2023 Atherosclerosis

2023 动脉粥样硬化

• 批准号: 10675221
• 负责人: Filip K Swirski
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10675221
• 关键词: Academia; Acceleration; Address; Animal Model; Apolipoproteins B; Area; Arterial Fatty Streak; Arterial Intimas; Asia; Atherosclerosis; Australia; Back; Behavior; Blood Vessels; Canada; Cardiovascular Diseases; Cardiovascular system; Cause of Death; Cell Nucleus; Cell physiology; Cells; Cessation of life; Chronic; Collaborations; Communication; Communities; Data; Dedications; Deposition; Developed Countries; Development; Diabetes Mellitus; Disabled Persons; Discipline; Disease; Ensure; Environment; Equilibrium; Europe; European; Fostering; Gender; Genetic; Genetic Screening; Genomics; Goals; Government; Hearing; Hematopoiesis; Hour; Immune; Immune system; Immunologic Factors; Immunologist; Incidence; Individual; Industry; Inflammation; International; Laboratories; Learning; Life Style; Lipids; Lipoproteins; Machine Learning; Mentors; Metabolic; Molecular; Morbidity - disease rate; Myocardial Infarction; Nerve Degeneration; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Pathologic; Pathway interactions; Patients; Play; Postdoctoral Fellow; Prevention; Productivity; Recording of previous events; Reporting; Research; Research Personnel; Risk Factors; Role; Science; Scientist; Shapes; Site; Social Interaction; South America; Spain; Stroke; Structure; Students; System; Systems Biology; Techniques; Time; Touch sensation; Underrepresented Populations; United States; Vascular Diseases; Voice; Woman; Workplace; arterial remodeling; career; cell type; combat; commune; community building; comorbidity; design; disorder risk; diversity and inclusion; ezetimibe; fighting; frontier; high dimensionality; human model; informal atmosphere; inhibitor; innovation; meetings; mortality; new therapeutic target; next generation; novel; posters; prevent; programs; symposium

Abstract The Gordon Research Conference (GRC) on Atherosclerosis has played a central role in this important field for over 40 years. Although the themes evolve every two years, the format and qualities that make this meeting exceptional are maintained: presentations of cutting-edge unpublished data from leading laboratories within the field and in emerging areas, an environment that encourages open scientific exchange among established and early career investigators from academia, industry and government, and an intimate and inclusive format (<200 attendees) that maximizes productive interactions and discussions between scientists. The goal of the Atherosclerosis GRC conference is to provide a comprehensive overview of research at the cutting edge of the field and the developing frontiers, including the latest and emerging paradigms, the most current techniques for studying atherosclerosis in humans and animal models, and the most promising approaches to prevent and treat cardiovascular disease. The theme of the 2023 meeting is `Molecular mechanisms, genomic modifiers and emerging therapies'. We will: 1) Highlight novel techniques being used to investigate atherosclerosis including high dimensional profiling and spatial organization of vascular and immune cells in the vessel wall, as well as systems biology and machine learning approaches that analyze the atherosclerotic plaque as a whole entity, rather than studying individual cell types as has been done in the past; 2) Discuss new molecular pathways regulating vascular and immune cell function, mechanisms of atherosclerosis regression, immunometabolism, clonal hematopoiesis and genetics of atherosclerosis; 3) Focus on complications of atherosclerosis such as diabetes, myocardial infarction, stroke and neurodegeneration, and 4) Create an inclusive meeting culture that fosters interactions between early and established investigators, welcomes The program will also incorporate short talks and posters from submitted abstracts to capture the latest results and provide ample presentation opportunities for trainees and students. For the first time in 17 years, the Atherosclerosis GRC will be returning to a venue in Europe: the Rey Don Jaime Grand Hotel in Castelldefels, Spain. This site is easily accessed from the United States and Europe (20min from a major airport), and has comprehensive conference facilities, accessible to disabled persons, that accommodate the formal and informal meetings, community meals, and social interactions that make the GRC meetings unique. As the atherosclerosis community is an international group, there has always been strong attendance by our European colleagues of the US-based GRC meetings, and we are excited to bring the meeting closer to them this time. In summary, the Atherosclerosis GRC has been thriving for over 40 years through the support of its strong scientific community and its guiding principles of cutting-edge science, open discussion and inclusion. underrepresented scientists and enables their voices to be heard.

抽象的 戈登动脉粥样硬化研究会议 (GRC) 在这一重要领域发挥了核心作用 40多年。尽管主题每两年更新一次，但这次会议的形式和质量 保持特殊性：展示来自领先实验室的尖端未发表数据 领域和新兴领域，鼓励现有和新兴领域之间开放的科学交流的环境 来自学术界、工业界和政府的早期职业调查员，以及亲密和包容的形式（<200 与会者），最大限度地提高科学家之间富有成效的互动和讨论。的目标 动脉粥样硬化 GRC 会议旨在全面概述动脉粥样硬化领域的前沿研究 领域和发展前沿，包括最新和新兴的范式、最新的技术 研究人类和动物模型中的动脉粥样硬化，以及最有希望的预防和治疗方法 治疗心血管疾病。 2023年会议的主题是“分子机制，基因组修饰剂” 和新兴疗法”。我们将： 1) 重点介绍用于研究动脉粥样硬化的新技术 包括血管壁中血管和免疫细胞的高维分析和空间组织，如 以及从整体上分析动脉粥样硬化斑块的系统生物学和机器学习方法 实体，而不是像过去那样研究单个细胞类型； 2）讨论新分子 调节血管和免疫细胞功能的途径、动脉粥样硬化消退的机制、 免疫代谢、克隆造血和动脉粥样硬化遗传学； 3）关注并发症 动脉粥样硬化，如糖尿病、心肌梗塞、中风和神经退行性疾病，以及 4) 创建 包容性的会议文化，促进早期调查员和已建立的调查员之间的互动，欢迎 该计划还将包括简短的演讲 和来自提交摘要的海报，以捕捉最新结果并提供充足的演示机会 对于实习生和学生。 17 年来，动脉粥样硬化 GRC 将首次回到位于 欧洲：西班牙卡斯特尔德费尔斯的 Rey Don Jaime Grand Hotel。该网站可从 United 轻松访问 国家和欧洲（距离主要机场 20 分钟），并拥有全面的会议设施，可方便前往 为残疾人提供正式和非正式会议、社区聚餐和社交活动的场所 使 GRC 会议独一无二的互动。由于动脉粥样硬化界是一个国际团体， 我们的欧洲同事一直大量出席在美国举行的 GRC 会议，并且 我们很高兴这次能够让会议离他们更近一些。综上所述，动脉粥样硬化 GRC 凭借其强大的科学界的支持及其指导原则，40 多年来一直蓬勃发展 尖端科学、开放讨论和包容。 代表性不足的科学家，并让他们的声音被听到。