ACTG A5164(V 20)-ANTIRETROVIRAL THERAPY FOR HIV-INFECTED ADULTS W/ACUTE OIS

ACTG A5164(V 20)-针对感染 HIV 并患有急性 OIS 的成人的抗逆转录病毒治疗

• 批准号: 7719463
• 负责人: THOMAS A CAMPBELL
• 金额: $ 0.9万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719463
• 关键词: AIDS clinical trial group; Acute; Adult; Adverse effects; Bacterial Infections; Blood; Computer Retrieval of Information on Scientific Projects Database; Effectiveness; Funding; Grant; HIV; Institution; Learning; Opportunistic Infections; Patients; Pharmaceutical Preparations; Purpose; Research; Research Personnel; Resources; Respiratory Tract Infections; Safety; Source; United States National Institutes of Health; antiretroviral therapy; fighting; AIDS clinical trial group; Acute; Adult; Adverse effects; Bacterial Infections; Blood; Computer Retrieval of Information on Scientific Projects Database; Effectiveness; Funding; Grant; HIV; Institution; Learning; Opportunistic Infections; Patients; Pharmaceutical Preparations; Purpose; Research; Research Personnel; Resources; Respiratory Tract Infections; Safety; Source; United States National Institutes of Health; antiretroviral therapy; fighting

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of this study to learn whether it is better to start drugs that fight HIV right away, while a patient are being treated for an OI(opportunistic infection) or BI(bacterial infection), or wait until after the OI or BI has been treated. It is not known whether the HIV drugs cause side effects that could worsen the problems for seriously ill people such as those with OI or BI. Another purpose of this study is to compare the safety and effectiveness of the HIV drugs when started during or after an OI or BI. The purpose of the substudy is to compare the levels of some of the HIV drugs in the blood while a patient is receiving treatment for a respiratory infection and after they have stopped treatment for the respiratory infection.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是了解立即开始对抗HIV的药物，而患者正在接受OI（机会性感染）或BI（细菌感染）治疗，或等到OI或BI接受治疗后等待。 尚不清楚艾滋病毒药物是否会导致副作用会使诸如OI或BI之类的人造成严重患者的问题。 这项研究的另一个目的是比较在OI或BI之内或之后开始或之后艾滋病毒药物的安全性和有效性。 该物质的目的是比较血液中某些艾滋病毒药物的水平，而患者正在接受呼吸道感染的治疗，并在停止治疗呼吸道感染后。