Renovations at Johns Hopkins University to Support Expanded Macaque Production

约翰·霍普金斯大学进行翻修以支持扩大猕猴生产

• 批准号: 7627411
• 负责人: ROBERT J. ADAMS
• 金额: $ 50万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-16 至 2012-01-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7627411
• 关键词: Animal Model; Breeding; Deterioration; Development; Emergency Situation; Engineering; Ensure; Farming environment; Funding; Grant; Growth; Laboratory Animals; Macaca; Macaca mulatta; Macaca nemestrina; Production; Request for Proposals; Research; Resources; Universities; Water; animal care; meetings; nonhuman primate; programs

DESCRIPTION (provided by applicant): This proposal requests $500,000 to partially fund the renovation and refurbishment of Building 12 at the Johns Hopkins Research Farm to accommodate the growth of a P40 grant supported SPF Pigtail macaque colony (Robert J. Adams, PI, P40 RR019995-01A2, Development of an SPF Macaca nemestrina Breeding Colony). The animal care and use program of Johns Hopkins University is large and highly diversified involving a broad spectrum of laboratory animal species. Non-human primate use has long been a prominent feature of the program, and a rhesus monkey breeding colony (Macaca mulatta) has been maintained on the Hopkins Research Farm campus for decades to ensure that an ample supply of SPF rhesus macaques was available for our research programs. Beginning in 2003, we embarked upon the development of an SPF breeding colony for pigtail macaques (Macaca nemestrina) using institutional resources to meet the growing needs for this animal model in JHU research programs and to alleviate the difficulties we had encountered in obtaining this species for outside colonies. Building 12 has not been used for over 10 years, and has undergone some deterioration, but after extensive review by outside Architects and Engineers, it has been determined that the building can be renovated and refurbished relatively easily. Building 12 is adjacent to Building 13 in which the colony now resides. The two buildings will share an emergency electrical generator and water well requested as part of this proposal.

描述（由申请人提供）：该提案要求$ 500,000在约翰·霍普金斯研究农场（Johns Hopkins Research Farm）的12号建筑物的翻新和翻新资金，以适应P40赠款支持的SPF Pigtail猕猴（Robert J. Adams，PI，PI，P40 RR0199995-01A2，SPFFORONE）spfFORONE cOLONY NEMESTINA的开发约翰·霍普金斯大学的动物护理和使用计划是大型且高度多样化的，涉及各种实验室动物物种。长期以来，非人类的灵长类动物一直是该计划的重要特征，并且数十年来，在霍普金斯研究农场校园内维持了恒河猴猴子繁殖殖民地（Macaca Mulatta），以确保我们的研究计划可以提供充足的SPF恒河猴。从2003年开始，我们利用机构资源开始开发用于辫子猕猴（Macaca nemestrina）的SPF育种菌落，以满足JHU研究计划中这种动物模型不断增长的需求，并减轻我们在获得该物种的外界菌落中遇到的困难。 12号建筑物已有10多年的历史，并且经历了一些恶化，但是经过外部建筑师和工程师的广泛审查，已经确定可以相对容易地翻新和翻新建筑物。 12号建筑物与殖民地现在居住的13号建筑物相邻。这两座建筑物将共享一个紧急电气发电机和水，作为该提案的一部分。