UPRCCC/MDACC: Partnership for Excellence in Cancer Research

UPRCCC/MDACC：癌症研究卓越合作伙伴关系

• 批准号: 7591293
• 负责人: Jose F Cordero
• 金额: $ 158.49万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-16 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7591293
• 关键词: UPRCCC; MDACC; Partnership; Excellence; Cancer

DESCRIPTION (provided by applicant): This is a resubmission for The University of Puerto Rico Comprehensive Cancer Center (UPRCCC) and The University of Texas M. D. Anderson Cancer Center (MDACC) Partnership for Excellence in Research Grant, which addresses comments and recommendations from the 1) summary statement, 2) NCI Site Visit, and 3) IAC and PSC Committees. Areas strengthened in this application include: leadership, communication, committee oversight, evaluation, career development and mentorship. Funds granted in this award will be used to: 1) support 3 full projects in cancer biology and prevention and 1 pilot project in epidemiology, 2) enhance existing collaborations and establish new collaborations, 3) increase faculty/trainee participation in the training program, 4) expand efforts in our Outreach Program to impact a larger audience, and 5) fortify and stabilize the infrastructure developing at the UPRCCC. Research grants included target 1) developing new cancer imaging techniques, 2) regulating RNA in eukaryotic cells, 3) reducing cancer risk through combined alcohol and tobacco treatment and 4) assessing the role of insulin resistance syndrome as a risk factor for endometrial cancer. The Outreach Program, which was added into the original grant mid-year 3, has been expanded to include cancer related to tobacco, as well as breast, cervical and HPV. The Training Program has also been expanded in scope to impact more faculty and trainees through a comprehensive career development and mentorship training program. The original grant (2002) was awarded to establish a comprehensive long-term mutually beneficial relationship to target and eradicate cancer health disparities. The two short term objectives of the original application were met: 1) develop independent cancer research investigators and 2) establish a strong working relationship based on mutual benefit, identified strengths and reciprocity. The 3rd long-term objective of the Partnership is to regain NCI-designation for the UPRCCC. Thus far, the Partnership has set the foundation for a dynamic collaboration dedicated to enhancing each partner's strengths and eliminating each partner's weaknesses. The Partnership has also served as the catalyst for two major laws passed in Puerto Rico, one of which resulted in the allocation of funding for establishing the infrastructure and recruiting top notch faculty to the UPRCCC. As of 2008, the Partnership is far from reaching its long-range goal of regaining NCI-designation for the UPRCCC. Funding for the U54 resubmission is critical to maintain the momentum of the Partnership's joint efforts in Cancer Research, Training and Outreach.

描述（由申请人提供）：这是对波多黎各大学综合癌症中心（UPRCCC）和德克萨斯大学M. D. Anderson Cancer Center（MDACC）卓越研究赠款的伙伴关系的重新提交，该伙伴关系涉及1个摘要声明的评论和建议），2）NCI站点访问等等，以及3）IAC和3）IAC和PSC和PSC和PSC和PSC和PSC委员会。在此应用程序中加强的领域包括：领导，沟通，委员会监督，评估，职业发展和指导。该奖项中授予的资金将用于：1）支持3个完整的癌症生物学和预防项目的完整项目，以及1个流行病学的试点项目，2）增强现有合作并建立新的合作，3）增加教师/学员参与培训计划，4）扩大我们在我们的外展计划中的努力，以影响更大的受众群体，并在Infrastrasture infrrastruct confrasture confrasture infrastruce confcccccccccccccccccccccccccc.研究补助金包括目标1）开发新的癌症成像技术，2）调节真核细胞中的RNA，3）通过合并的酒精和烟草治疗来降低癌症风险； 4）评估胰岛素抵抗综合征作为子宫内膜癌的危险因素的作用。外展计划被添加到原始赠款3年中，已扩展到包括与烟草以及乳房，宫颈和HPV有关的癌症。该培训计划还扩大了范围，通过全面的职业发展和指导培训计划影响更多的教职员工和受训者。授予了原始赠款（2002年），以建立与目标和消除癌症健康差异的全面长期互惠关系。实现了原始应用的两个短期目标：1）发展独立的癌症研究研究者，2）建立基于相互利益，确定的优势和互惠的牢固的工作关系。该伙伴关系的第三个长期目标是重新获得UPRCCC的NCI设计。到目前为止，伙伴关系为动态合作奠定了基础，致力于增强每个伴侣的优势并消除每个伴侣的弱点。该合作伙伴关系还成为波多黎各通过的两项主要法律的催化剂，其中一项是为建立基础设施和招募顶级教师的资金分配给UPRCCC。截至2008年，该合作伙伴关系远未达到重新获得UPRCCC NCI设计的远程目标。为U54重新提交的资金对于维持伙伴关系在癌症研究，培训和外展方面的共同努力的势头至关重要。