The InChianti Study

因基安蒂研究

• 批准号: 7732390
• 负责人: Jack M Guralnik
• 金额: $ 35.82万
• 依托单位: NATIONAL INSTITUTE ON AGING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7732390
• 关键词: Age; Aging-Related Process; Anniversary; Biological; Biometry; Clinic; Cohort Studies; Collaborations; Demography; Disease; Elderly; Elements; Enrollment; Epidemiology; Evaluation; Event; Follow-Up Studies; Goals; Health; Home environment; Impairment; Informed Consent; Intervention; Interview; Interviewer; Italy; Laboratories; Lead; Normal Range; Participant; Performance; Persons; Population; Procedures; Proxy; Psyche structure; Range; Registries; Risk Factors; Sampling; Score; Site; Staging; Testing; Time; Walking; Woman; age group; aged; cohort; experience; follow-up; functional loss; men; rural area; urban area

InCHIANTI is being performed in two sites: Greve in Chianti (Site 1; 11,709 inhabitants; 19.3% > 65 years; located in the middle of a rural area) and Bagno a Ripoli (Village of Antella, site 2, 4704 inhabitants; 20.3% > 65 years; located immediately adjacent to the urban area of Florence). To obtain two representative samples of the population, the same two stage sampling procedure was used in each of the two sites. For the baseline cohort, in August 1998, a random sample of 1270 persons aged 65 years or older was randomly selected from the population registry of the two sites. Another 29 subjects were randomly selected among those who were 90 years old or older, until at least 30 men and 30 women from this age group were included in the sample. Finally, men and women randomly sampled from the age strata 20-29, 30-39, 40-49, 50-59, and 60-64 years were sequentially invited to participate in the study, until at least 30 men and 30 women for each decade from 20 to 59, and 15 men and 15 women aged 60 to 64 had been enrolled. The InChianti Study cohorts were assessed at baseline in 1998-2000, 3 years later, in 2001-2003 and 6 years later, in 2004-2006. A nine-year follow-up is now underway and will be completed in early 2009. As at the three- and six-year follow-ups, the nine-year follow-ups will repeat most elements of the baseline evaluation. Participants will be seen on the anniversary of their baseline study assessment. As at the baseline there will be three contacts with participants, once in their homes and on two subsequent occasions in the clinic. Subjects who refuse the interview will be contacted several more times, one month apart, before being considered definitive refusals. Interviews are to be conducted at the participants= homes by experienced interviewers. In persons who score 18 or less on the Mini Mental State Examination the interview will be administered to a proxy. Prior to beginning the interview, the full study will be explained to participants and/or their proxies and informed consent for participation in the study obtained.

Inchianti正在两个地点进行：Chianti的Greve（站点1； 11,709名居民； 19.3％> 65年；位于乡村地区的中部）和Bagno A Ripoli（Antella，Antella，Site 2，4704居民，居民居民； 20.3％> 65年; 20.3％> 65> 65> 65> 65> 65> 65> 65> 65> 65> 65> 65> 65> 65> 65> 65> 20.3％> 65> 65> 65> 65> 65％；为了获得两个人口的代表性样本，在两个地点中的每个地点使用了相同的两个阶段抽样程序。 对于基线队列，1998年8月，从两个地点的人口登记处随机选择了1270名65岁或65岁以上的人的随机样本。 在90岁或以上的患者中，随机选择了另外29名受试者，直到样本中包括至少30名男性和30名女性。 最后，从20-29、30-39、40-49、50-59和60 - 64岁的年龄阶层随机取样的男人和女性被依次邀请参加这项研究，直到每十年至少30至59岁至59岁至59岁的男性和30名妇女，以及15名男性和15名男性和15个年龄在60至64岁之间的男性和15名女性。 Inchianti研究队列在1998 - 2000年的基线评估，3年后，2001 - 2003年和6年后的2004 - 2006年。 现在正在进行九年的随访，并将在2009年初完成。在为期三年和六年的随访中，九年的随访将重复基线评估的大多数要素。 参与者将在其基线研究评估周年纪念日中看到。 在基线时，将与参与者进行三个接触，一次在他们的家中，随后在诊所发生两次接触。 在被视为确定性拒绝之前，将再与拒绝面试的受试者相隔几次，相隔一个月。 经验丰富的访调员将在参与者=家庭进行访谈。在迷你精神状态检查中得分18或以下的人，访谈将被管理给代理人。 在开始访谈之前，将向参与者和/或其代理人解释完整的研究，并获得知情同意，以参与​​所获得的研究。