SUBPROJECT: HLA TYPING AND DNA REPOSITORY

子项目：HLA 分型和 DNA 存储库

• 批准号: 7719602
• 负责人: Edwin Allan Smith
• 金额: $ 0.08万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719602
• 关键词: Bos taurus; Cattle; Collagen Type I; Computer Retrieval of Information on Scientific Projects Database; DNA; Disease; Enrollment; Funding; Future; Genetic; Grant; HLA Antigens; Health Sciences; Institution; Molecular Abnormality; Oral; Patients; Phase II Clinical Trials; Purpose; Research; Research Personnel; Resources; Scleroderma; Site; Source; Specimen; Tennessee; United States National Institutes of Health; Universities; leukocyte antigen typing; repository

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to perform HLA(human leukocyte antigen)typing on patients with scleroderma who were enrolled in the recently completed NIH sponsored "Multicenter Phase II Trial of Oral Bovine Type I Collagen in Scleroderma". Since scleroderma is as uncommon disease about which little is known, the purpose is to store DNA from these scleroderma patients for future genetic studies of potential genetic abnormalities in the disease. Specimens will be sent to the University of Tennessee Health Science Center to be kept in a specimen repository. Primary site is UT. MUSC plus several other sites are under subcontract.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是对硬皮病患者进行HLA（人类白细胞抗原），这些患者被招募了最近完成的NIH赞助的“ scleroderma口服I型I型I型胶原蛋白的多中心II期试验”。 由于硬皮病是鲜为人知的疾病，因此目的是存储这些硬皮病患者的DNA，以便对疾病潜在遗传异常的未来遗传研究。 标本将被送到田纳西大学健康科学中心，以保存在标本存储库中。 主要站点是UT。 MUSC加上其他几个地点处于分包合同下。