Adolescent Medicine Trials Network for HIV/AIDS Interve*

艾滋病毒/艾滋病干预青少年医学试验网络*

• 批准号: 7580937
• 负责人: Steven Daniel Douglas
• 金额: $ 72.53万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-16 至 2011-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7580937
• 关键词: 12 year old; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adolescent Medicine; Adolescent Medicine Trials Network; Behavioral; Behavioral Research; Caring; Clinical; Clinical Research; Clinical Services; Clinical Trials; Clinical Trials Unit; Collaborations; Communities; Complex; Comprehensive Health Care; Data; Data Analyses; Development; Disease; Environment; Epidemic; Functional disorder; Goals; HIV; HIV Infections; Health; Individual; Infection; Intervention; Learning; Life; Link; Manuscripts; Medical Research; Methods; Modeling; Pediatric Hospitals; Pennsylvania; Persons; Pharmaceutical Preparations; Philadelphia; Population; Preparation; Primary Prevention; Protocols documentation; Public Health; Qualifying; Recruitment Activity; Research; Research Activity; Research Support; Risk; Safety; Secondary Prevention; Services; Site; Testing; Therapeutic; United States Health Resources and Services Administration; Universities; Work; Youth; design; improved; innovation; medical schools; meetings; multidisciplinary; outreach; pediatric AIDS; performance site; prevent; programs; protocol development; research facility; social; symposium; tertiary prevention; young adult

Project Summary and Relevance: The Adolescent Trials Unit at The Children's Hospital of Philadelphia seeks to continue their work with the Adolescent Trials Network for HIV/AIDS Interventions. The site will conduct clinical studies developed or co-endorsed by the ATM that will focus on the following: 1) primary prevention through the Connect to Protect project. 2) secondary prevention through ATM clinical studies including both behavioral and biomedical interventions. 3) tertiary prevention through ATN clinical studies including therapeutic and behavioral trials targeting infected, ill youth. The site will accomplish these goals as follows. The Connect to Protect Project will continue to build community mobilization and partnerships through participation in ATN 016B, ATN 040,and other C2P specific studies. To address the second and third aims, the site will recruit and retain HIV-infected and at-risk youth into clinical trials. To accomplish this goal successfully, the site will continue with their targeted outreach and linkage program to identifyHIV- infected youth and link them to care. The site will provide a broad array of targeted, multidisciplinary services to support youth once engaged in research. The site PI will continue to work with the TLG to develop and implement the therapeutic agenda of the Network. Other staff will support the research agenda through participation on protocol teams. Finally, the site will contribute to the Network management through active participation in conference calls and meetings. This project addresses the epidemic of HIV infection in adolescents and young adults to provide the much needed scientific data to prevent new infections and maintain the health of those infected. The data from the clinical trials developed and implemented by the ATN will contribute significantly to understanding better ways to treat HIV infection in adolescents and prevent new infections from occurring. Relevance: This project will have major public health implications. Through well designed targeted clinical trials, the much needed data will be collected to learn better how to prevent the spread of new HIV infections in adolescents and young adults. The trials with HIV-infected adolescents and young adults will provide data required to prevent the spread of HIV from infected persons through better management strategies for infected individuals. .

项目摘要和相关性：费城儿童医院的青少年试验部门 寻求通过青少年试验网络继续进行艾滋病毒/艾滋病干预措施的工作。该网站将 进行由ATM开发或共同说明的临床研究，该研究将重点介绍以下：1）主要 通过连接进行预防以保护项目。 2）通过ATM临床研究预防二级预防 包括行为和生物医学干预措施。 3）通过ATN临床研究预防三级预防 包括针对感染，病青年的治疗和行为试验。该网站将实现这些目标 如下。与保护项目的连接将继续建立社区动员和伙伴关系 通过参与ATN 016B，ATN 040和其他C2P特定研究。解决第二个 第三目的是，该网站将招募并保留受HIV感染的和处于危险的青年参加临床试验。实现这一目标 成功的目标是，该网站将继续进行针对性的外展和链接计划，以识别HHIV- 感染青年并将他们与护理联系起来。该网站将提供一系列有针对性的多学科 一旦从事研究，支持青年的服务。该网站PI将继续与TLG合作 开发和实施网络的治疗议程。其他员工将支持研究议程 通过参与协议团队。最后，该网站将通过 积极参加电话会议和会议。该项目解决了艾滋病毒感染的流行 青少年和年轻人提供急需的科学数据，以防止新的感染和 保持受感染者的健康。来自临床试验的数据由 ATN将为了解青少年的艾滋病毒感染的更好方法做出重大贡献 防止新的感染发生。 相关性：该项目将具有重大的公共卫生影响。通过设计良好的目标临床 试验，将收集急需的数据，以了解如何防止新的HIV感染传播 在青少年和年轻人中。与HIV感染的青少年和年轻人的试验将提供数据 通过更好的管理策略来防止艾滋病毒传播的艾滋病毒传播 受感染的人。 。