The Gulf Coast MBCCOP

墨西哥湾沿岸 MBCCOP

• 批准号: 7488890
• 负责人: THADDEUS A BEEKER
• 金额: $ 53.99万
• 依托单位: PROVIDENCE HOSPITAL (MOBILE, AL)
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-24 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7488890
• 关键词: Affect; African American; Area; Cancer Patient; Caring; Cities; Clinic; Clinical Research; Clinical Trials; Collaborations; Communities; Community Clinical Oncology Program; Complex; Country; Disabled Persons; Disasters; Environment; Grant; Healthcare; Hurricane; Institution; Location; Medical; Medical center; Minority; Neighborhoods; Oncologist; Oncology Service, Hospital; Patients; Population; Prevention; Protocols documentation; Purpose; Research; Research Ethics Committees; Research Personnel; Resources; Services; Site; Structure; Work; base; cancer therapy; gulf coast

DESCRIPTION (provided by applicant): The purpose of this application is to provide continued access to NCI supported Cancer Treatment, Prevention and Control trials for the residents of the mid-Gulf Coast region. The mid-Gulf Coast has been severely damaged over the past three years as a result of repeated natural catastrophes, first with partial destruction of Pensacola, FL by hurricane Ivan, then New Orleans, Biloxi/Gulfport by hurricane Katrina. Rebuilding is far from complete, and healthcare services have been adversely affected with still only basic medical care available in some of the affected areas. As a result, sustaining more complex subspecialty care at national levels remains a persistent challenge. Although Mobile was also declared a federally disaster zone after Katrina, it had recovered much quicker than the communities to the West. This permitted continuation of MBCCOP related activities with little downtime and also providing continuation of followups and protocol care for displaced cancer patients of that region. Even before the storms, the next closest structures capable of providing NCI supported cooperative group studies were located in Birmingham, AL to the North (260 miles), to the East in Gainesville, FL (390 miles), and New Orleans, LA with Tulane, LSD and the Ochsner clinic (150 miles). With LSU having completely lost their entire hospitals and oncology services Tulane did partially, and Ochsner's capacity also remains compromised. The Gulf Coast MBCCOP had accrued 103 new patients to protocols and was the fifth highest accruing CCOP for control and prevention trials in the country during the previous years, as well as having 617 active patients in followup. The Biloxi/Gulfport affiliates of the Gulf Coast MBCCOP remain closed since Katrina. For administrative and for reasons of competition, the Gulf Coast MBCCOP grantee Institution, Mobile Infirmary Medical Center terminated the working relationship with the entire group of oncologists who supported the grant as Investigators. This disabled the grant and forced the NCI to terminate it. The same group of oncologists is now applying to revive the grant under a new Institution. The environment is ideal for minority based clinical research with a 46 percent African American population in the city of Mobile. Moreover, a MBCCOP is a regionally desperately needed community resource. The primary practice location of the clinic is located in downtown Mobile, an area with even a much higher concentration of minorities in these neighborhoods. Cooperative group studies are already in place at the new site and a new IRB of record has been established. Since the termination, in the interim period, the applicant group continues to take care of all tasks and responsibilities related to the MBCCOP such as followups. The previous PI of the grant, Dr. Conrad had performed research to investigate causes for the reluctance of African Americans in participation in clinical trials. We propose to expand on this in collaboration with Dr. Conrad who will serve so- a consultant nn thic nrnnneal

描述（由申请人提供）：本申请的目的是为中部海岸地区的居民提供继续访问NCI支持的癌症治疗，预防和控制试验。由于反复发生的自然灾难，在过去三年中，中海沿岸的海岸受到了严重破坏，首先是飓风伊万（Ivan），然后是新奥尔良（New Orleans）的pensacola，pensacola，hurricane katrina飓风。重建远非完整，医疗保健服务受到不利影响，但在某些受影响地区仍然只能提供基本的医疗服务。结果，在国家一级维持更复杂的亚专科护理仍然是一个持续的挑战。尽管在卡特里娜飓风之后，莫比尔也被宣布为联邦政府灾区，但它的恢复比西方的社区快得多。这允许延续MBCCOP相关活动，而停机时间很少，并且还为该地区流离失所的癌症患者提供了随访和方案护理。甚至在暴风雨前，能够提供NCI支持的合作小组研究的下一个最接近的结构位于北部的伯明翰（260英里），位于佛罗里达州盖恩斯维尔（390英里）的东部（390英里），以及LA与Tulane，LSD，LSD，LSD和Ochsner Clinic（150英里）的洛杉矶。随着LSU完全失去了整个医院和肿瘤科服务，图兰（Tulane）部分做到了，而奥克斯纳（Ochsner）的能力也仍然受到损害。墨西哥湾沿岸MBCCOP已将103名新患者纳入方案，并且是该国在该国进行对照和预防试验的第五大CCOP，并且在随访中有617名活跃患者。自卡特里娜飓风以来，墨西哥湾沿岸MBCCOP的比洛克西/墨西哥湾分支机构一直关闭。出于行政和竞争原因，墨西哥湾沿岸MBCCOP授予者机构，移动医疗中心终止了与支持该赠款作为调查人员的整个肿瘤学家的工作关系。这可以禁用赠款并迫使NCI终止。现在，同一批肿瘤学家正在申请新机构下的赠款。该环境是基于少数民族的临床研究的理想选择，在移动城市，非裔美国人人口为46％。此外，MBCCOP是一种迫切需要的社区资源。该诊所的主要实践位置位于莫比尔市中心，在这些社区中，少数民族集中得多。合作小组研究已经在新站点进行，并且已经建立了新的记录IRB。自终止以来，在临时期间，申请人组继续照顾与MBCCOP相关的所有任务和责任，例如后续行动。赠款的先前PI康拉德博士曾进行了研究，以调查非洲裔美国人参与临床试验的原因。我们建议与Conrad博士合作扩展这一点，康拉德博士将为SO-so-nn thic nrnnneal服务