Training Program in the Neurobiology of Substance Use and Abuse

药物使用和滥用的神经生物学培训计划

• 批准号: 8290416
• 负责人: CHARLES W BRADBERRY
• 金额: $ 31.1万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8290416
• 关键词: Alcohol or Other Drugs use; Neurobiology; Substance abuse problem; Training Programs

DESCRIPTION (provided by applicant): This application seeks funding to address the opportunity at the University of Pittsburgh for a coherent training program on the neurobiology of substance use and abuse. The program will support three post- doctoral trainees and three pre-doctoral trainees at the dissertation stage. It is structured around five core areas of training faculty expertise: 1) Systems neurobiology of motivated behavior and cognition 2) Adolescent developmental biology and substance use vulnerability 3) Molecular modulation of neurotransmitter release and reuptake 4) Nicotine reinforcement and relapse 5) Stress responsive brain circuits. A didactic course will address these core areas of focus. There will also be a formal seminar series drawing prominent scientists whose work is at the cutting edge of research into these areas of focus. Extensive training in grant writing is formally incorporated through a "mentored and reviewed" grant writing course requirement. Presentation and analysis skills will be developed through an in-house seminar series in which works in progress will be presented by trainees or other individuals within the University of Pittsburgh substance use research community. The training program will enhance critical skills necessary for success as independent investigators, and the sum of its components will create multiple nodes of interaction between researchers, thereby increasing the breadth and quality of training of the supported individuals.

描述（由申请人提供）：本申请寻求资金来解决匹兹堡大学的机会，以进行有关药物使用和滥用神经生物学的连贯培训计划。该计划将在论文阶段支持三名博士后学员和三名博士前学员。它围绕培训教师专业知识的五个核心领域构建：1）动机行为和认知的系统神经生物学2）青少年发育生物学和物质使用脆弱性3）神经递质的分子调节神经递质的释放和重摄取4）尼古丁增强和复发5）抑制响应式脑脑回旋。教学课程将解决这些核心重点领域。还将有一个正式的研讨会系列绘制著名科学家，他们的工作是对这些重点领域的研究的最前沿。通过“指导和审查”赠款写作课程要求正式纳入赠款写作中的广泛培训。演讲和分析技能将通过内部研讨会系列开发，其中正在进行的工作将由学员或匹兹堡大学物质使用研究社区内的其他人提出。该培训计划将提高作为独立研究人员成功所必需的关键技能，其组成部分的总和将在研究人员之间创造多个相互作用的节点，从而提高受支持个人的培训的广度和质量。