Global Infectious Diseases and HPV Research Training in Kenya

肯尼亚全球传染病和 HPV 研究培训

基本信息

批准号：
10629160
负责人：
Michael Hoonbae Chung
金额：
$ 24.66万
依托单位：
AGA KHAN UNIVERSITY (KENYA)
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-03 至 2025-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10629160
关键词：
Address Africa Cessation of life Clinical Clinical Research Communicable Diseases Country Detection Discipline of Nursing Educational workshop Extramural Activities Faculty Fellowship Fred Hutchinson Cancer Research Center Goals Grant Health Health Priorities Home Human Papillomavirus Human papilloma virus infection Infection Institution International Joints Journals Kenya Knowledge Leadership Learning Malignant Neoplasms Malignant neoplasm of cervix uteri Manuscripts Medical Medical Faculty Mentors Nursing Faculty Persons Positioning Attribute Prevention Public Health Publishing Recording of previous events Research Research Personnel Research Training Scientist Sexually Transmitted Diseases Short-Term Course Students Tanzania Training Training Programs Uganda Universities Washington Work Writing low and middle-income countries member next generation online course prevent programs skills

项目摘要

ABSTRACT Human papillomavirus (HPV) is the most common sexually transmitted infection in the world with 85% of infections occurring in low and lower middle income countries (LMIC). Nearly all cervical cancer is due to persistent HPV infection with 87% of all cervical cancer deaths occurring in LMIC. Detecting, preventing, and treating HPV infection is thus a major health priority for the country and the region. Aga Khan University East Africa (AKU) is a premier medical and nursing academic institution uniquely situated to address global infectious diseases and HPV. It is a growing university with campuses in Kenya, Uganda, and Tanzania, and it has initiated the first clinical infectious diseases (ID) fellowship for medical doctors in East Africa. However, in order to achieve its goal to become a top research institution, AKU needs further research capacity building and support to train a critical mass of health researchers at AKU with in-depth scientific expertise. The objectives of this proposal are to: 1) increase research into the prevention, detection, and treatment of HPV infection and its impact on cancer; 2) strengthen the capacity of AKU to conduct research in infectious diseases; and 3) expand knowledge and skills in clinical research across AKU campuses in East Africa. The proposed research training program will be led by Drs. Marleen Temmerman and Michael Chung who will be Multiple Program Directors. Together, they will partner AKU with the University of Washington (UW) and its extensive history of successfully implementing research training programs in Kenya. The UW has trained hundreds of Kenyans in health research for over 30 years. UW is also home to a world-renowned HPV Research Group led by faculty experts from the UW and the Fred Hutchinson Cancer Research Center. Drs. Temmerman and Chung will establish a joint research training program for Kenyans with three tracks of varying duration. The long-term track will allow AKU ID fellows to earn a UW Master’s in Public Health (MPH) degree by taking classes in Seattle and conducting fieldwork in Kenya; the medium-term track will invite AKU medical and nursing faculty researchers for 3 months of classes at UW followed by a mentored project in Kenya; and the short-term track will give an opportunity for AKU faculty, staff, and students throughout East Africa to learn grant and manuscript writing and leadership skills through in-person workshops in Nairobi, Kenya and online courses from the UW. A total of 3 AKU ID fellows will earn MPH degrees at the UW, 10 AKU faculty members will undergo non-degree coursework at the UW, and hundreds of trainees will take the workshops and online courses. After graduating, the ID fellows will be offered academic medical positions at AKU and join faculty and staff who have been trained in the medium- and short-term courses at AKU to build sustainable research capacity. By the end of the program, AKU faculty will be able to conduct quality HPV research, publish in internationally-recognized journals, conduct courses to train the next generation of HPV scientists, and independently obtain extramural grants to support their work.

抽象的人乳头瘤病毒 (HPV) 是世界上最常见的性传播感染，占 85% 低收入和中低收入国家（LMIC）发生的感染几乎都是由宫颈癌引起的。持续性 HPV 感染导致中低收入国家 87% 的宫颈癌死亡发生在检测、预防和治疗中。因此，治疗 HPV 感染是该国和该地区阿加汗大学东部的一个主要健康优先事项。非洲 (AKU) 是一流的医疗和护理学术机构，具有独特的优势来解决全球传染病问题这是一所不断发展的大学，在肯尼亚、乌干达和坦桑尼亚设有校区，并已启动。然而，为了实现东非医生的第一个临床传染病（ID）奖学金。 AKU 的目标是成为顶尖研究机构，需要进一步的研究能力建设和培训支持 AKU 拥有大量具有深厚科学专业知识的健康研究人员该提案的目标是。 1) 加强对 HPV 感染的预防、检测和治疗及其影响的研究癌症；2) 加强 AKU 开展传染病研究的能力；3) 扩大东非 AKU 校区临床研究的知识和技能拟议的研究。培训计划将由 Marleen Temmerman 博士和 Michael Chung 博士领导，他们将担任多个项目他们将共同与 AKU 和华盛顿大学 (UW) 及其悠久的历史进行合作。华盛顿大学在肯尼亚成功实施了研究培训项目，已培训了数百名肯尼亚人。威斯康星大学拥有 30 多年的健康研究经验，也是由教师领导的世界著名的 HPV 研究小组的所在地。来自华盛顿大学和 Fred Hutchinson 癌症研究中心的专家和 Chung 博士将出席。为肯尼亚人建立一个为期三个不同期限的联合研究培训计划。轨道将允许 AKU ID 研究员通过参加下列课程获得华盛顿大学公共卫生硕士学位 (MPH) 学位西雅图并在肯尼亚进行实地考察；中期赛道将邀请AKU医疗和护理人员教师研究人员在华盛顿大学进行了 3 个月的课程，随后在肯尼亚和美国进行了一个指导项目；短期课程将为整个东非的 AKU 教职员工和学生提供机会通过肯尼亚内罗毕的现场研讨会学习拨款和手稿写作以及领导技能共有 3 名 AKU ID 研究员将在 UW 获得 MPH 学位，10 名 AKU 教师将获得该学位。成员将在华盛顿大学接受非学位课程，数百名学员将参加研讨会并毕业后，ID 研究员将在 AKU 获得学术医学职位并加入教职。以及在 AKU 接受过中短期课程培训的工作人员，以建立可持续的研究到该计划结束时，AKU 教师将能够进行高质量的 HPV 研究，并在国际认可的期刊，举办培训下一代 HPV 科学家的课程，以及独立获得校外补助金来支持他们的工作。

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

High Acceptability of Assisted Partner Notification Services Among HIV-Positive Females in Kenya: Results From an Ongoing Implementation Study.

肯尼亚艾滋病毒呈阳性女性对辅助伴侣通知服务的高度接受度：一项正在进行的实施研究的结果。

DOI：
发表时间：
2021-01-01
期刊：
影响因子：
0
作者：
Sharma, Monisha;Kariithi, Edward;Kemunto, Emily;Otieno, George;Lagat, Harison;Wamuti, Beatrice;Obongo, Chris;Macharia, Paul;Masyuko, Sarah;Bosire, Rose;Mugambi, Mary;Weiner, Bryan;Farquhar, Carey
通讯作者：
Farquhar, Carey

Implementation fidelity to HIV assisted partner services (aPS) during scale-up in western Kenya: a convergent mixed methods study.

在肯尼亚西部扩大规模期间对艾滋病毒辅助合作伙伴服务 (aPS) 的实施忠诚度：一项聚合混合方法研究。

DOI：
发表时间：
2023-05-19
期刊：
影响因子：
2.8
作者：
Wamuti, Beatrice;Owuor, Mercy;Liu, Wenjia;Katz, David;Lagat, Harison;Otieno, George;Kariithi, Edward;Macharia, Paul;Masyuko, Sarah;Mugambi, Mary;Farquhar, Carey;Weiner, Bryan
通讯作者：
Weiner, Bryan

'My people perish for lack of knowledge': barriers and facilitators to integrated HIV and hypertension screening at the Kenyatta National Hospital, Nairobi, Kenya.

“我的人民因缺乏知识而灭亡”：肯尼亚内罗毕肯雅塔国家医院艾滋病毒和高血压综合筛查的障碍和促进因素。

DOI：
发表时间：
2023-01
期刊：
影响因子：
2.7
作者：
Wamuti, Beatrice;Owuor, Mercy;Magambo, Christine;Ndegwa, Margaret;Sambai, Betsy;Temu, Tecla M;Farquhar, Carey;Bukusi, David
通讯作者：
Bukusi, David

HIV assisted partner services (aPS) to support integrated HIV and hypertension screening in Kenya: a pre-post intervention study.

艾滋病毒辅助合作伙伴服务 (aPS) 支持肯尼亚艾滋病毒和高血压综合筛查：一项干预前研究。

DOI：
发表时间：
2023-12-01
期刊：
影响因子：
4.5
作者：
Wamuti, Beatrice;Sambai, Betsy;Magambo, Christine;Ndegwa, Margaret;Macharia, Paul;M Temu, Tecla;Farquhar, Carey;Bukusi, David
通讯作者：
Bukusi, David

Real-world impact of integrating HIV assisted partner services into 31 facilities in Kenya: a single-arm, hybrid type 2 implementation-effectiveness study.

将艾滋病毒援助合作伙伴服务纳入肯尼亚 31 个设施的现实影响：一项单臂、混合 2 类实施有效性研究。

DOI：
发表时间：
2023-05
期刊：
影响因子：
0
作者：
Sharma, Monisha;Naughton, Brienna;Lagat, Harison;Otieno, George;Katz, David A;Wamuti, Beatrice M;Masyuko, Sarah;Bosire, Rose;Mugambi, Mary;Roy Paladhi, Unmesha;Weiner, Bryan J;Kariithi, Edward;Farquhar, Carey
通讯作者：
Farquhar, Carey