Weight management for improved pregnancy outcomes
体重管理可改善妊娠结局
基本信息
- 批准号:8007523
- 负责人:
- 金额:$ 2.68万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-05-12 至 2013-04-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAdoptionAdverse effectsAgeApplied ResearchBenefits and RisksBirthBirth WeightBirth traumaBody Weight ChangesBody mass indexCaringCesarean sectionDataDeveloped CountriesDevelopmentDiabetes MellitusDietDiscipline of obstetricsEatingEnergy IntakeEpidemicEquilibriumFetal GrowthFetal MacrosomiaFetusFirst Pregnancy TrimesterFutureGestational AgeGestational DiabetesGoalsHealthHigh birth weight infantHypertensionInfantInstitute of Medicine (U.S.)IntakeInterventionLeadLong-Term EffectsLow PrevalenceManaged CareMeasuresMedicalMorbid ObesityMorbidity - disease rateMothersNational Institute of Diabetes and Digestive and Kidney DiseasesNeonatalNewborn InfantNutritionalObesityOutcomeOutcome AssessmentOutcome MeasureOverweightParticipantPatientsPopulationPostoperative ComplicationsPostpartum PeriodPre-EclampsiaPregnancyPregnancy ComplicationsPregnancy OutcomePregnant WomenPrevalencePublic HealthRandomizedRecommendationRecruitment ActivityResearchRiskSafetySpecific qualifier valueSpontaneous abortionTestingTreatment EfficacyUltrasonographyUnderweightUnited StatesVaginal delivery procedureWeightWeight GainWomandesignfollow up assessmentgroup interventionimprovedinfant deathinterestmembermortalityneonatenutritionpreventprimary outcomeprogramspublic health relevancereproductivesatisfactionsecondary outcomestillbirthtreatment as usualvolunteerweight maintenance
项目摘要
DESCRIPTION (provided by applicant): Historically, under nutrition has been a major health concern. Recently however, over nutrition has also become a serious public health problem in the United States and other industrialized countries. With the new obesity epidemic we see increasing morbidity, mortality, and public health burden, particularly among reproductive-aged women. Whereas morbid obesity was once rare among pregnant women, a rapidly increasing proportion of obstetrics patients now have levels of obesity which dramatically increase their risk of serious pregnancy complications. These complications include increased risk of miscarriage, stillbirth, having a fetus that is too large leading to cesarean section or birth injuries for mom and baby from vaginal delivery, and death of the infant in the newborn period. More than 1/3 of women in the U.S. are now starting their pregnancies with a body mass index or 30 or greater, a condition that was unusual to rare 50 years ago. Given the serious consequences of added weight gain during pregnancy for obese women, such as gestational diabetes, pre-eclampsia, or cesarean delivery, the best strategy during their pregnancy may be to maintain a steady weight rather than gaining 15 pounds or more. Unfortunately, there is little research on the efficacy and feasibility of minimizing weight gain during pregnancy. This study is designed to address that problem. Two hundred women with BMIs of 30 or greater at the start of their pregnancy will be recruited for this feasibility test. All participants will be members of a non-profit managed care organization that provides high-quality obstetrics care. Patients who volunteer to participate will be randomly assigned to either a weight maintenance intervention or to usual care. Participants assigned to the intervention will participate in a weight maintenance program designed to help them eat a nutritionally balanced diet and to also control energy intake to minimize weight gain during their pregnancy. Participants (and their babies) in both groups will participate in follow- up assessments at 2 weeks postpartum, 6 months postpartum and one year postpartum. The primary outcome measures will be mothers' weight gain during pregnancy, the amount of weight retained after delivery, and the proportion of large for gestational age infants. Secondary outcomes will include multiple safety measures of the mothers and their babies. In addition to measures of safety, our secondary analyses will address the feasibility and acceptability of a weight management intervention among obese pregnant women.
描述(由申请人提供):从历史上看,在营养下是一个主要的健康问题。但是,最近,在美国和其他工业化国家,过度营养也已成为严重的公共卫生问题。随着新的肥胖流行病,我们看到发病率,死亡率和公共卫生负担的增加,尤其是在生殖时代的妇女中。尽管病态肥胖症曾经在孕妇中很少见,但妇产科迅速增加的妇产科患者现在具有肥胖的水平,可显着增加其严重怀孕并发症的风险。这些并发症包括增加流产的风险,死产,胎儿的胎儿太大,导致剖宫产,或者因阴道分娩而遭受妈妈和婴儿的出生伤害,以及在新生儿时期的婴儿死亡。现在,超过1/3的妇女正在使用体重指数或30或更高的人开始怀孕,这对于50年前的罕见情况是不寻常的。鉴于肥胖女性在怀孕期间增加体重增加的严重后果,例如妊娠糖尿病,前球或剖宫产,怀孕期间最好的策略可能是保持稳定的体重,而不是增加15磅或更多。不幸的是,关于最大程度地减少怀孕期间体重增加的功效和可行性的研究很少。这项研究旨在解决这个问题。在怀孕开始时,将招募200名BMI 30岁以上BMI的妇女进行此可行性测试。所有参与者将是提供高质量妇产科护理的非营利托管护理组织的成员。自愿参加的患者将被随机分配给体重维持干预措施或通常的护理。分配给干预措施的参与者将参加一项旨在帮助他们吃营养平衡饮食的体重维护计划,并控制能量摄入量以最大程度地减少怀孕期间的体重增加。两组的参与者(及其婴儿)将在产后2周,产后6个月和产后一年的时间参加随访评估。主要结果指标将是母亲在怀孕期间的体重增加,分娩后保留的体重量以及妊娠婴儿的大比例。次要结果将包括母亲及其婴儿的多种安全措施。除了安全措施外,我们的次要分析还将解决肥胖孕妇体重管理干预措施的可行性和可接受性。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Victor J Stevens其他文献
Victor J Stevens的其他文献
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{{ truncateString('Victor J Stevens', 18)}}的其他基金
PREPARE: A randomized trial of a pre-pregnancy weight loss intervention
准备:孕前减肥干预的随机试验
- 批准号:
8695004 - 财政年份:2014
- 资助金额:
$ 2.68万 - 项目类别:
Effectiveness Research on Smoking Cessation in Hospitalized Patients - RCU
住院患者戒烟效果研究 - RCU
- 批准号:
8015434 - 财政年份:2010
- 资助金额:
$ 2.68万 - 项目类别:
Effectiveness Research on Smoking Cessation in Hospitalized Patients - RCU
住院患者戒烟效果研究 - RCU
- 批准号:
8508463 - 财政年份:2010
- 资助金额:
$ 2.68万 - 项目类别:
Effectiveness Research on Smoking Cessation in Hospitalized Patients - RCU
住院患者戒烟效果研究 - RCU
- 批准号:
8145210 - 财政年份:2010
- 资助金额:
$ 2.68万 - 项目类别:
Effectiveness Research on Smoking Cessation in Hospitalized Patients - RCU
住院患者戒烟效果研究 - RCU
- 批准号:
8514415 - 财政年份:2010
- 资助金额:
$ 2.68万 - 项目类别:
Effectiveness Research on Smoking Cessation in Hospitalized Patients - RCU
住院患者戒烟效果研究 - RCU
- 批准号:
8290430 - 财政年份:2010
- 资助金额:
$ 2.68万 - 项目类别:
Analysis of five year follow-up data from the Weight Loss Maintenance Trial
减肥维持试验五年随访数据分析
- 批准号:
7937742 - 财政年份:2009
- 资助金额:
$ 2.68万 - 项目类别:
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