Interdisciplinary Predoctoral Training in Molecular Biophysics

分子生物物理学跨学科博士前培训

基本信息

批准号：
10646482
负责人：
JOSEPH J FALKE
金额：
$ 54.65万
依托单位：
UNIVERSITY OF COLORADO
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-07-01 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10646482
关键词：
Biophysics Molecular Training pre-doctoral

项目摘要

SUMMARY This new proposal seeks continuing support for a proven and thriving T32 Molecular Biophysics Predoctoral Training Program at the University of Colorado, Boulder (CU), currently in its 19th year. The goal of the Biophysics Training Program is to provide exceptional training to a diverse cohort of promising trainees, thereby preparing them for leading-edge research careers at the interface of Biology, Chemistry, Engineering and Physics – or for a broad range of other careers. The 39 training faculty include internationally recognized established investigators and rising young stars from 5 PhD-granting departments: Biochemistry, Chemical & Biological Engineering, Chemistry, Molecular, Cellular & Developmental Biology, and Physics. These faculty and their students use state-of-the-art biophysical approaches to elucidate fundamental aspects of macromolecular structure, dynamics, mechanism, and regulation in systems ranging from single molecules to live cells, with direct relevance to human health. Biophysics is one of the core areas of research on the Boulder campus. Of the 39 training faculty, 22 were hired since the program began, including 10 in the last 5 years. The Biophysics Training Program has been a key driving force behind this growth. The training program, jointly supported by NIH and CU Boulder funds, has established a thriving biophysical community with extensive collaborations and large numbers of joint between biophysicists in different laboratories and departments. Moreover, the program provides highly robust, innovative training for predoctoral students of biophysics, ensuring they receive a broad, interdisciplinary foundation needed for current and future success. The newly enhanced training program combines successful features of the existing program with new elements designed to further increase program diversity and prepare students to effectively navigate the constantly evolving modern workforce. Trainees focus on their home PhD program in year 1, then are appointed as Biophysics trainees in years 2-3 of their graduate studies. Required program elements include core Biophysics courses and training in Responsible Conduct of Research (RCR) and Rigor and Reproducibility (R&R). An array of other program activities, many newly added, provide training in critical thinking, self-efficacy, technical expertise, social proficiency, ethical grounding, sound scientific method, professional skills, teamwork, and leadership skills. The Biophysics trainees, faculty, courses and other program elements are regularly assessed to enable timely, effective responses to excellence and challenges as they arise. Strong outcomes indicate that the program provides highly effective training and support to Biophysics trainees, as demonstrated by 1) recruitment of high quality students and faculty, 2) increased participation by underrepresented groups, 3) strong trainee publication, graduation, and career placement rates, 4) extensive collaborations between training laboratories, and 5) training innovations.

概括这项新提案寻求对经过验证且蓬勃发展的 T32 分子生物物理学的持续支持科罗拉多大学博尔德分校 (CU) 的博士前培训项目目前已进入第 19 个年头。生物物理学培训计划的目标是为多样化的有前途的群体提供卓越的培训学员，从而为他们在生物学、化学、工程和物理 – 或广泛的其他职业包括 39 名培训教师。国际公认的知名研究人员和来自 5 名博士学位授予者的后起之秀部门：生物化学、化学与生物工程、化学、分子、细胞与发育生物学和物理学这些教师和学生使用最先进的生物物理学。阐明大分子结构、动力学、机制和作用的基本方面的方法从单分子到活细胞的系统调节，与人类健康直接相关。生物物理学是博尔德校区的核心研究领域之一，在 39 名培训教师中，有 22 名。自该计划开始以来，已聘用了 10 名员工，其中 10 名是在过去 5 年中聘用的。该培训计划由 NIH 和 CU 共同支持。博尔德基金建立了一个蓬勃发展的生物物理社区，广泛合作和大规模不同实验室和部门的生物物理学家之间的联合数量。为生物物理学博士前学生提供高度稳健、创新的培训，确保他们获得当前和未来的成功所需的广泛的跨学科基础。该计划将现有计划的成功特征与旨在进一步发展的新元素相结合增加课程多样性，让学生做好准备，有效应对不断发展的现代社会学员在第一年专注于他们的家庭博士课程，然后被任命为生物物理学。研究生学习第 2-3 年的学员所需的课程内容包括核心生物物理学。负责任的研究行为 (RCR) 以及严谨性和可重复性 (R&R) 的课程和培训。一系列其他计划活动（许多是新增加的）提供批判性思维、自我效能、技术专长、社交能力、道德基础、健全的科学方法、专业技能、生物物理学学员、教师、课程和其他项目要素。定期评估，以便及时、有效地应对出现的卓越和挑战。强劲的成果表明该计划为以下人员提供了高效的培训和支持：生物物理学实习生，表现为 1) 招募高素质学生和教师，2) 增加代表性不足群体的参与，3) 强大的实习生出版物、毕业和职业生涯安置率，4) 培训实验室之间的广泛合作，以及 5) 培训创新。