Digital Assistant Supported Medication Adherence and Medical Monitoring Syst

数字助理支持药物依从性和医疗监测系统

• 批准号: 7611869
• 负责人: Anthony Alexander Sterns
• 金额: $ 25.78万
• 依托单位: CREATIVE ACTION, LLC
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-02-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7611869
• 关键词: Activities of Daily Living; Acute; Adherence; Adverse effects; Affect; Age; Aging; American; Apple; Arts; Attitude; Award; Awareness; Back; Behavior; Blood Pressure; Caring; Cause of Death; Cellular Phone; Cessation of life; Clinic; Cognition; Cognitive; Communication; Computer software; Computerized Medical Record; Consent; Contracts; Control Groups; Data; Data Collection; Databases; Development; Devices; Disease; Disease Progression; Doctor of Pharmacy; Dose; Educational Materials; Elderly; Electrocardiogram; Ensure; Exercise; Feasibility Studies; Feedback; Funding; Hand; Health; Health Insurance Portability and Accountability Act; Health Personnel; Health Professional; Healthcare; Heart; Home visitation; Hospitals; House Call; Individual; Internet; Intervention; Ischemic Stroke; Learning; Legal patent; Letters; Link; Location; Mails; Manufacturer Name; Marketing; Medical; Medicine; Monitor; Moods; Names; Non-Prescription Drugs; Ohio; Outcome Study; Pamphlets; Patients; Personal Digital Assistant; Persons; Pharmaceutical Preparations; Pharmacy facility; Phase; Physicians; Preparation; Primary Care Physician; Printing; Procedures; Prosthesis; Publishing; Quality of life; Randomized; Reaction Time; Reporting; Research; Research Personnel; Robotics; Rural Hospitals; Secure; Self Management; Small Business Innovation Research Grant; Specialist; Stroke; Stroke prevention; Surveys; System; Tablets; Telephone; Testing; Time; Touch sensation; Training; Transient Ischemic Attack; Treatment Cost; Treatment Protocols; United States; United States National Institutes of Health; Wireless Technology; base; clinical practice; consumer product; cost; data collection methodology; design; diaries; digital; disability; disturbance in affect; dosage; drug testing; experience; glucose monitor; group intervention; improved; innovation; interest; journal article; medication compliance; pill; post stroke; premature; prototype; public health relevance; research and development; software development; stroke education; stroke recovery; success; Activities of Daily Living; Acute; Adherence; Adverse effects; Affect; Age; Aging; American; Apple; Arts; Attitude; Award; Awareness; Back; Behavior; Blood Pressure; Caring; Cause of Death; Cellular Phone; Cessation of life; Clinic; Cognition; Cognitive; Communication; Computer software; Computerized Medical Record; Consent; Contracts; Control Groups; Data; Data Collection; Databases; Development; Devices; Disease; Disease Progression; Doctor of Pharmacy; Dose; Educational Materials; Elderly; Electrocardiogram; Ensure; Exercise; Feasibility Studies; Feedback; Funding; Hand; Health; Health Insurance Portability and Accountability Act; Health Personnel; Health Professional; Healthcare; Heart; Home visitation; Hospitals; House Call; Individual; Internet; Intervention; Ischemic Stroke; Learning; Legal patent; Letters; Link; Location; Mails; Manufacturer Name; Marketing; Medical; Medicine; Monitor; Moods; Names; Non-Prescription Drugs; Ohio; Outcome Study; Pamphlets; Patients; Personal Digital Assistant; Persons; Pharmaceutical Preparations; Pharmacy facility; Phase; Physicians; Preparation; Primary Care Physician; Printing; Procedures; Prosthesis; Publishing; Quality of life; Randomized; Reaction Time; Reporting; Research; Research Personnel; Robotics; Rural Hospitals; Secure; Self Management; Small Business Innovation Research Grant; Specialist; Stroke; Stroke prevention; Surveys; System; Tablets; Telephone; Testing; Time; Touch sensation; Training; Transient Ischemic Attack; Treatment Cost; Treatment Protocols; United States; United States National Institutes of Health; Wireless Technology; base; clinical practice; consumer product; cost; data collection methodology; design; diaries; digital; disability; disturbance in affect; dosage; drug testing; experience; glucose monitor; group intervention; improved; innovation; interest; journal article; medication compliance; pill; post stroke; premature; prototype; public health relevance; research and development; software development; stroke education; stroke recovery; success

DESCRIPTION (provided by applicant): Creative Action LLC, based in Akron, Ohio, plans to bring to market a personal digital assistant-based health data gathering and reporting system. Researchers interested in studying the effects of medications on older adults will be the initial market for our product. We call our medication adherence and data gathering system the iRxReminder" System. The software is specifically designed and will be tested for use by older adults. The software is specifically designed and will be tested for use by older adults. The system brings together state-of- the-art medication reminding and real-time field data collection and reporting software in a completely portable package. With our commercial partners we will integrate the iRxReminder System with existing electronic medical record systems in Phase II. Our hardware includes a desirable personal digital assistant and integrated pill carrier that ensures an individual will carry the system with them. The pillbox case has been awarded a utility patent (US Patent No. 7337899), nine design patents (US Patent No. D501303-D501309, D509055 Pillbox), and one patent pending. Phase I will include development of the software and completion of a feasibility study. Eligible ischemic stroke and transient ischemic attack (TIA) patients undergoing acute treatment at a regional hospital will be approached for consent and then randomized into either the intervention or control group. At the time of randomization, patients in the control group will receive a post-stroke education and medical information diary to assist them in post-discharge self-management. Patients in the intervention group will receive a personal digital assistant with the iRxReminder software preprogrammed with their medication regimen, and a case with the integrated pillbox. Patients will receive training in use of the all the features of the personal digital assistant at a home visit, including practice responding to the iRxReminder medication-taking and survey prompts. The objectives of Phase I are to demonstrate that older adults have an interest in and capacity post-stoke to sufficiently use the features available and to demonstrate successful usage following training, both through a comprehensive mastery test and through 60 days of usage. At the end of 60 days statistical test will be used to determine if older adults utilize the device in improving self-management of care following a stroke through steady use of software that supports 1) medication reminding, 2) medical and attitudinal surveying, and 3) presentation of educational materials related to stroke; compared to a control group using a printed booklet used in a previous post-stroke care study. The feasibility study will provide the field experience necessary to determine recruitment rates, participation rates, and workable field test data collection procedures for a fully powered health outcomes study in Phase II. PUBLIC HEALTH RELEVANCE: Medication-related problems represent a huge cost to the United States economy. Estimates range from $76 billion dollars (Johnson & Bootman, 1995) to $177 billion (Ernst and Grizzle, 2001). Lack of adherence leads to unnecessary disease progression, disease complications, reduced functional abilities, lower quality of life, and even premature death. Our previous lab (Sterns and Mayhorn, 2006) and extended field research (Sterns, 2005) with 44 older adults (M = 72 yrs.) using a Smartphone in combination with an attached pillbox case provided evidence of 1) improving medication adherence; 2) serving as a link between specialists medicating the individual; and 3) providing feedback to healthcare professionals to better direct medication regimens. The proposed research will demonstrate the feasibility of the system for older adults in Phase I, and demonstrate the utility of the information provided for physicians and for older adult patients in Phase II. Over time, we believe the product can evolve to serve as a cognitive prosthesis for older adults that will reduce overall treatment costs and extend independence and enhance successful aging.

描述（由申请人提供）：总部位于俄亥俄州阿克伦市的Creative Action LLC计划将基于数字助理的健康数据收集和报告系统推向市场。有兴趣研究药物对老年人的影响的研究人员将成为我们产品的初始市场。我们称我们的药物依从性和数据收集系统为“系统”。该软件是专门设计的，并将被老年人使用。该软件是专门设计的，将经过专门设计，并将通过老年人进行测试。该系统汇集了与我们的商业派系中的IRX一起，我们将在iir partement中汇集到最先进的现场数据收集和实时数据收集软件。我们的硬件包括一个理想的个人数字助手和集成的药丸，可确保个人携带该系统将在区域医院接受急性治疗的患者中风和短暂性缺血发作（TIA）患者同意，然后随机分为干预组或对照组。在随机分组时，对照组的患者将获得中风后教育和医学信息日记，以帮助他们进行入院后自我管理。干预组中的患者将通过用药物治疗方案进行预编程的Irxreminder软件，并与Integrated Pillbox进行案例。患者将在家庭访问中接受个人数字助理的所有功能的培训，包括练习回应Irxreminder药物治疗和调查提示。第一阶段的目标是证明老年人对斯托克有兴趣和能力，以充分使用可用的功能，并通过全面的精通测试和使用60天的使用，以证明培训后成功使用培训。在60天结束时，将使用统计测试来确定老年人是否利用该设备通过稳定使用软件来改善护理的自我管理，以支持1）提醒药物，2）医疗和态度测量，以及3）呈现与中风有关的教育材料；与对照组相比，使用了先前的触摸后护理研究中使用的印刷小册子。可行性研究将为确定II阶段全力健康结果研究的招聘率，参与率和可行的现场测试数据收集程序所需的现场经验。公共卫生相关性：与药物有关的问题代表了美国经济的巨大成本。估计从760亿美元（Johnson＆Bootman，1995）到1770亿美元（Ernst and Grizzle，2001年）不等。缺乏依从性会导致不必要的疾病进展，疾病并发症，功能降低，生活质量降低甚至过早死亡。我们以前的实验室（Sterns and Mayhorn，2006年）和扩展现场研究（Sterns，2005），使用智能手机与附带的药盒结合使用了44名老年人（M = 72年）（M = 72年）。 2）用作药物药物的专家之间的联系； 3）向医疗保健专业人员提供反馈，以更好地直接药物治疗方案。拟议的研究将证明该系统在第一阶段对老年人的可行性，并证明了为医生提供的信息的实用性以及在II期中为老年人提供的信息。随着时间的流逝，我们认为该产品可以发展为老年人的认知假体，这些假体将降低总体治疗成本并延长独立性并增强成功的衰老。