CORE--BIOSTATISTICS AND INFORMATION SYSTEMS

核心——生物统计与信息系统

• 批准号: 7682562
• 负责人: STEPHEN L GEORGE
• 金额: $ 33.42万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7682562
• 关键词: Area; Bioinformatics; Biometry; Biostatistics Core; Brain Neoplasms; Cancer Center; Cancer and Leukemia Group B; Clinical; Clinical Research; Clinical Trials; Collaborations; Collection; Computer software; Data; Data Collection; Databases; Development; Doctor of Philosophy; Electronics; Ensure; Genetic; Health Insurance Portability and Accountability Act; Human Resources; Individual; Informatics; Information Systems; Investigation; Laboratory Study; Leadership; Malignant neoplasm of brain; Memory; Pathology; Process; Quality Control; Reproduction spores; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Specimen; Structure; Time; Tissue Banks; base; biomedical scientist; cancer research center director; data management; design; falls; pre-clinical; research and development; success

The Biostatistics and Informatics Core for the Duke SPORE in Brain Cancer supports the statistical, bioinformatics and information systems needs of all projects and cores in the SPORE. The Core was developed as a collaboration between Cancer Center Biostatistics and Cancer Center Information Systems (CCIS). Dr. Stephen L. George, Ph.D., Director of Cancer Center Biostatistics and Group Statistician for the CALGB and Kimberly Johnson, Director of Cancer Center Information Systems are Co-Directors of the Core. Dr. George will direct biostatistics and bioinformatics initiatives in this area, while Ms. Johnson will direct information systems initiatives and assist Dr. George in administering the Core. CCIS falls under the administrative oversight of Dr. George within the Cancer Center. Additional staff for this Core includes statisticians and programmers dedicated to each project and core based on their area of expertise and past associations with individual projects. In addition to the core directors, partial support is requested for three statistical personnel (.70 FTE total), one bioinformatician (.10 FTE), two information systems personnel (.55 FTE total) and one full-time data manager. This Core will provide assistance in the statistical analysis of clinical, pre-clinical and laboratory studies, as well as genetic investigations. In addition, the Core will support the development of research database structures and data management activities. The Core will use existing computing infrastructure resources as an efficient means to support SPORE research and will build on past successes in infrastructure development. Resources available to this Core include 25 servers supported by CCIS, offering over 20GB of memory and 2 TB of disk space with multi-processing capabilities and a variety of software applications and compilers.

脑癌杜克孢子的生物统计学和信息学核心支持孢子中所有项目和核心的统计，生物信息学和信息系统需求。核心是作为癌症中心生物统计学与癌症中心信息系统（CCIS）之间的合作开发的。癌症中心生物统计学和小组统计学家的Stephen L. George博士和Calgb的小组统计学家和Kimberly Johnson，癌症中心信息系统总监是核心的联合主任。 乔治博士将在该领域指导生物统计学和生物信息学计划，而约翰逊女士将指导信息系统计划，并协助乔治博士管理核心。 CCI属于癌症中心乔治博士的行政监督。 该核心的其他员工包括统计学家和程序员根据每个项目和核心的专业知识领域以及与个别项目的过去关联。除核心董事外，还要求对三名统计人员（总计.70 FTE），一名生物信息学家（.10 FTE），两个信息系统人员（.55 FTE总计）和一名全日制数据经理提供部分支持。 该核心将在临床，临床前和实验室研究以及遗传研究的统计分析中提供帮助。此外，核心将支持研究数据库结构和数据管理活动的开发。核心将使用现有的计算基础设施资源作为支持孢子研究的有效手段，并将基于基础架构开发的过去成功。该核心可用的资源包括CCIS支持的25台服务器，提供20GB的内存和2 TB的磁盘空间，具有多处理功能以及各种软件应用程序和编译器。