Methadone Maintenance and HIV Prevention: A Window of Opportunity in China

美沙酮维持治疗和艾滋病毒预防：中国的机会之窗

基本信息

批准号：
7621260
负责人：
Li Li
金额：
$ 27.52万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-03-02 至 2012-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7621260
关键词：
AIDS prevention AIDS/HIV problem Address Adherence Age Applaud Attention Attitude Behavior Therapy Behavioral Centers for Disease Control and Prevention (U.S.)China Chinese People Client Clinic Commit Communities Complement component C1s Country Data Drops Drug usage Drug user Effectiveness Employment Epidemic Evaluation Face Family Feedback Gender Gills Government HIV Intervention Knowledge Learning Link Maintenance Manuals Measures Modeling Motivation Outcome Participant Phase Pilot Projects Policy Making Population Procedures Process Professional Education Program Development Program Effectiveness Provider Province Randomized Recording of previous events Recruitment Activity Reporting Research Risk Behaviors Risk Management Series Services Social support Stigmata Testing Theoretical model Training Treatment Protocols Work design encryption experience follow-up group intervention improved innovation methadone maintenance physical conditioning primary outcome programs psychologic psychosocial public health relevance quality assurance secondary outcome service intervention skills social stigma standard care therapy design treatment program

项目摘要

DESCRIPTION (provided by applicant): The implementation of the MMT program in China is one of the most significant measures ever taken by the Chinese government to tackle drug use and HIV prevention challenges, and the effectiveness of these programs has implications for HIV and drug use control. Several pilot studies have identified high client drop-out rate, insufficient training of service providers and limited client service as the main challenges these programs face. We propose to take this window of opportunity to address these challenges by developing and testing an intervention, MMT PLUS, to be added on to the current MMT standard care in China. The proposed MMT PLUS intervention is designed primarily for service providers who work at MMT clinics. The proposed intervention pilot will take 2.5 years and proceed in two phases in Sichuan, China. In Phase 1, we will develop intervention manuals and supporting materials, and finalize assessment measures and implementation procedures. We will also recruit and train staff, establish quality assurance procedures and data encryption and data transfer processes. In Phase 2, we will conduct the pilot intervention across 6 MMT clinics involving 30 service providers and 150 MMT clients, and follow up at 3, 6, and 9-month period. The service provider outcomes are adherence to MMT protocol, reduction in prejudicial attitude toward MMT clients, increase in comfort working with MMT clients, and increase in motivating clients and making personalized risk management plan. The client outcomes are increased motivation to change, improved psychological and physical health, increased positive support network, and reduced HIV risk behavior. PUBLIC HEALTH RELEVANCE: China CDC, the collaborating agency for this study, is the leading force in implementing the current MMT program and has committed to develop new, innovative MMT models for nation-wide dissemination. The findings of this pilot could provide benefits for China and beyond by advancing the field through the sharing of our experience and the lessons learned in integrating a behavioral intervention into a primarily pharmacological model of methadone maintenance, and in transferring timely program development findings to country-wide implementation and policy-making.

描述（由申请人提供）：中国MMT计划的实施是中国政府为应对吸毒和预防艾滋病毒的挑战所采取的最重要的措施之一，这些计划的有效性对艾滋病毒和毒品使用控制具有影响。一些试点研究已经确定了高客户辍学率，服务提供商的培训不足以及客户服务有限，这是这些计划面临的主要挑战。我们建议通过开发和测试干预措施MMT Plus来解决这些挑战，以应对中国当前的MMT标准护理。拟议的MMT Plus干预主要是为在MMT诊所工作的服务提供商设计的。拟议的干预飞行员将需要2。5年的时间，并在中国四川分为两个阶段。在第1阶段，我们将制定干预手册和支持材料，并最终确定评估措施和实施程序。我们还将招募和培训员工，建立质量保证程序以及数据加密和数据传输过程。在第2阶段，我们将在6个MMT诊所进行试点干预，涉及30个服务提供商和150个MMT客户，并在3、6和9个月的时间内进行跟进。服务提供商的成果是遵守MMT协议，对MMT客户的偏见态度的降低，与MMT客户合作的舒适性增加，并增加激励客户并制定个性化的风险管理计划。客户的结果是增加改变，改善心理和身体健康，增加积极支持网络并减少艾滋病毒风险行为的动力。公共卫生相关性：这项研究的合作机构中国CDC是实施当前MMT计划的主要力量，并致力于开发用于全国范围内传播的新的创新MMT模型。这位飞行员的发现可以通过分享我们的经验以及将行为干预措施融入美沙酮维护的药理模型，并将及时的计划开发结果转移到全国范围内的实施和政策制定方面，从而为中国和超越领域提供利益。