The Administrative Core

行政核心

• 批准号: 10629164
• 负责人: DANIEL N STREBLOW
• 金额: $ 13.07万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-15 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10629164
• 关键词: Adjuvant; Binding; Collaborations; Communication; Complex; Contracts; Cytomegalovirus; Decision Making; Doctor of Philosophy; Emerging Communicable Diseases; Ensure; Environment; Fostering; Goals; Grant; Hematopoietic stem cells; Human; Institution; International; Maintenance; Molecular; Monitor; National Institute of Allergy and Infectious Disease; Office of Administrative Management; Pacific Northwest; Pathogenesis; Principal Investigator; Reporting; Research; Resources; Signal Pathway; Signal Transduction; United States National Institutes of Health; Viral; Virus Latency; biodefense; cell growth regulation; collaborative environment; data dissemination; data sharing; experience; meetings; member; programs; reactivation from latency

SUMMARY - ADMINISTRATIVE CORE (CORE C) The overall goal of this PPG is to elucidate the molecular mechanisms of HCMV regulation of cellular signaling in the establishment and maintenance of viral latency and viral reactivation. To meet this goal, we have assembled an extraordinary group of virologists who will collaborate in five highly interactive projects and two scientific cores. The Program Director (PD) and Principal Investigator of the Administrative Core is Jay Nelson, Ph.D., who is a senior molecular virologist with extensive experience studying the molecular interaction of cytomegaloviruses and their host environment. Dr. Nelson will be co-leading this program with Dr. Andrew Yurochko, who is an international expert in the study of Human Cytomegalovirus dissemination and pathogenesis. They will be assisted by an exceptional administrative team that has a proven track record in administering and managing large, complex grants and contracts such as the Pacific Northwest Regional Center of Excellence in Biodefense and Emerging Infectious Diseases (PNWRCE), two NIAID Adjuvant Discovery Contracts, and the ongoing original P01 on which this renewal proposal is built upon. The significant experience of this group with the organization, reporting and communications associated with the successful administration of multi-institutional research programs will be invaluable in ensuring a successful management of this PPG. The Administrative Core will serve as a hub for administration, communication and monitoring for the entire program. The core will serve all projects and all scientific cores, and it will interact with all institutions involved in this program. The Administrative Core will also serve as a central point of interaction with NIH Program. Finally, the administrative team will assist the program director in ensuring regular and timely communication among the members of this consortium as well as reporting to NIAID program.

摘要 - 行政核心（核心 C） 该 PPG 的总体目标是阐明 HCMV 调节细胞信号传导的分子机制 病毒潜伏期和病毒再激活的建立和维持。为了实现这一目标，我们有 组建了一支非凡的病毒学家团队，他们将在五个高度互动的项目和两个项目中进行合作 科学核心。行政核心的项目总监 (PD) 和首席研究员是 Jay Nelson， 博士，资深分子病毒学家，在研究病毒分子相互作用方面拥有丰富经验 巨细胞病毒及其宿主环境。尼尔森博士将与安德鲁博士共同领导该项目 Yurochko，人类巨细胞病毒传播和研究领域的国际专家 发病。他们将得到一支杰出的管理团队的协助，该团队在以下方面拥有良好的记录 管理和管理大型、复杂的赠款和合同，例如太平洋西北地区 生物防御和新发传染病卓越中心 (PNWRCE)，两种 NIAID 佐剂 发现合同，以及正在进行的原始 P01，此更新提案是建立在其基础上的。显着的 该小组在与成功相关的组织、报告和沟通方面的经验 多机构研究计划的管理对于确保成功管理至关重要 此 PPG 的。行政核心将作为管理、沟通和监控的中心 整个计划。核心将服务于所有项目、所有科学核心，并与所有机构互动 参与这个计划。行政核心还将作为与 NIH 互动的中心点 程序。最后，行政团队将协助项目总监确保定期、及时 该联盟成员之间的沟通以及向 NIAID 计划报告。