Short Course on Statistical Genetics & Genomics

统计遗传学短期课程

• 批准号: 8669007
• 负责人: Hemant K. Tiwari
• 金额: $ 21.6万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2018-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8669007
• 关键词: Alabama; Books; Characteristics; Clinical; Communities; Complex; Complex Genetic Trait; Computer software; Computers; Data; Data Analyses; Development; Disease; Education; Educational process of instructing; Evaluation; Faculty; Fees; Funding; Genetic; Genomics; Glean; Human; Language; Lead; Learning; Location; Mental disorders; Methods; Modification; National Institute of General Medical Sciences; Participant; Postdoctoral Fellow; Request for Proposals; Research; Research Personnel; Resources; Rotation; Scientist; Selection Criteria; Series; Services; Staging; Statistical Methods; Students; Susceptibility Gene; System; Training; Travel; Universities; Visit; Work; career; disability; education evaluation; experience; genetic analysis; graduate student; lectures; meetings; member; programs; public health relevance; responsible research conduct; trait; web site; Alabama; Books; Characteristics; Clinical; Communities; Complex; Complex Genetic Trait; Computer software; Computers; Data; Data Analyses; Development; Disease; Education; Educational process of instructing; Evaluation; Faculty; Fees; Funding; Genetic; Genomics; Glean; Human; Language; Lead; Learning; Location; Mental disorders; Methods; Modification; National Institute of General Medical Sciences; Participant; Postdoctoral Fellow; Request for Proposals; Research; Research Personnel; Resources; Rotation; Scientist; Selection Criteria; Series; Services; Staging; Statistical Methods; Students; Susceptibility Gene; System; Training; Travel; Universities; Visit; Work; career; disability; education evaluation; experience; genetic analysis; graduate student; lectures; meetings; member; programs; public health relevance; responsible research conduct; trait; web site

DESCRIPTION (provided by applicant): Major efforts are under way to uncover the specific genetic components of many complex human disorders and quantitative traits. These efforts are generating an unprecedented wealth of data that requires sophisticated statistical analysis in order to maximize the information gleaned from each study. Likewise, many advances have been made in statistical methods for the study of complex genetic traits, and new statistical methods continue to be promulgated. To expedite and significantly advance the search for specific genes that predispose to these complex traits, we propose a series of annual hands-on short courses on statistical genetics and statistical genomics which will enable a far greater number of researchers, including clinical researchers, to participate in, contribute to, and lead such research. These short courses will help equip students, post-doctoral fellows, junior investigators and senior investigators new to the field with the statistical genetic approaches necessary to expedite genomic discovery. The courses will be taught by leading experts in statistical genetics/genomics. Each 5-day course will provide substantial "hands-on" computer training that will effectively increase the number and the expertise of investigators who are pursuing genetic and genomic research. We expect approximately 50 students to attend each course, allowing for intensive interaction between students and faculty. Lectures will be supplemented with extensive discussion sessions, handouts, presentation of worked examples, and interactive demonstrations of statistical genetic data analyses. Finally, we will also initiate a new bursary service, providing funding for 10 course participants to travel to visit a course faculty member of their choice to help initiate or finish a particular project. This will provide an unprecedented collaborative opportunity for course participants and faculty.

描述（由申请人提供）：正在揭示许多复杂人类疾病和定量特征的特定遗传成分的重大努力。这些努力正在产生前所未有的数据，需要复杂的统计分析，以最大程度地利用每项研究收集的信息。同样，用于研究复杂遗传特征的统计方法中也取得了许多进步，并继续颁布新的统计方法。为了加快并大大提高人们对这些复杂特征易感的特定基因的搜索，我们提出了一系列关于统计遗传学和统计基因组学的年度动手简短课程，这些课程将使包括临床研究人员（包括临床研究人员）参与，贡献和主持此类研究。这些简短的课程将有助于为学生，初级调查人员和该领域的高级调查员提供装备，并采用加快基因组发现所需的统计遗传方法。这些课程将由统计遗传学/基因组学领先的领先专家教授。每个为期5天的课程将提供大量的“动手”计算机培训，这些计算机培训将有效地增加追求遗传和基因组研究的调查人员的数量和专业知识。我们希望大约有50名学生参加每门课程，从而可以在学生与教职员工之间进行密集的互动。讲座将补充广泛的讨论会议，讲义，工作示例的介绍以及统计遗传数据分析的互动演示。最后，我们还将启动一项新的助学服务，为10名课程参与者提供资金，以访问他们选择的课程教职员工，以帮助启动或完成特定项目。这将为课程参与者和教师提供前所未有的合作机会。