examination; Discipline; Disease; Equipment; Financial compensation; Fostering; Funding; Goals; Health; Image; Image Analysis; Implantation procedure; Indiana; Individual; Interdisciplinary Study; Joints; Lasers; Lead; Maintenance; Malignant Neoplasms; Marrow; Measurement; Measures; Medical; Medical center; Modeling; Monitor; Muscle; Neurosciences; Optics; Orthopedics; Pathology; Price; Productivity; Research; Research Personnel; Research Project Grants; Resolution; Roentgen Rays; Science; Scientist; Secure; Services; Sheep; Ships; Software Tools; Source; Specimen; System; Technology; Time; Transportation; Universities; Veterans; Wireless Technology; Work; base; bone; bone healing; career; cost; design; detector; digital; imaging capabilities; innovation; interest; medical schools; mobile computing; neuromusculoskeletal; oncology; programs; relating to nervous system; research and development; skeletal; touchscreen; user-friendly

The purpose of this application is to secure funding to purchase a Kubtec XPERT 80 shielded cabinet X-ray system for use by multiple investigators with different research disciplines including neural, muscle, and bone biology, collectively called neuromusculoskeletal biology, at the Richard L. Roudebush VA Medical Center (RLR VAMC) at Indianapolis. Neuromusculoskeletal disorders are highly VA-related medical problems, and are urgently unmet medical needs. At the RLR VAMC in Indianapolis, strong interactions and collaborations have been established among multiple investigators with expertise in neuromusculoskeletal disorders. With the purchase of the XPERT 80 shielded cabinet X-ray system, which can be used by VA investigators of different disciplines, such collaborations could be further enhanced. The XPERT 80 shielded cabinet X-ray system that we request combines high contrast digital detectors with user-friendly image analysis software tools to provide images which can be measured to precisely obtain information of interest such as bone resorption/degradation at the joint or within the marrow cavity, bone healing, precision of implant placement, etc. In this application, two specific aims are proposed. In Aim 1, we describe the purchase and maintenance plan of the Kubtec XPERT 80 shielded cabinet X-ray system for use by dedicated VA researchers. We have obtained a quotation from KUB Technologies Inc. for the XPERT 80 shielded cabinet X-ray system. We further discuss the management plan of the XPERT 80 shielded cabinet X-ray system. In Aim 2, we discuss the enhancement of the quality of science and promotion of collaboration among dedicated VA researchers. Over the course of the past 8 years, we have established a strong and dynamic Neuromusculoskeletal research program (NMS) in the Research & Development Service. The XPERT 80 shielded cabinet X-ray system represents state-of-the art X- ray and image analysis technology that can be used for a number of neural, muscular, skeletal, and cancer- related projects. As such, potential acquisition of this system would enhance the current imaging capabilities of our core facilities and allow expansion of collaborative VA-related research projects. There is currently no X- ray system with the capabilities of the XPERT 80 shielded cabinet X-ray system at the VA or anywhere on the Indiana University School of Medicine (IUSM) campus. Our overall objective with the acquisition of the XPERT 80 shielded cabinet X-ray system is to create new collaborations at RLR VAMC that lead to innovative solutions for health problems facing our veterans. To reach our goal, we have formed a team of 16 investigators, with appointments as Research Scientists, Research Career Scientists, Senior Research Career Scientist, and even new promising investigators with Without Compensation appointments (WOC). Having this state-of-the-art X-ray system will certainly open up new avenues of research and collaboration at RLR VAMC that would not be possible without it.

此申请的目的是获得资金来购买 Kubtec XPERT 80 屏蔽柜 X 射线 供神经、肌肉和骨骼等不同研究学科的多名研究人员使用的系统 理查德·劳德布什退伍军人医疗中心的生物学，统称为神经肌肉骨骼生物学 （RLR VAMC）在印第安纳波利斯。神经肌肉骨骼疾病是与 VA 高度相关的医疗问题，并且 亟待满足的医疗需求。在印第安纳波利斯的 RLR VAMC，强有力的互动和合作已经 由具有神经肌肉骨骼疾病专业知识的多名研究人员建立。随着 购买XPERT 80屏蔽柜X射线系统，可供不同VA调查员使用 学科方面，这种合作可以进一步加强。 XPERT 80 屏蔽柜 X 射线系统 我们要求将高对比度数字探测器与用户友好的图像分析软件工具结合起来，以提供 可以测量图像以精确获取感兴趣的信息，例如骨吸收/降解 在关节处或骨髓腔内、骨愈合、植入物放置的精确度等。在此应用中， 提出了两个具体目标。在目标 1 中，我们描述了 Kubtec 的购买和维护计划 XPERT 80 屏蔽柜 X 射线系统，供专门的 VA 研究人员使用。我们已获得报价 来自 KUB Technologies Inc. 的 XPERT 80 屏蔽柜 X 射线系统。我们进一步讨论 XPERT 80 屏蔽柜 X 射线系统的管理计划。在目标 2 中，我们讨论了增强 科学质量和促进退伍军人事务部研究人员之间的合作。在整个过程中 在过去的 8 年里，我们在美国建立了强大且充满活力的神经肌肉骨骼研究计划 (NMS) 研究与开发服务。 XPERT 80 屏蔽柜 X 射线系统代表了最先进的 X- 射线和图像分析技术可用于多种神经、肌肉、骨骼和癌症—— 相关项目。因此，对该系统的潜在收购将增强当前的成像能力 我们的核心设施，并允许扩大与 VA 相关的合作研究项目。目前没有X- 具有 XPERT 80 屏蔽柜 X 射线系统功能的 VA 或任何地方的射线系统 印第安纳大学医学院 (IUSM) 校园。我们收购 XPERT 的总体目标 80 屏蔽柜 X 射线系统将在 RLR VAMC 建立新的合作关系，从而带来创新 解决我们退伍军人面临的健康问题。为了实现我们的目标，我们组建了一个由16人组成的团队 研究人员，被任命为研究科学家、研究职业科学家、高级研究职业 科学家，甚至是获得无偿任命（WOC）的新的有前途的研究人员。有了这个 最先进的 X 射线系统必将为 RLR VAMC 开辟新的研究和合作途径 没有它，这是不可能的。