Parkinson Disease Neuroprotection Clinical Trial

帕金森病神经保护临床试验

• 批准号: 7558540
• 负责人: DANIEL D TRUONG
• 金额: $ 3.06万
• 依托单位: LONG BEACH MEMORIAL MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-15 至 2011-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7558540
• 关键词: Administrator; Affect; Boxing; Brain; Businesses; Caregivers; Cell Nucleus; Cells; Clinical; Clinical Trials; Collaborations; Diabetic Neuropathies; Diagnosis; Doctor of Medicine; Drug Storage; Dystonia; Electrocardiogram; Enrollment; Equipment; Functional disorder; Goals; Health; Hospitals; Human Resources; Institutes; Light; Location; Marketing; Medical center; Multiple Sclerosis; Myoclonus; Neurologic; Neuroprotective Agents; Oranges; Parking Facilities; Parkinson Disease; Patient Recruitments; Patients; Phase; Phase III Clinical Trials; Pigments; Protocols documentation; Research; Research Design; Research Institute; Research Personnel; Restless Legs Syndrome; Site; Staging; Substantia nigra structure; Symptoms; Television; Testing; Tremor; Venous blood sampling; X-Ray Film; expectation; health related quality of life; improved; meetings; neuron loss; neuroprotection; prevent

DESCRIPTION (provided by applicant): This is an application to join a multi-center trial collaboration to test potential neuroprotective agents in Parkinson's disease. The specific protocol and study design will be developed by the steering committee by which all sites will abide. We are a Research Institute consisting of a President and Clinical Director, 5 Investigators, 4 Research Coordinators and 1 Business Administrator who handles marketing, patient recruitment and human resources. We have conducted over 20 clinical trials (Phases IB, II, III and IV) involving various stages of Parkinson's disease and other neurological conditions, including Restless Leg Syndrome, dystonia, tremor, myoclonus, multiple sclerosis, and diabetic neuropathy. In the trials involving Parkinson's disease, we have met and/or exceed enrollment expectations. In six of these, we were the highest enroller and/or in the top 20% of all sites regarding enrollment. At our institute location adjacent to the Orange Coast Memorial Medical Center, we have six patient exam rooms, one large research room dedicated to clinical trials, one room for phlebotomy/drug storage/equipment, countertop centrifuge, refrigerated centrifuge, ECG machine, sphingmometers, light box for viewing films/X-rays, EMG machine, one subzero freezer (-40 degrees), 2 refrigerator/freezers, a waiting room, video, and television. There is a mutli-level parking facility next to the hospital with cafeteria.

描述（由申请人提供）：这是一项加入多中心试验合作的申请，以测试帕金森氏病中潜在的神经保护剂。具体的协议和研究设计将由指导委员会开发，所有站点都将遵守。我们是一家研究所，由总裁兼临床主任，5位研究人员，4位研究协调员和1名业务管理员组成，负责处理营销，招聘和人力资源。我们已经进行了20多次临床试验（阶段IB，II，III和IV），涉及帕金森氏病和其他神经系统疾病的各个阶段，包括躁动不安的腿综合征，肌张力障碍，颤音，肌酸，多发性硬化症和糖尿病神经病。在涉及帕金森氏病的试验中，我们已经达到和/或超过了入学期望。在其中的六个中，我们是最高的入学者和/或在所有站点的前20％，涉及入学人数。在我们的研究所，在橙色海岸纪念医疗中心附近，我们有六个患者检查室，一个专门用于临床试验的大型研究室，一个用于临床试验的大型研究室，用于静脉切开术/药物存储/设备的一个室，台面离心机，冷藏离心机，ECG机器，ECG机器，SphinghingMometers，sphingmometers，用于查看膜/X轮的轻盒，X-Rays，Emg Machine，Emg Machine（Emg Machine），emg Machine（Emg Machine）（emg Machine）（emg Machine）（ - 40 sub）（40 subse）（40 subser）（40）。冰箱/冰柜，候诊室，视频和电视。自助餐厅的医院旁边有一个Mutli级停车设施。