General Clinical Research Center

全科临床研究中心

• 批准号: 7616674
• 负责人: Carmen A Puliafito
• 金额: $ 829.23万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-23 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7616674
• 关键词: General; Clinical; Research; Center

DESCRIPTION (provided by applicant): This is a 3 year competing renewal application from the GCRC Program at the University of Southern California. The program has been funded for 46 years. It has had high levels of activity and scientific productivity in the current funding cycle. The Program has three components. The Parent GCRC (est. 1961) is located on the USC Health Sciences Campus. It serves investigators who conduct patient-oriented research in the large and multiethnic populations of central Los Angeles. Support for large-scale studies of disease mechanisms and treatment is an important feature of the parent GCRC. The bulk of the Parent GCRC will be moving to new and expanded facilities in USC University Hospital at the start of the next grant cycle. The Satellite GCRC at Childrens Hospital Los Angeles (est. 1995) is located in the largest pediatric hospital in the Western U.S. The CHLA Satellite serves pediatric investigators who conduct studies in the multiethnic pediatric population of central Los Angeles. The satellite was initially developed with a major theme of gene transfer research. The complexities that have evolved in that field led to underutilization of CHLA early in the current grant cycle. CHLA responded with strong institutional support, including (a) hiring of a new Director of Clinical Research, who also heads the GCRC satellite and (b) provision of new outpatient research space and administrative space. The CHLA satellite GCRC has rapidly re-vitalized and now supports a broad array of pediatric research. The Satellite GCRC at City of Hope National Medical Center (est. 1998) is located in a free-standing cancer and diabetes research institute in the San Gabriel Valley. This satellite serves investigators who are developing novel therapies for cancer and diabetes using cell-based and immunological approaches. This center has matured during the present grant cycle with significant increases in patient visits and new phase I or first-in-human trials. The USC GCRC program is a leader in clinical research, bringing together a broad spectrum of high-quality clinical investigation and outstanding human research infrastructure to serve a highly diverse patient population.

描述（由申请人提供）：这是南加州大学GCRC计划的3年竞争续约申请。该计划已资助了46年。它在当前的融资周期中具有高水平的活动和科学生产力。该程序有三个组件。 家长GCRC（Est。1961）位于USC Health Sciences校园。它为研究人员提供服务，这些研究人员在洛杉矶中部的大型和多种族人口中进行以患者为导向的研究。对疾病机制和治疗的大规模研究的支持是父GCRC的重要特征。下一个赠款周期开始时，大部分家长GCRC将搬到南加州大学大学医院的新设施。 洛杉矶儿童医院（Est。1995）的卫星GCRC位于美国西部最大的儿科医院，CHLA卫星为在洛杉矶中部多种族儿科进行研究的儿科研究人员服务。该卫星最初以基因转移研究的主要主题开发。在该领域进化的复杂性导致CHLA在当前赠款周期的早期缺乏利用。 CHLA在有力的机构支持方面做出了反应，包括（a）雇用新的临床研究主管，后者还负责GCRC卫星和（b）提供新的门诊研究空间和行政空间。 CHLA卫星GCRC已迅速重新活跃，现在支持了一系列的小儿研究。 希望市政府医疗中心（Est。1998）的卫星GCRC位于圣加布里埃尔河谷的独立癌症和糖尿病研究所中。该卫星为调查人员提供服务，这些研究人员正在使用基于细胞的和免疫学方法开发新的癌症和糖尿病疗法。该中心在目前的赠款周期中已经成熟，患者就诊和新阶段或人类第一阶段试验的显着增加。 USC GCRC计划是临床研究的领导者，汇集了广泛的高质量临床研究和出色的人类研究基础设施，以服务于高度多样化的患者人群。