Specimen Bank Core

样本库核心

• 批准号: 7938738
• 负责人: JOHN S GREENSPAN
• 金额: $ 23.94万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7938738
• 关键词: Acquired Immunodeficiency Syndrome; Aliquot; Asia; Cerebrospinal Fluid; Clinical; Clinical Research; Clinical Trials; Collaborations; Collection; Consultations; Deposition; Education; Equipment and supply inventories; Failure; Freezing; Funding; Goals; HIV; HIV Infections; Human immunodeficiency virus test; International; Investigation; Leukocytes; Oral; Population Sciences; Procedures; Process; Research; Research Infrastructure; Research Personnel; Saliva; San Francisco; Seminal fluid; Serum; Services; Shipping; Ships; Source; Specimen; Swab; Training; Translational Research; United States National Institutes of Health; Urine; Vagina; Vaginal Douching; Whole Blood; Woman; base; cohort; member; men; mindfulness-based stress reduction; repository; sample collection; tissue fixing

The UCSF-GIVI CFAR Specimen Bank Core has since 1987 provided expertise and an infrastructure for the collection, processing and storage of biospecimens for CFAR investigators. The Specimen Bank Core, under the director of Dr. John S. Greenspan and Ms. Yvonne De Souza has provided repository services to many cohorts and clinical studies based in San Francisco, including the Women's Interagency HIV Study (WINS), Options Project (Primary HIV infection), Staying Well (Clinical trial of mindfulness-based stress reduction and education groups for HIV), SFGH Observational Cohort Evaluating Long-Term Consequences of Virologic Failure (SCOPE), and a recently funded NIH study, Men of Asia testing for HIV (MATH). The Specimen Bank Core has received over 295,000 deposits and has shipped over 275,000 specimens aliquots worldwide, including whole blood, serum, plasma, leukocytes, fresh frozen and fixed tissue, urine, saliva (stimulated and unstimulated), semen, cerebrospinal fluid, oral and vaginal mucosal swabs, and cervico-vaginal lavage. A goal of the Core is to continue its current repository functions and to further develop as a local and national source for investigators pursing translational research. Specific Aims of the Specimen Bank Core (SBC) are to: 1. Process, inventory, and store (short and long term) biospecimens collected from CFAR investigators. 2. Provide well-characterized biospecimens to support CFAR investigations and to provide specimens to non-CFAR investigators to enhance collaboration between CFAR and non-CFAR investigators. 3. Provide consultation and training for CFAR investigators seeking information on optimal specimen collection, processing, storage, and shipment. 4. Advise the International Core in specimen banking and storage procedures.

自1987年以来，UCSF-GIVI CFAR标本库核心提供了专业知识和基础设施 CFAR研究人员的生物测量收集，加工和存储。标本库核心， 在约翰·S·格林斯潘（John S. Greenspan）博士和伊冯·德·索扎（Yvonne de Souza）女士的主任的领导下， 许多总部位于旧金山的队列和临床研究，包括妇女的机构艾滋病毒研究 （获胜），期权项目（原发性艾滋病毒感染），保持良好（基于正念的压力的临床试验 艾滋病毒的减少和教育小组），SFGH观察队列评估长期后果 病毒学衰竭（范围）和最近资助的NIH研究，亚洲男性对艾滋病毒的测试（数学）。 标本库核心已收到超过295,000个存款，并已发货超过275,000个标本 全球等分试样，包括全血，血清，血浆，白细胞，新鲜冷冻和固定组织，尿液， 唾液（刺激和未刺激），精液，脑脊液，口服和阴道粘膜拭子，以及 子宫颈灌洗。核心的目标是继续其当前的存储库功能并进一步 发展是研究转化研究的地方和国家来源。 标本库核心（SBC）的具体目的是： 1。从CFAR调查人员收集的过程，库存和存储（短期和长期）生物测量。 2。提供良好的生物测量以支持CFAR调查并为标本提供标本 非CFAR研究人员可以加强CFAR与非FFAR研究人员之间的合作。 3。为CFAR调查人员提供咨询和培训，以寻求有关最佳标本的信息 收集，加工，存储和装运。 4。在标本银行和存储程序中建议国际核心。