Young Adult Follow-Up of Girls with ADHD

患有多动症的女孩的年轻成人随访

• 批准号: 7665340
• 负责人: STEPHEN HINSHAW
• 金额: $ 23.06万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-04-01 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7665340
• 关键词: Accidental Injury; Adolescence; Adolescent; Adult; Advertisements; Age; Aggressive behavior; Anxiety; Area; Attention deficit hyperactivity disorder; Attenuated; Behavior; Bulimia; Camping; Caucasians; Caucasoid Race; Characteristics; Childhood; Clinic; Clinical; Cognitive; Cognitive deficits; Comorbidity; Data; Data Collection; Data Set; Development; Diagnosis; Diagnostic; Eating; Eating Disorders; Epidemiologic Methods; Ethnic Origin; Etiology; Evaluation; Failure; Family; Family Process; Family Relationship; Female; Friendships; Functional disorder; Funding; Impairment; Impulsive Behavior; Individual; Intelligence; Investigation; Knowledge; Language; Measures; Mediating; Methods; Modeling; Motor; Nature; Neuropsychological Tests; Outcome; Participant; Pathology; Pattern; Performance; Personality Traits; Pharmaceutical Preparations; Process; Progress Reports; Publishing; Race; Research; Research Design; Research Personnel; Risk; Sampling; San Francisco; Schools; Sex Characteristics; Social Functioning; Staging; Substance abuse problem; Symptoms; Time; Variant; Work; anti social; base; boys; depression; depressive symptoms; disturbance in affect; eating pathology; emerging adult; executive function; follow-up; girls; heuristics; informant; male; meetings; neuroimaging; neuropsychological; non-compliance; peer; person centered; programs; prospective; psychopathic personality; racial and ethnic; resilience; service utilization; skills; social; social skills; socioeconomics; trait; treatment strategy; trend; young adult

DESCRIPTION (provided by applicant): Although attention-deficit/hyperactivity disorder (ADHD) is an impairing condition in girls, research focused on the long-term, prospective follow-up of girls with ADHD is extremely rare. The chief objective of this proposal is to perform a rigorous, prospective, 10-year follow-up investigation of a well-characterized, ethnically and socioeconomically diverse sample of girls with ADHD (n = 140), plus an age- and ethnicity/ race-matched sample of comparison girls (n = 88), who were initially ascertained and studied in naturalistic research summer programs between the ages of 6 and 12 years (Wave 1) and who received an extensive 5-year follow-up in early to mid-adolescence (Wave 2), which featured a retention rate of 92% of the sample. Key aims for the Wave 3 assessments, during late adolescence/young adulthood, are to (a) characterize outcomes of these individuals across multiple domains of functioning: ADHD symptoms, externalizing and internalizing symptoms (including antisocial behavior, mood disturbance, and eating pathology), substance use/abuse, academic performance, neuropsychological skills, peer and family relations, accidental injury, and service utilization; (b) describe and understand trajectories of development from childhood through early adulthood; (c) relate academic and social functioning to the continued presence of executive functioning deficits; and (d) explain patterns of pathology and resilience during this crucial developmental period that encompasses the expected transition to independent functioning. It is predicted that girls with ADHD will be at risk for a wider range of pathology and impairments than boys with ADHD, necessitating the assessment of a diverse array of outcome variables. The proposed investigation features psychometrically rigorous, multi-method, and multi-informant evaluations, utilizing staff who will be unaware of the initial diagnostic status of the participants. Given the increasing evidence for the difficult long-term outcomes of males with ADHD, understanding female outcomes and developmental trajectories is a clinical and scientific priority.

描述（由申请人提供）：尽管注意力缺陷/多动症（ADHD）是女孩的疾病，但研究的研究重点是多动症女孩的长期，前瞻性随访。该提议的主要目的是对ADHD的女孩的特征良好，种族和社会经济上的良好特征，种族和社会经济多样化的样本进行严格，前瞻性，10年的随访调查（n = 140）（n = 140），再加上年龄和种族/种族/种族比较样本的比较女孩（n = 88）（n = 88）（n = 88），他们最初确定了夏季和研究的人，他们是最初确定和研究的人，他们是6年级的，他们是6年级的浪潮（又是6年浪潮（浪潮）（浪潮）（浪潮）（潮流中的1.1年）（浪潮）（又是6年的浪潮）（浪潮）（又有1年的浪潮（青春期早期至中期的随访（第2波），其保留率为92％的样本。在青春期/成年期间，对第三波评估的关键目的是（a）表征这些人在多个功能领域中的结果：ADHD症状，外部化和内在化症状（包括反社会行为，情绪障碍和饮食病理学），药物滥用/虐待/滥用/学术绩效，学术绩效，学术性，神经心理学技能和家庭关系，偶然的损害，偶然的uti; （b）描述和理解从童年到成年初期发展的发展轨迹； （c）将学术和社会功能与执行功能不足的持续存在相关联； （d）解释在这个关键的发展时期的病理和韧性模式，该模式涵盖了预期过渡到独立功能的过渡。据预测，患有多动症的女孩将面临更广泛的病理和障碍的风险，而不是多动症的男孩，需要评估各种结果变量。拟议的调查具有精神法法上的严格，多方法和多信息评估，利用将不了解参与者最初诊断状态的员工。鉴于越来越多的ADHD男性长期结局的证据，了解女性的结果和发育轨迹是临床和科学的优先事项。