Administration Core

行政核心

基本信息

批准号：
7465918
负责人：
WILLIAM M. SUGDEN
金额：
$ 4.36万
依托单位：
UNIVERSITY OF WISCONSIN-MADISON
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-05-01 至 2013-04-30
项目状态：
已结题

项目摘要

Role of the Administrative Core The Administrative Core provides both administrative as well as intellectual oversight and guidance and financial accounting for the Program. Ms. Bette Sheehan and Mr. Randy Martinson provide the administrative and financial expertise required for this Core. Ms. Bette Sheehan oversees the communal administrative services for this program. She organizes the weekly student and postdoctoral seminars initiated and maintained by this Program. She administers and facilitates each project's fulfilling the ever-increasing documentation required to carry out our research including human subjects safety approval, vertebrate animal use approval, biological safety approval, and chemical safety approval. She organizes meetings of the project leaders, archiving their manuscripts, and overseeing their students' committee meetings. It is these efforts that provide one means for Dr. Sugden as the principal investigator to stay abreast of the current research carried out by Program members. His weekly meetings with the Project leaders and their combined weekly staff meeting, which is also organized by Ms. Sheehan, provides a second means for Dr. Sugden to affect this Program's research. Ms. Sheehan will also organize the visits of our scientific advisory board members. We propose to bring the members individually and sometimes together to Madison to foster excellence in our cancer research. Mr. Randy Martinson oversees the financial accounting for this Program-Project grant. He provides each project leader ongoing reports of their budgets and expenditures and informs Dr. Sugden of potential difficulties before they occur. He is instrumental in obtaining the most competitive prices for the supplies we use. For example, he organized the Program's initiating a contract with a vendor of restriction endonucleases which provides us not only the lowest possible prices but also immediate access to them, their being stored in McArdle. Mr. Martinson also guides project leaders in their projecting accurately future budgets and in meeting the accounting demands of federal and state governments, the University, and the Medical School through which the Program's funds are administered. Intellectual oversight and guidance is provided by two facets of this core. Dr. Sugden usually meets with project leaders multiple times per week to discuss science and personnel. He is a member on the dissertation committees of the majority of the graduate students carrying out the research of this program. He reads many of the manuscripts describing this program's research in their initial draft form and suggests revisions where appropriate. It is also clear that all of the project leaders are established experts in their fields so that a major contribution Dr. Sugden has and will continue to make to this program is to foster collaboration between them. For example, it is in part through his efforts that Drs. Paul Ahlquist and Paul Lambert and he have united in their goal to identify additional human cancers that may be caused by human tumor viruses. The second facet by which this core will provide intellectual oversight and guidance for its research is through its scientific advisory board. Four experts whose research overlaps project areas shall come and review the program's science critically each year. Dr. DiMaio is an expert in papillomaviruses with a breadth of understanding of virology in general. Dr. Rooney is an expert in Epstein-Barr virus with experience in developing research findings into effective therapies for treating EBV-associated cancers. They are not being asked to critique the grant application but rather to visit and critically review ongoing research. The project leaders and key researchers will present their current and proposed research for all to discuss. The program members want these expert colleagues to grow to know their science and .to help their collaborations flourish. Dr. Sugden will meet privately with the advisors at the end of each visit to seek any sensitive suggestions about his fostering the success of the program.

行政核心的作用行政核心提供行政以及智力监督和指导以及该计划的财务会计。 Bette Sheehan 女士和 Randy Martinson 先生提供行政服务以及该核心所需的财务专业知识。 Bette Sheehan 女士负责监督该计划的社区行政服务。她组织由该计划发起和维持的每周学生和博士后研讨会。她管理并促进每个项目完成我们研究所需的不断增加的文档包括人类受试者安全批准、脊椎动物使用批准、生物安全批准，以及化学品安全审批。她组织项目负责人的会议，归档他们的手稿，并监督学生委员会会议。正是这些努力为萨格登博士提供了一种手段主要研究者及时了解计划成员当前进行的研究。他的与项目负责人举行的每周会议以及每周联合举行的员工会议由 Sheehan 女士撰写，为 Sugden 博士提供了影响该计划研究的第二种方法。希恩女士还将组织我们的科学顾问委员会成员的访问。我们建议带成员单独或有时共同前往麦迪逊，以促进我们癌症研究的卓越发展。兰迪·马丁森 (Randy Martinson) 先生负责监督该计划-项目补助金的财务会计。他提供每个项目负责人持续报告其预算和支出，并告知 Sugden 博士潜在的潜力在困难发生之前。他在我们的供应品获得最具竞争力的价格方面发挥了重要作用使用。例如，他组织了该计划与限制性内切酶供应商签订合同这不仅为我们提供了尽可能最低的价格，而且还可以立即获得它们，它们是保存在麦卡德尔。马丁森先生还指导项目负责人准确预测未来预算并满足联邦和州政府、大学和医学界的会计要求管理该计划资金的学校。该核心的两个方面提供智力监督和指导。萨格登博士通常会见每周多次与项目负责人讨论科学和人员问题。他是该组织的成员由大多数研究生组成的论文委员会进行该项目的研究。他阅读了许多描述该项目研究的初稿手稿，并提出建议酌情进行修订。同样明显的是，所有项目负责人都是各自领域的知名专家。因此，Sugden 博士已经并将继续为该计划做出的主要贡献是促进他们之间的合作。例如，部分通过他的努力，博士。保罗·阿尔奎斯特和保罗兰伯特和他一致致力于确定可能由以下原因引起的其他人类癌症：人类肿瘤病毒。第二个方面，该核心将为其研究提供智力监督和指导是通过其科学顾问委员会进行的。应有四名研究与项目领域重叠的专家前来每年都会批判性地审查该计划的科学性。 DiMaio 博士是乳头瘤病毒方面的专家，具有广泛的研究领域对病毒学的一般理解。鲁尼博士是 Epstein-Barr 病毒方面的专家，在以下领域拥有丰富的经验：将研究成果开发为治疗 EB 病毒相关癌症的有效疗法。他们不是被要求批评资助申请，而是访问并严格审查正在进行的研究。这项目负责人和主要研究人员将介绍他们当前和拟议的研究供所有人讨论。这计划成员希望这些专家同事能够不断了解他们的科学并帮助他们合作蓬勃发展。 Sugden 博士将在每次访问结束时与顾问私下会面，寻求任何建议关于他促进该计划成功的敏感建议。