Biostatistics Core

生物统计学核心

• 批准号: 7656683
• 负责人: Robert M. Hamer
• 金额: $ 20.7万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-01 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7656683
• 关键词: Address; Biometry; Biostatistics Core; Collaborations; Consultations; Data; Data Analyses; Data Collection; Doctor of Philosophy; Education; Educational process of instructing; Ensure; Equipment; Goals; Human Resources; Life; Manuscripts; Measurable; Measures; Medical; Methods; Monitor; Paper; Procedures; Production; Quality Control; Reporting; Research; Research Design; Research Methodology; Research Personnel; Research Project Grants; Role; Sample Size; Series; Services; Statistical Data Interpretation; Statistical Methods; Students; System; Testing; Universities; Work; Writing; data management; design; member; programs; quality assurance; tool

The primary objective of the Biostatistics and Data Management Core (BDMC) of the CCNMD is to provide CCNMD investigators with expertise in study design and planning, project implementation and data management, statistical methods and statistical analysis, including interpretation and dissemination of results, and consultation and education. The BDMC draws on the expertise of its two Ph.D. biostatisticians, its data manager, and other biostatisticians elsewhere in the Center, Department, and the University. Study design and planning includes focus of the research questions, production of testable hypotheses involving measurable variables of use in testing the hypotheses, design of the studies, plans for statistical analysis, and power and sample size calculations. Project implementation includes service of the core director on the Steering Committee and Data Management includes forms design, quality control and testing of existing forms, design and testing of the data entry and data management systems, continuing consultation with and meeting with project directors, quality control and quality assurance, and interim administrative reports. It further includes statistical and data consultation if new issues arise during the implementation of the projects. Statistical methods include the detailed design of the statistical analyses of the data in each project, as well as the design of new hypotheses to consider in each project, which depend on results in other projects. Data from each project may suggest hypotheses to test using data from the other projects. It further includes planned statistical analyses of data from all projects, as well as exploratory analyses suggested by the data, which need to be conducted in a rigorous manner, which controls for multiple comparisons. Interpretation and dissemination of results includes working with investigators to ensure that interpretation of results are well supported by the data, authoring or coauthoring the results sections of reports and manuscripts, and working with investigators in writing discussion sections. Consultation and teaching include ongoing consultation with project investigators in order to ensure that data are collected and entered in a timely and accurate manner, and educating investigators, residents, and fellows about statistical methodological issues important to these projects, and to psychiatric and other medical research projects more generally. BDMC personnel will present a series of seminars on research methodology and statistical methods to investigators, residents, fellows, and students.

CCNMD的生物统计学和数据管理核心（BDMC）的主要目标是提供 CCNMD研究人员具有研究设计和计划，项目实施和数据方面的专业知识 管理，统计方法和统计分析，包括解释和传播 结果，咨询和教育。 BDMC借鉴了其两位博士学位的专业知识。生物统计学家， 它的数据经理以及中心，系和大学其他地方的其他生物统计学家。学习 设计和计划包括研究问题的重点，涉及可检验的假设的产生 测试假设，研究设计，统计分析计划的可测量使用变量， 和功率和样本量计算。项目实施包括在 指导委员会和数据管理包括表格设计，质量控制和现有的测试 数据输入和数据管理系统的形式，设计和测试，继续与 与项目主管，质量控制和质量保证以及临时行政报告会面。它 如果在实施项目期间出现了新问题，则还包括统计和数据咨询。 统计方法还包括每个项目中数据统计分析的详细设计 作为在每个项目中要考虑的新假设的设计，这取决于其他项目的结果。数据 每个项目都可以提出假设使用其他项目的数据进行测试。它进一步包括 对所有项目的数据的计划统计分析，以及数据提出的探索性分析， 需要以严格的方式进行，以控制多个比较。解释 结果的传播包括与研究人员合作以确保结果的解释是 在数据和手稿的结果部分以及 与研究人员一起写讨论部分。咨询和教学包括持续的 与项目调查人员进行协商，以确保及时收集和输入数据 准确的方式，并教育研究人员，居民和研究员有关统计方法论问题 对于这些项目，对精神病和其他医学研究项目很重要。 BDMC 人员将提出一系列有关研究方法和统计方法的研讨会 调查人员，居民，研究员和学生。