BIOMARKERS IN HEALTH AND DISEASE

健康和疾病中的生物标志物

• 批准号: 7604788
• 负责人: Nancy J Cox
• 金额: $ 0.08万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7604788
• 关键词: Aliquot; Ambulatory Care Facilities; Biological; Biological Markers; Blood; Blood specimen; Clinical; Computer Retrieval of Information on Scientific Projects Database; DNA; Disease; Faculty; Funding; Future; Goals; Grant; Health; Institution; Investigation; Medical Records; Medicine; Patients; Plasma; Protocols documentation; Research; Research Infrastructure; Research Personnel; Research Proposals; Resources; Sampling; Source; Specimen; Time; Translational Research; United States National Institutes of Health; design; sample collection

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Biomarkers in Health and Disease is a protocol designed to build research infrastructure in the Dept. of Medicine. The protocol is the major activity of TRIDOM, the Translational Research Initiative in the Dept. of Medicine. Patients at Dept. of Medicine outpatient clinics are invited to participate in this study which requires them to answer a few short questions, give extra blood (20 ml) at the time of their next clinical blood draw, and be willing to allow us to access their medical record. The blood samples collected for the project are sent directly to the GCRC which extracts DNA, and aliquots DNA, plasma and serum for storage to use in future research investigations. The resulting sample collection is designed to facilitate research by Dept. of Medicine faculty and fellows by reducing the time and effort required to obtain biological specimens on sufficiently large samples to generate preliminary studies for research proposals. While this project is not focused on a single scientific question or specific research direction, large-scale sample collection efforts with goals similar to the goals of this project are now common at research institutions.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 健康与疾病的生物标志物是一项旨在在医学系建立研究基础设施的方案。 该方案是Tridom的主要活动，Tridom是医学系的转化研究计划。 邀请医学院门诊诊所的患者参加这项研究，要求他们回答一些简短的问题，在下一次临床抽血时给予额外的血液（20毫升），并愿意让我们获得病历。 为该项目收集的血液样本直接发送到提取DNA的GCRC，并将等分的DNA，等离子体和血清用于储存，以在未来的研究研究中使用。 由此产生的样本收集旨在通过减少在足够大样本上获得生物标本所需的时间和精力来促进医学系和研究员的研究，以生成初步研究研究建议。 尽管该项目不集中在一个科学问题或特定的研究方向上，但与该项目相似的目标的大规模样本收集工作现在在研究机构中很普遍。