Clinical Studies Research

临床研究

• 批准号: 8377556
• 负责人: Esteban Gonzalez Burchard
• 金额: $ 68.89万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8377556
• 关键词: Antidiabetic Drugs; Back; Clinical Research; Genotype; Lead; Membrane Transport Proteins; Metformin; Pharmacogenetics; Pharmacogenomics; Population Heterogeneity; Research; Research Personnel; cohort; healthy volunteer; member

Clinical Studies Research will maintain SOPHIE, Studies Of Pharmacogenetcs in Ethnically Diverse Populations, a cohort of healthy volunteers who have agreed to be called back for further pharmacogenetic studies. This team will conduct mechanistic genotype driven clinical studies and participate in collaborative studies with PGRN investigators. Members of this team will lead our large clinical study focused on metformin, an anti-diabetic drug that interacts with multiple transporters

临床研究将维持索菲（Sophie），对种族多样性人群中的药物基因研究，这是一群健康的志愿者，他们同意被召回以进行进一步的药物遗传学研究。该团队将进行机械基因型驱动的临床研究，并与PGRN研究人员一起进行合作研究。该团队的成员将领导我们的大型临床研究，该研究集中于二甲双胍，二甲双胍是一种与多个转运蛋白相互作用的抗糖尿病药物